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Interprofessional model on speaking up behaviour in healthcare professionals: a qualitative study

Abstract Objectives Despite training and the recognition that speaking up can mitigate harm to patients and save lives, healthcare professionals do not consistently speak up when they have patient safety concerns...

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Reduced sevoflurane loss during cardiopulmonary bypass when using a polymethylpentane versus a polypropylene oxygenator

Abstract Purpose: The goal of this investigation was to examine the influence of two oxygenators with different membranes, made of either polypropylene (PPL) or polymethylpentane (PMP), on the plasma concentration of..

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Pediatric Extracorporeal Membrane Oxygenation (ECMO) Transport in a Developing Nation: A Single Center Experience

Abstract Extracorporeal membrane oxygenation (ECMO) support requires skills that can only be found in specialized centers. The number of patients annually supported with ECMO is positively associated with the survival..

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Starting and Sustaining an Extracorporeal Membrane Oxygenation Program

Abstract The use of extracorporeal membrane oxygenation (ECMO) is growing rapidly in all patient populations, especially adults for both acute lung or heart failure. ECMO is a complex, high risk,..

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Extracorporeal membrane oxygenation during pregnancy and peripartal. An international retrospective multicenter study

Abstract Introduction Extracorporeal Membrane Oxygenation (ECMO) may be used in the setting of pregnancy or the peripartal period, however its utility has not been well-characterized. This study aims to give..

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Perfusion of brain and viscera using modified retrograde cerebral perfusion for aortic arch surgery

Abstract Anterograde or retrograde cerebral perfusion can protect the brain from ischemic injury during hypothermic circulatory arrest (HCA), but neither type of perfusion provides blood flow to the abdominal viscera...

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Clinical impact of del Nido cardioplegia in adult cardiac surgery: A prospective randomized trial

Abstract Objective The study objective was to assess the benefits of del Nido cardioplegia compared with cold blood cardioplegia solution in terms of myocardial protection during adult cardiac surgery. Methods..

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Endothelial Dysfunction in SARS-CoV-2 Infection

Abstract One of the hallmarks of the SARS-CoV-2 infection has been the inflammatory process that played a role in its pathogenesis, resulting in mortality within susceptible individuals. This uncontrolled inflammatory..

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The problem with making Safety-II work in healthcare

Abstract Patient safety is typically assessed by the frequency of adverse events or incidents, which means we seek to determine safety by its absence rather than its presence. The Safety-II perspective..

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Extracorporeal membrane oxygenation in children: An update of a single tertiary center 11-Year experience from Croatia

Abstract Introduction: Extracorporeal membrane oxygenation (ECMO) is an important treatment option for organ support in respiratory insufficiency, cardiac failure, or as an advanced tool for cardiopulmonary resuscitation. Reports on pediatric..

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Early Albumin Exposure After Cardiac Surgery

Abstract Objectives To determine whether the early use of  after cardiac surgery in the first 24 hours in the intensive care unit (ICU) is associated with reduced mortality. Design A single-center..

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How to manage anticoagulation during extracorporeal membrane oxygenation

Abstract Extracorporeal membrane oxygenation (ECMO) use is increasing worldwide, driven by device simplification and increasing need during the coronavirus disease 2019 (COVID-19) pandemic, while bleeding and thrombotic events remain a..

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Hemoperfusion: technical aspects and state of the art

Abstract Background: Blood purifcation through the removal of plasma solutes by adsorption to beads of charcoal or resins contained in a cartridge (hemoperfusion) has a long and imperfect history. Developments..

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Gelatin and the risk of acute kidney injury after cardiac surgery

Abstract Background Gelatin has been used as a plasma volume expander because of its ability to preserve intravascular volume more effectively than crystalloids. However, gelatin may have detrimental effects on..

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Outcomes with Direct and Indirect Thrombin Inhibition during Extracorporeal Membrane Oxygenation for COVID-19

Abstract Anticoagulation during extracorporeal membrane oxygenation (ECMO) for Coronovirus Disease 2019 (COVID-19) can be performed by direct or indirect thrombin inhibitors but differences in outcomes with these agents are uncertain...

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Long-term outcomes of patients undergoing mechanical versus bioprosthetic aortic root replacement

Abstract Background We evaluated the impact of valve type (mechanical vs. bioprosthetic) on survival after aortic root replacement (ARR). Methods In a propensity-matched analysis, we evaluated consecutive operations from 2010..

