Abstract Background and Objective Simulation in may help clinicians understand the important events occurring during and . During the COVID-19 pandemic, a significant number of patients have required hospital admission to tertiary referral..
Read MoreAbstract Antiphospholipid syndrome (APS) is an acquired autoimmune condition characterized by the presence of antiphospholipid antibodies (lupus anticoagulant, anticardiolipin antibody, and anti-β2 glycoprotein-I antibody) which leads to clinical thrombosis via a..
Read MoreAbstract Introduction: Extracorporeal membrane oxygenation circuit performance can be compromised by oxygenator thrombosis. Stagnant blood flow in the oxygenator can increase the risk of thrombus formation. To minimize thrombogenic potential,..
Read MoreAbstract We describe the successful transplantation of a brain-dead donor supported by veno-arterial extracorporeal membrane oxygenation (VA-ECMO) after cardiac arrest secondary to pulmonary embolism. The donor was a 50-year-old female..
Read MoreAbstract Background To compare the safety and efficacy of low-dose anticoagulation (LA) with that of standardized dose anticoagulation (SA) for patients supported with extracorporeal membrane oxygenation (ECMO). Methods PubMed, MEDLINE,..
Read MoreAbstract Extracorporeal life support (ECLS) for severe respiratory failure has seen an exponential growth in recent years. Extracorporeal membrane oxygenation (ECMO) and extracorporeal CO2 removal (ECCO2R) represent two modalities that can..
Read MoreAbstract Although de‐airing procedures are commonly performed during cardiac surgery, use of these procedures is not necessarily based on evidence. Uncertainly remains around the size of bubbles that can be..
Read MoreAbstract Introduction The role of intra-aortic balloon pumps (IABP) in high-risk patients undergoing (CABG) surgery remains controversial. We report the 5-year experience from a new Australian centre. Methods We retrospectively analysed..
Read MoreAntecedent ACE-inhibition, inflammatory response, and cardiac surgery associated acute kidney injury
Abstract Cardiopulmonary bypass (CPB) may trigger organs damage, including kidney injury, due to a massive cytokine release. In this observational, prospective study, we analyzed the possible impact of chronic treatment..
Read MoreAbstract Background Acute Kidney Injury (AKI) adversely affects outcomes after cardiac surgery. A major mediator of AKI is the activation of leukocytes through exposure to the cardiopulmonary bypass circuit. We..
Read MoreAbstract Despite advances in medical technology, the mortality rate for severe acute respiratory distress syndrome (ARDS) remains high at around 40% []. In recent years, multiple studies, systematic reviews, and..
Read MoreAbstract Background: Acute type A aortic dissection (ATAAD) has a high risk of perioperative bleeding and often requires extensive blood product infusions. Analysis of the changes in coagulation and fibrinolysis..
Read MoreAbstract Objectives: Cardiac postoperative cognitive dysfunction (c-POCD) is a common complication. This article established a nomogram by analyzing preoperative and intraoperative data to help identify high-risk patients and take effective..
Read MoreAbstract CytoSorb is a promising tool to treat severe inflammatory status with multiple mechanisms in the acute care setting. Its effect on drugs is, however, poorly documented in vivo, although..
Read MoreAbstract Objectives: Several studies have reported prone positioning of nonintubated patients with coronavirus diseases 2019–related hypoxemic respiratory failure. This systematic review and meta-analysis evaluated the impact of prone positioning on..
Read MoreAbstract OBJECTIVES Chronic kidney disease (CKD) is a key risk factor in patients undergoing transcatheter aortic valve implantation (TAVI) or surgical aortic valve replacement (SAVR). We analysed the impact of..
Read MoreAbstract CORONAVIRUS DISEASE 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, is a complex multisystem disorder primarily characterized by pulmonary involvement. Although lung injury leading to..
Read MoreAbstract Background: The aim of this study was to evaluate the ipsilateral lower extremity (ILE) outcomes of patients who underwent bedside angiography via the distal perfusion catheter while on femoral..
Read MoreAbstract Moderate physical exercise is associated with an irrefutable reduction in cardiac morbidity and mortality. The current guidelines recommend at least 150 min of moderate exercise or 75 min of..
Read MoreAbstract Cardiogenic shock (CS) remains the leading cause of death in patients hospitalised with acute myocardial infarction with mortality as high as 40%–50% prior to hospital discharge. The failure of..
Read MoreAbstract Twenty years after the introduction of alcohol septal ablation (ASA) for the treatment of obstructive hypertrophic cardiomyopathy, the arrhythmogenicity of the ablation scar appears to be overemphasized. When systematically..
Read MoreAbstract The mechanisms responsible for the positive and unexpected cardiovascular effects of sodium-glucose cotransporter-2 inhibitors and glucagon-like peptide-1 receptor agonists in patients with type 2 diabetes remain to be defined...
Read MoreAbstract A man in his 70s with a history of multiple prior ST-segment elevation myocardial infarctions (STEMIs) and squamous cell carcinoma of the lung with metastatic disease to the brain..
Read MoreAbstract The coronavirus disease 2019 (COVID-19) pandemic has impacted people of all ages. Although children have been largely spared from the direct impact of the pandemic and only a minority..
Read MoreAbstract In this interview, the renowned cardiac surgeon Thierry Carrel explains what happens when the heart becomes weak, what the different treatment options are and why the new approach from..
Read MoreAbstract with current methods of is still incomplete , , . Several studies have shown that hyperkalemic solution may lead to cell injury , . Adenosine-lidocaine-magnesium (ALM) is a new normokalemic, “polarizing” method of cardioplegia that..
Read MoreAbstract Importance Approximately 15% of patients undergoing cardiac surgery receive frozen plasma (FP) for bleeding. Four-factor prothrombin complex concentrates (PCCs) have logistical and safety advantages over FP and may be a..
Read MoreAbstract Objective The safety of minimally invasive mitral valve surgery (MIMVS) in elderly patients is still debated. Our objective was to perform a systematic review and meta-analysis of studies comparing..
Read MoreAbstract Patients who receive venovenous extracorporeal membrane oxygenation (VV ECMO) support upon failure of invasive mechanical ventilation (IMV) and other adjuncts, including low tidal volume, prone positioning, adjusted positive end-expiratory pressure, and..
Read MoreAbstract Space travel is often touted as the pinnacle of human progress, with the current missions to Mars an example thereof []. For those living in Lower-and-Middle-Income Countries (LMICs), this..
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