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Efficacy and Safety of Extracorporeal Membrane Oxygenation in Patients under Mechanical Ventilation with COVID-19 and Severe Acute Respiratory Distress Syndrome:…

Abstract We aimed to assess the efficacy and safety of extracorporeal membrane oxygenation (ECMO) in patients under mechanical ventilation with COVID-19 and severe acute respiratory distress syndrome (ARDS). A systematic..

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Transfusion policy in pediatric extracorporeal membrane oxygenation patients: Less could be more

Abstract Objective To evaluate a restrictive transfusion policy of red blood cells (RBC) and platelets in pediatric patients submitted to extracorporeal membrane oxygenation (ECMO). Methods Retrospective descriptive study of pediatric..

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Bivalirudin vs. heparin in paediatric and adult patients on extracorporeal membrane oxygenation: A meta-analysis

Abstract Aims Unfractionated heparin (UFH) has been the primary anticoagulant of choice on extracorporeal membrane oxygenation (ECMO). However, it is debatable whether bivalirudin (BIV), a direct thrombin inhibitor, may be..

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Predicting Mortality for Patients Eligible for Extracorporeal Membrane Oxygenation for COVID-19

Abstract During the coronavirus disease (COVID-19) pandemic, the number of patients eligible to receive extracorporeal membrane oxygenation (ECMO) has exceeded the availability of this resource-intensive therapy (). To maximize benefit,..

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Improving Trendelenburg position effectiveness by varying cardiopulmonary bypass flow

Abstract Introduction Trendelenburg position (TP) is used to transport gaseous emboli away from the cerebral region during cardiac surgery. However, TP effectiveness has not been fully considered when combined with..

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The novel ProtekDuo ventricular assist device: Configurations, technical aspects, and present evidence

Abstract The ProtekDuo, single site dual lumen cannula can be used in a multitude of configurations. In the medical literature, the ProtekDuo is described as right ventricular assist device (RVAD),..

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Perspectives in Training and Professional Practice of Cardiac Surgery in Latin America

Abstract Introduction: There is a lack of information about cardiac surgery training and professional practice in Latin American (LATAM) countries. This study is the first comparative analysis of cardiac surgical..

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Effect of Hemadsorption Therapy in Critically Ill Patients with COVID-19 (CYTOCOV-19): A Prospective Randomized Controlled Pilot Trial

Abstract Introduction: Immunomodulatory therapies have shown beneficial effects in patients with severe COVID-19. Patients with hypercytokinemia might benefit from the removal of inflammatory mediators via hemadsorption. Methods: Single-center prospective randomized trial at..

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Joint Recommendations From The Latin American Association of Cardiac and Endovascular Surgery (LACES) and The Cardiovascular Anesthesia Committee of The…

Abstract Introduction: Since the coronavirus disease 2019 (COVID-19) pandemic, cardiac surgeries in patients with previous infection by COVID-19 were suspended or postponed, which led to surgeries performed in patients with..

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Variable Sequestration of Antifungals in an Extracorporeal Membrane Oxygenation Circuit

Abstract Fungal infections are common and frequently associated with clinical failure in patients receiving extracorporeal membrane oxygenation (ECMO). Antifungal drugs have physicochemical characteristics associated with a higher likelihood of sequestration..

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HIPEC increases cancer survival rates but lacks regional awareness

Abstract Hyperthermic intraperitoneal chemotherapy (HIPEC), a new stage IV cancer treatment method conceived about 20 years ago, is a global game-changer in improving survival rates, however, not many patients in..

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Ejection Fraction Improvement Following Contemporary High-Risk Percutaneous Coronary Intervention: RESTORE EF Study Results

Abstract Background Despite many reports of clinical outcomes in patients undergoing high-risk percutaneous coronary intervention (HRPCI) with hemodynamic support, little is known about whether this approach improves left ventricular ejection..

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The platelet in cardiopulmonary bypass

Abstract Platelets are the smallest of the blood cells and are known to be activated during cardiopulmonary bypass. They play a role in many associated complications. Both quantitative and qualitative..

