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Obesity as a Risk Factor for Failure to Wean from ECMO: A Systematic Review and Meta-Analysis

Abstract Purpose. Obesity has been associated with an increased risk of respiratory complications and other systemic illnesses. Respiratory dynamics in an obese patient, combined with modified lung physiology of ARDS,..

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Comparison of Hemostatic Changes in Pump-driven Extracorporeal Carbon Dioxide Removal and Venovenous Extracorporeal Membrane Oxygenation

Abstract Extracorporeal carbon dioxide removal (ECCO2R) has gained widespread use as a supposedly less invasive alternative for hypercapnic respiratory failure besides venovenous extracorporeal membrane oxygenation (VV ECMO). Despite technological advances,..

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Right Ventricular Global Longitudinal Strain as a Predictor of Acute and Early Right Heart Failure Post Left Ventricular Assist Device…

Abstract Early right heart failure (RHF) occurs in up to 40% of patients following left ventricular assist device (LVAD) implantation and is associated with increased morbidity and mortality. The most recent..

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Major Bleeding and Thrombosis Events in COVID-19 Versus Influenza Patients Requiring Extracorporeal Membrane Oxygenation

Abstract Initial reports described a hypercoagulable state and an increased risk of thrombosis in patients who tested positive for SARS-CoV-2. Infected patients with severe acute respiratory distress syndrome in the setting of..

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Network meta-analysis comparing blood cardioplegia, Del Nido cardioplegia and custodiol cardioplegia in minimally invasive cardiac surgery

Abstract Introduction Minimally invasive cardiac surgery has been evolving, with the intention of reducing surgical trauma, improve cosmesis and patient satisfaction. Single dose, crystalloid cardioplegia such as Del Nido cardioplegia..

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Study shows young, healthy adults died from COVID-19 due to ECMO shortage

Abstract Nearly 90% of COVID-19 patients who qualified for, but did not receive, ECMO (extracorporeal membrane oxygenation) due to a shortage of resources during the height of the pandemic died..

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Survival benefit of extracorporeal membrane oxygenation in severe COVID-19: a multi-centre-matched cohort study

Abstract Purpose Extracorporeal membrane oxygenation (ECMO) has become an established therapy for severe respiratory failure in coronavirus disease 2019 (COVID-19). The added benefit of receiving ECMO in COVID-19 remains uncertain...

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Impact of Portable Normothermic Blood-Based Machine Perfusion on Outcomes of Liver Transplant

Abstract Importance  Ischemic cold storage (ICS) of livers for transplant is associated with serious posttransplant complications and underuse of liver allografts. Objective  To determine whether portable normothermic machine perfusion preservation of livers..

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A systematic review of the evidence supporting post-operative antithrombotic use following cardiopulmonary bypass in children with CHD

Abstract Objectives:To determine the optimal antithrombotic agent choice, timing of initiation, dosing and duration of therapy for paediatric patients undergoing cardiac surgery with cardiopulmonary bypass. Methods:We used PubMed and EMBASE..

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A Review of Pulmonary Arterial Hypertension Treatment in Extracorporeal Membrane Oxygenation: A Case Series of Adult Patients

Abstract Background: Little data is published describing the use of medications prescribed for pulmonary arterial hypertension (PAH) in patients receiving extracorporeal membrane oxygenation (ECMO). Even though many patients with PAH..

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The effect of perioperative hemadsorption in patients operated for acute infective endocarditis—A randomized controlled study

Abstract Patients operated for infective endocarditis (IE) are at high risk of developing an excessive systemic hyperinflammatory state, resulting in systemic inflammatory response syndrome and septic shock. Hemoadsorption (HA) by..

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Intraoperative transfusion practices and perioperative outcome in the European elderly: A secondary analysis of the observational ETPOS study

Abstract The demographic development suggests a dramatic growth in the number of elderly patients undergoing surgery in Europe. Most red blood cell transfusions (RBCT) are administered to older people, but..

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Analysis of Dynamic Changes in Cognitive Workload During Cardiac Surgery Perfusionists′ Interactions With the Cardiopulmonary Bypass Pump

Abstract Objective This novel preliminary study sought to capture dynamic changes in heart rate variability (HRV) as a proxy for cognitive workload among perfusionists while operating the cardiopulmonary bypass (CPB)..

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Extracorporeal membrane oxygenation for COVID-19 during first and second waves

Abstract COVID-19 has ravished the world, with secondary consequences that are not yet possible to estimate. WHO and the European Extracorporeal Life Support Organization (ELSO) recommended extracorporeal membrane oxygenation (ECMO)..

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The effect of retrograde autologous priming on intraoperative blood product transfusion in coronary artery bypass grafting

Abstract Introduction: Retrograde autologous priming (RAP) of the cardiopulmonary bypass (CPB) circuit could reduce the degree of haemodilution associated with priming with acellular solutions. However, there is no strong evidence to..

