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The Effectiveness of Levosimendan on Veno-Arterial Extracorporeal Membrane Oxygenation Management and Outcome: A Systematic Review and Meta-Analysis

Abstract Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) provides a temporary support system for patients with cardiogenic shock refractory to conventional medical therapies. It has been reported that levosimendan may facilitate VA-ECMO..

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Time course of risk factors associated with mortality of 1260 critically ill patients with COVID‑19 admitted to 24 Italian intensive…

Abstract Purpose: To evaluate the daily values and trends over time of relevant clinical, ventilatory and laboratory parameters during the intensive care unit (ICU) stay and their association with outcome..

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Women leaders in Cardiology. Contemporary profile of the WHO European region

Abstract Aims Women’s participation is steadily growing in medical schools, but they are still not sufficiently represented in cardiology, particularly in cardiology leadership positions. We present the contemporary distribution of..

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Multisite Veno-Venous Cannulation for Neonates and Nonambulatory Children

Abstract OBJECTIVES:  Neonates with respiratory failure are ideally supported with veno-venous rather than veno-arterial extracorporeal membrane oxygenation due to the reduced rate of neurologic complications. However, the proportion of neonates..

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Novel Brain Protection Method for Zone 0 Endovascular Aortic Repair with Selective Cerebral Perfusion

Abstract Objective: Zone 0 thoracic endovascular aortic repair (TEVAR) is associated with a high incidence of cerebral infarction mostly due to the embolic shower of a plaque from the aortic arch..

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Extracorporeal Membrane Oxygenation (ECMO) – Time is of the Essence!

Abstract Extra-corporeal membrane oxygenation (ECMO) is growing in adoption and popularity, as demonstrated by the international registry maintained by the Extracorporeal Life Support Organization (ELSO). While initially an adaptation of..

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Heparin beyond anti-coagulation

Abstract Heparin has served as a mainstream  for over eight decades. Clinically heparin-derived compounds significantly contribute to prevention and treatment of thrombotic events complicated in numerous medical conditions such as ,  and  processes. Moreover..

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RotaFlow and CentriMag Extracorporeal Membrane Oxygenation Support Systems as Treatment Strategies for Refractory Cardiogenic Shock

Abstract Background RotaFlow and Levitronix CentriMag veno-arterial extracorporeal membrane oxygenation (ECMO) support systems have been investigated as treatment for refractory cardiogenic shock (CS). Methods Between 2004 and 2012, 119 consecutive..

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Volatile Versus Intravenous Anesthetics in Cardiac Anesthesia: a Narrative Review

Abstract Purpose of the Review The present review addresses clinicians and gives an overview about the experimental rationale for pharmacological conditioning associated with volatile anesthetics, opioids, and propofol; the current..

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Pulsatility protects the endothelial glycocalyx during extracorporeal membrane oxygenation

Abstract Background Pulsatile flow protects vital organ function and improves microcirculatory perfusion during extracorporeal membrane oxygenation (ECMO). Studies revealed that pulsatile shear stress plays a vital role in microcirculatory function..

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Improving Formative Feedback in the Operating Room Setting

Abstract Problem:  Formative feedback, which is given in an ongoing fashion during the learning process, is fundamental to clinical education. However, dissatisfaction with formative feedback among residents is common. Difficulties..

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European registry of type A aortic dissection (ERTAAD) - rationale, design and definition criteria

Abstract Background Acute Stanford type A aortic dissection (TAAD) is a life-threatening condition. Surgery is usually performed as a salvage procedure and is associated with significant postoperative early mortality and..

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Morphologic variants of the Cerebral Arterial Circle on computed tomographic angiography (CTA): a large retrospective study

Abstract Purpose To confirm and illustrate the great variability of morphology of the Cerebral Arterial Circle (CAC)—also commonly called “Circle of Willis”—in current clinical Computed Tomography Angiography (CTA) practice. Methods..

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An overview of human pericardial space and pericardial fluid

Abstract The pericardium is a double-layered fibro-serous sac that envelops the majority of the surface of the heart as well as the great vessels. Pericardial fluid is also contained within..

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Can Heparin-Coated ECMO Cannulas Induce Thrombocytopenia in COVID-19 Patients?

Abstract Extracorporeal membrane oxygenation (ECMO) is often used in the management of COVID-19-related severe respiratory failure. We report the first case of a patient with COVID-19-related ARDS on ECMO support..

