Abstract Rheumatic heart disease (RHD) remains a neglected disease of poverty. While nearly eradicated in high‐income countries due to timely detection and treatment of acute rheumatic fever, RHD remains highly..
Read MoreAbstract Background The coronavirus disease 2019 (COVID‐19) pandemic poses broad challenges to healthcare systems and providers. The manifestations of this disease are still being described in a variety of different..
Read MoreAbstract If we think about plug‐in hybrids, the treatment of paravalvular leaks in cardiac surgery may not be the first thing that comes to mind. Yet, there appears to be..
Read MoreAbstract Background To investigate the impact of severe patient‐prosthesis mismatch (PPM) related to the Edwards Lifesciences Perimount (EP) bioprosthesis in the aortic position on early in‐hospital outcomes and long‐term survival...
Read MoreAbstract Objectives To explore the safety and efficacy of total thoracoscopic repair of ventricular septal defects (VSD). We compared clinical outcomes of VSD via a total thoracoscopic approach with those..
Read MoreAbstract Background We sought to clarify the benefit of cytokine adsorption in patients with COVID-19 supported with venovenous extracorporeal membrane oxygenation (ECMO). Methods We did a single-centre, open-label, randomised, controlled..
Read MoreAbstract Heart failure (HF) is a leading cause of morbidity and mortality in pregnant women in the United States. Although peripartum cardiomyopathy is the most common diagnosis for pregnant women..
Read MoreAbstract In this document, we propose a universal definition of heart failure (HF) as a clinical syndrome with symptoms and/or signs caused by a structural and/or functional cardiac abnormality and..
Read MoreAbstract In the early years of 2000, a growing enthusiasm toward robotic and minimally invasive techniques became more prevalent in the field of cardiac surgery. Robotically assisted surgical systems were..
Read MoreAbstract Objective Isolated tricuspid surgery through median sternotomy can be associated with a high morbidity and mortality. Reports of minimally invasive isolated tricuspid valve operations are rare, but the outcomes..
Read MoreAbstract Efforts to reduce the trauma and discomfort associated with thoracic and cardiac procedures in children have a long and complex history. While much of the early focus has been..
Read MoreAbstract Extracorporeal life support and extracorporeal membrane oxygenation (ECMO) are widely used for acute severe refractory cardiac and respiratory failure. An increasing number of patients are treated with ECMO worldwide. This can be attributed to..
Read MoreAbstract The transfusion of platelets for both prophylaxis and treatment of bleeding is relevant to all areas of medicine and surgery. Historically, guidance regarding platelet transfusion has been limited by..
Read MoreAbstract WHAT IS the purpose of trial registration and why is it so important to the integrity of research? Clinical trial registration serves the following purposes. First, by preregistering the..
Read MoreAbstract Extracorporeal circuits including renal replacement therapy, extracorporeal membrane oxygenation, and ventricular assist devices are increasingly used in critically ill patients. The need for anticoagulation to provide circuit patency and..
Read MoreAbstract Development of minimally invasive cardiac surgery (MICS) served the purpose of performing surgery while avoiding the surgical stress triggered by a full median sternotomy. Minimizing surgical trauma is associated..
Read MoreAbstract Background The ongoing coronavirus disease 2019 (Covid-19) pandemic presents challenges for surgeons of all disciplines, including cardiologists. The volume of cardiac surgery cases has to comply with the mandatory..
Read MoreAbstract Background Postoperative respiratory failure, defined as ventilator dependency for more than 48 hours or unplanned reintubation within 30 days, is a costly complication of cardiac surgery that increases mortality..
Read MoreAbstract Extracorporeal membrane oxygenation (ECMO) represents an established technique to provide temporary cardiac and/or pulmonary support. ECMO, in veno-venous, veno-arterial or in extracorporeal carbon dioxide removal modality, is associated with..
Read MoreAbstract The aim of this article is to provide a comprehensive review of the current state of knowledge on heparin-induced thrombocytopenia (HIT) in cardiac surgery. The management of HIT patients..
Read MoreAbstract Advanced epithelial ovarian cancer (EOC) has a well-characterized pattern of spread; the cancer cells tend to stay within the peritoneal cavity, attaching to organ surfaces and only invading superficial..
Read MoreAbstract Premature birth, defined as a gestational period less than 37 weeks, occurs in 8% of infants born in Canada. These births are associated with a higher risk of developing..
Read MoreAbstract Importance Tranexamic acid (TXA) is an efficient antifibrinolytic agent; however, concerns remain about the potential adverse effects, particularly vascular occlusive events, that may be associated with its use. Objective ..
Read MoreAbstract Background Extracorporeal membrane oxygenation (ECMO) is a potential treatment option in critically ill COVID-19 patients suffering from acute respiratory distress syndrome (ARDS) if mechanical ventilation (MV) is insufficient;..
Read MoreAbstract Objectives To evaluate the association of intraoperative urinary biomarker excretion during cardiac surgery and the subsequent development of acute kidney injury (AKI). Design Prospective, nonrandomized, observational study. Setting Single..
Read MoreAbstract Objectives The reduction of postoperative acute kidney injury in patients undergoing cardiopulmonary bypass surgery using an oxygen delivery-guided perfusion strategy (oxygen delivery strategy) for cardiopulmonary bypass management compared with..
Read MoreAbstract Objectives To examine the sensitivity and specificity of perioperative lactate gradients for the prediction of subsequent development in patients undergoing cardiovascular surgery. Design Retrospective, single-center, case-control study. Setting University hospital...
Read MoreAbstract Introduction Peritoneal carcinomatosis remains a condition with poor prognosis and limited therapeutic options. Pressurized Intrapertioneal Aerosol Chemotherapy (PIPAC) has been developed as a new tool for delivering intraperitoneal chemotherapy..
Read MoreAbstract Bleeding and thrombosis-related complications are common in pediatric cardiac patients supported by extracorporeal membrane oxygenation (ECMO) and are associated with morbidity and mortality. The purpose of this study was..
Read MoreAbstract Historically, the surgical literature was defined based on a predominance of case series, case reports, and anecdotal experiences of surgical investigators. But over the past several decades, the methodologic..
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