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Tocilizumab Accelerates Recovery in Patients With Severe COVID-19 Pneumonia on Venovenous Extracorporeal Membrane Oxygenation

Abstract Tocilizumab is known to improve outcomes in patients with severe coronavirus disease 2019 (COVID-19) pneumonia. However, little is known about its utility in patients with COVID-19 who require respiratory..

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Extracorporeal Membrane Oxygenation Circuits in Parallel for Refractory Hypoxemia in COVID-19: A Case Series

Abstract Refractory hypoxemia despite the use of extracorporeal membrane oxygenation (ECMO) for coronavirus disease 2019 (COVID-19)–related acute respiratory distress syndrome remains a challenging problem. A single ECMO circuit may not..

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Direct Innominate Artery Cannulation versus Side Graft for Selective Antegrade Cerebral Perfusion during Aortic Hemiarch Replacement

Abstract Background Selective antegrade cerebral perfusion (SACP) has become our preferred method for cerebral protection during open arch cases. While the initial approach involved sewing a graft to the innominate..

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Continuous renal replacement therapy in patients treated with extracorporeal membrane oxygenation

Abstract Extracorporeal membrane oxygenation (ECMO) is a life-saving therapy utilized for patients with severe life-threatening cardiorespiratory failure. Patients treated with ECMO are among the most severely ill encountered in critical..

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Pulmonary embolism response team: A multidisciplinary approach to pulmonary embolism treatment. Polish PERT Initiative Report

Abstract Background:A pulmonary embolism response team (PERT) is a multidisciplinary team established to improve clinical care for patients with pulmonary embolism (PE). However, data regarding detailed institutional experience and clinical..

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Perioperative Continuous Noninvasive Cardiac Output Monitoring in Cardiac Surgery Patients by a Novel Capnodynamic Method

Abstract Objectives To test the clinical performance of a novel continuous noninvasive cardiac output (CO) monitoring based on expired carbon dioxide kinetics in cardiac surgery patients. Design A prospective feasibility..

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Brain death: a clinical overview

Abstract Brain death, also commonly referred to as death by neurologic criteria, has been considered a legal definition of death for decades. Its determination involves many considerations and subtleties. In..

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Economic Evaluation of National Patient Blood Management Clinical Guidelines in Cardiac Surgery

Abstract Objectives To the best of our knowledge, no published clinical guidelines have ever undergone an economic evaluation to determine whether their implementation represented an efficient allocation of resources. Here,..

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When to Refer for SAVR in an Era of Expanding TAVR Use?

Abstract As transcatheter aortic valve replacement (TAVR) expands in use as an alternative to surgical AVR (SAVR) for patients with severe symptomatic aortic valve stenosis across a wide spectrum of..

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Tracheostomy Practices and Outcomes in Patients With COVID-19 Supported by Extracorporeal Membrane Oxygenation: An Analysis of the Extracorporeal Life Support…

Abstract Objectives:  The use of extracorporeal membrane oxygenation (ECMO) in patients with COVID-19 has been supported by major healthcare organizations, yet the role of specific management strategies during ECMO requires..

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Utility of D-dimers in COVID-19 Patients Requiring Extracorporeal Membrane Oxygenation

Abstract A retrospective study was performed examining the trend of inflammatory markers, including D-dimers, in 29 COVID-19 patients requiring veno-venous (VV) extracorporeal membrane oxygenation (ECMO) support. We observed that COVID-19..

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The emerging concept of fluid tolerance: A position paper

Abstract Fluid resuscitation is a core component of emergency and critical care medicine. While the focus of clinicians has largely been on detecting patients who would respond to fluid therapy, relatively..

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Histidine–tryptophan–ketoglutarate solution versus multidose cardioplegia for myocardial protection in cardiac surgeries: a systematic review and meta-analysis

Abstract Background Surgical procedures in the heart requires protection of the heart from ischemia–reperfusion injury. Cardioplegia is the primary myocardial protective method in use. Histidine–tryptophan–ketoglutarate (HTK) solution is an intracellular..

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Simultaneous electrical online estimation of changes in blood hematocrit and temperature in cardiopulmonary bypass

Abstract Two equations have been developed from multi-frequency measurements of blood impedance Zb for a simultaneous electrical online estimation of changes in blood hematocrit ΔH [%] and temperatures ΔT [K] in cardiopulmonary bypass (CPB). Zb of fixed blood..

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