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The role of hydrocortisone pre-treatment in decreasing side effects of protamine sulfate administration during cardiac surgery: a randomised controlled trial

Abstract Background One of the challenges during cardiac surgery is to keep patients fully anticoagulated during the  time and reversing  at the end of surgery. For that purpose, heparin and its approved..

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Adverse Outcomes Prediction for Congenital Heart Surgery: A Machine Learning Approach

Abstract Objective: Risk assessment tools typically used in congenital heart surgery (CHS) assume that various possible risk factors interact in a linear and additive fashion, an assumption that may not..

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Risk-adjusted analysis of long-term outcomes after on- versus off-pump coronary artery bypass grafting

Abstract     OBJECTIVES Recent data suggested that off-pump coronary artery bypass (OPCAB) may carry a higher risk for mortality in the long term when compared to on-pump coronary artery..

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Results of a prospective follow-up study after type A aortic dissection repair: a high rate of distal aneurysmal evolution and…

Abstract     OBJECTIVES We investigated the anatomical evolution of residual aortic dissection after type A repair and factors associated with poor prognosis at a high-volume aortic centre. METHODS Between..

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Relatively Benign yet a Reversible Cause of Dilated Cardiomyopathy

Abstract Arrhythmia-induced cardiomyopathy secondary to frequent ventricular premature contractions is a well-studied phenomenon; however, there is a paucity of data showing a similar association with frequent atrial premature contractions (APCs)...

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The role of temporary mechanical circulatory support in an effective surgical treatment of a left ventricular aneurysm and a ventricular…

Referring to the discussion on effective methods of treatment for patients with a post-infarction left ventricular aneurysm and a ventricular septal defect (VSD) [1], we present the case of a..

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Association of perfusate oxygenation with cardiovascular disorder in tetralogy of fallot children: A nested case–control study

Abstract Background Little is known regarding whether hyperoxic reoxygenation was associated with higher risk of cardiovascular disorder following tetralogy of Fallot repair. Methods We performed a nested case–control study among..

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A simplified delivery frozen elephant trunk technique to reduce circulatory arrest time in hybrid aortic arch surgery

Abstract A simplified delivery technique for the frozen elephant trunk procedure allows the distal suture to be performed on a perfused and loaded aorta in moderate hypothermia—or even normothermia—reducing circulatory..

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Mitral and tricuspid annuloplasty ring dehiscence, a story yet to be told

Abstract The goals of mitral valve (MV) and tricuspid valve (TV) repair are to restore leaflet motion, to increase leaflet coaptation and to stabilize the annulus with preservation of an..

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Global and regional right ventricular mechanics in repaired tetralogy of Fallot with chronic severe pulmonary regurgitation: a three-dimensional echocardiography study

Abstract Background Data about the right ventricular (RV) mechanics adaptation to volume overload in patients with repaired tetralogy of Fallot (rToF) are limited. Accordingly, we sought to assess the mechanics..

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Role of Acquired Von Willebrand Syndrome in Patients Treated Using Impella RP® Devices: A Retrospective Cohort Study

Abstract Background: Axial flow pumps are standard treatment in cases of cardiogenic shock and high-risk interventions in cardiology and cardiac surgery, although the optimal anticoagulation strategy remains unclear. We evaluated whether..

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Patient blood management in cardiac surgery: The “Granducato algorithm”

Abstract Background Patients undergoing cardiac surgery are subject to severe alterations of the coagulation system. The four cardiac surgery centers in Tuscany (Italy) structured and shared an algorithm (Granducato Patient..

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Neurologic Complications and Neuromonitoring on ECMO

Abstract Extracorporeal membrane oxygenation is challenged by several potential complications. Adverse neurologic events such as intracranial hemorrhages, strokes, seizures, and brain death are among the most detrimental and even catastrophic..

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A Narrative Review of Nutrition Therapy in Patients Receiving Extracorporeal Membrane Oxygenation

Abstract The use of extracorporeal membrane oxygenation (ECMO) in patients with severe cardiorespiratory failure has seen significant growth in the last decade. Despite this, there is paucity of data surrounding..

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An Extracorporeal Membrane Oxygenation First Strategy in COVID-19 Acute Respiratory Distress Syndrome

Abstract COVID-19 can be associated with acute respiratory distress syndrome (ARDS) which increases the likelihood of morbidity and mortality. Ventilator-induced lung injury (VLI) is a known complication of mechanical ventilation (MV) and..

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