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A mock circulation loop to evaluate differential hypoxemia during peripheral venoarterial extracorporeal membrane oxygenation

Abstract Introduction Peripheral veno-arterial extracorporeal membrane oxygenation (VA ECMO) creates a retrograde flow along the aorta competing with the left ventricle (LV) in the so-called ‘mixing zone’ (MZ). Detecting it..

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ECMO en SDRA: puntos clave en la indicación y en el abordaje asistencial

Abstract El uso de la técnica de oxigenación mediante membrana extracorpórea (ECMO), en su configuración venovenosa (V-V), en pacientes con síndrome de distrés respiratorio agudo (SDRA) ha aumentado en los..

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Utilization of EKOS in Patients With Pulmonary Embolism

Abstract Objective: Current guidelines recommend utilization of catheter-directed thrombolysis systems for management of patients with submassive pulmonary embolism (PE) who have relative contraindications to systemic thrombolysis. Evidence from previous trials have..

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Conventional Versus Minimally Invasive Aortic Valve Replacement Surgery: A Systematic Review, Meta-Analysis, and Meta-Regression

Abstract Objective: To assess the potential benefits of minimally invasive aortic valve replacement (MIAVR) compared with conventional AVR (CAVR) by examining short-term outcomes.  Methods: A systematic search identified randomized trials comparing MIAVR..

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ECMO During Respiratory Pandemics: Past, Present, and Future

Abstract The role of extracorporeal membrane oxygenation (ECMO) in the management of severe acute respiratory failure, including the acute respiratory distress syndrome, has become better defined in recent years in..

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Impact of extracorporeal membrane oxygenation service on burnout development in intensive care units. A national cross-sectional study in eight intensive…

Abstract Objectives This study aimed at investigating the effects of an extracorporeal membrane oxygenation (ECMO) service, on Burnout syndrome (BOS) development in the intensive care unit (ICU). Design We conducted..

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Longitudinal Trends in Bleeding Complications on Extracorporeal Life Support Over the Past Two Decades—Extracorporeal Life Support Organization Registry Analysis

Abstract Objectives:  Data about inhospital outcomes in bleeding complications during extracorporeal life support (ECLS) have been poorly investigated. Design:  Retrospective observational study. Setting:  Patients reported in Extracorporeal Life Support Organization..

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Association of urine output during cardiopulmonary bypass and postoperative acute kidney injury in patients undergoing coronary artery bypass graft

Abstract Introduction Acute kidney injury (AKI) is a common complication in patients undergoing coronary artery bypass graft (CABG) surgery and is associated with significant morbidity and mortality. We investigated the..

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Outcomes by Cannulation Methods for Venovenous Extracorporeal Membrane Oxygenation during COVID-19: A Multicenter Retrospective Study

Abstract Purpose To determine if a cannulation method for venovenous extracorporeal membrane oxygenation (V-V ECMO) is related to patient outcome. Methods A retrospective, multi-center study of adult patients (≥18 years..

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Effect of Intra-arrest Transport, Extracorporeal Cardiopulmonary Resuscitation, and Immediate Invasive Assessment and Treatment on Functional Neurologic Outcome in Refractory Out-of-Hospital…

Abstract Importance  Out-of-hospital cardiac arrest (OHCA) has poor outcome. Whether intra-arrest transport, extracorporeal cardiopulmonary resuscitation (ECPR), and immediate invasive assessment and treatment (invasive strategy) is beneficial in this setting remains uncertain...

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Coagulation activation during extracorporeal membrane oxygenation (ECMO)

Abstract Introduction  (ECMO) can be life-saving, but suffers from  in the circuit with associated risks of  occlusion,  and . The formation of thrombin is the key step to thrombus formation and two factors are..

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Impella Management for the Cardiac Intensivist

Abstract The Impella mechanical circulatory support (MCS) system is a catheter-based continuous flow cardiac assist device that is widely used in the treatment of cardiogenic shock in medical and surgical cardiac intensive..

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A review of ECMO for cardiac arrest

Abstract Cardiac arrest is an important public health concern, affecting an estimated 356,500 people in the out-of-hospital setting and 209,000 people in the in-hospital setting each year. The causes of..

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Impact of comorbidities on older patients undergoing open heart surgery

Abstract Background  The number of elderly patients undergoing cardiac surgery is increasing. Age greater than 80 years has been identified as a strong independent risk factor for short- and long-term..

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ECMO in Cardiac Arrest: A Narrative Review of the Literature

Abstract Cardiac arrest (CA) is a frequent cause of death and a major public health issue. To date, conventional cardiopulmonary resuscitation (CPR) is the only efficient method of resuscitation available..

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