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Application of Adsorptive Blood Purification Techniques during Cardiopulmonary Bypass in Cardiac Surgery

Abstract By reason of surgical demand, the majority of cardiovascular procedures still depend on the use of cardiopulmonary bypass (CPB). Due to the nonphysiological state of CPB, it can cause..

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Impact of various periods of perfusion-pause and reperfusion on the severity of myocardial injury in the langenodorff model

Abstract Background To explore impact of various periods of ischemia and reperfusion on the severity of myocardial injury. Methods Langendorff model of isolated cardiac perfusion system was established in 56..

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End-stage Renal Disease and Long-term Survival Among Survivors of Extracorporeal Membrane Oxygenation.

Abstract We aimed to investigate the prevalence and associated factors of newly diagnosed end-stage renal disease (ESRD) requiring renal-replacement therapy (RRT) among survivors of extracorporeal membrane oxygenation (ECMO) and determine..

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High-Target Versus Low-Target Blood Pressure Management During Cardiopulmonary Bypass to Prevent Cerebral Injury in Cardiac Surgery Patients

Abstract Background: Cerebral injury is an important complication after cardiac surgery with the use of cardiopulmonary bypass. The rate of overt stroke after cardiac surgery is 1% to 2%, whereas..

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Liberation from Mechanical Ventilation Before Decannulation from Venovenous Extracorporeal Life Support in Severe COVID-19 Acute Respiratory Distress Syndrome

Abstract The coronavirus disease 2019 (COVID-19) pandemic has been associated with the significant use of venovenous extracorporeal membrane oxygenation (VVECMO) globally. Identifying strategies to optimize care is essential to improving..

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The role of extracorporeal membrane oxygenation in COVID-19

Abstract An extracorporeal membrane oxygenation (ECMO) program is an important component in the management of patients with COVID-19, but it is imperative to implement a system that is well-supported by..

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Comparison of left ventricular unloading strategies on venoarterial extracorporeal life support

Abstract OBJECTIVES Our goal was to compare the haemodynamic effects of different mechanical left ventricular (LV) unloading strategies and clinical outcomes in patients with refractory cardiogenic shock supported with venoarterial..

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Five-Year Outcomes in Patients With Fully Magnetically Levitated vs Axial-Flow Left Ventricular Assist Devices in the MOMENTUM 3 Randomized Trial

Abstract Importance  Although durable left ventricular assist device (LVAD) therapy has emerged as an important treatment option for patients with advanced heart failure refractory to pharmacological support, outcomes, including survival, beyond..

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The outcomes of ultrafiltration in on-pump versus off-pump coronary artery bypass grafting in patients with renal impairment

Abstract Objective In chronic kidney disease (CKD), using cardiopulmonary bypass (CPB) may contribute to renal dysfunction. Off-pump coronary artery bypass grafting (OPCAB) is one technique that preserved renal function, but..

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Delivering optimal renal replacement therapy to critically ill patients with acute kidney injury

Abstract Critical illness is often complicated by acute kidney injury (AKI). In patients with severe AKI, renal replacement therapy (RRT) is deployed to address metabolic dysfunction and volume excess until..

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The relationship between antithrombin administration and inflammation during veno-venous ECMO

Abstract Veno-venous Extracorporeal Membrane Oxygenation (ECMO) is used in the most severe cases of respiratory failure and further exacerbates the patients’ inflammatory status. Antithrombin is supplemented during ECMO for its..

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In vitro comparison of spatiotemporal fibrin clot formation dynamics in plasma treated with different protamine-heparin ratios

Abstract Introduction Our study aim was to explore how different protamine-heparin ratios impacted enzymatic coagulation and acellular fibrin clot growth in plasma using an in vitro model. We hypothesized that..

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Outcome of type and screen versus crossmatch in cardiovascular surgery patients: A comparative study

Abstract BACKGROUND: The need for an anti-human globulin (AHG) cross-match (XM) when the antibody screen (ABS) is negative is debatable and a matter of policy. AIM: (1) To compare the outcomes of..

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Effect of Different Blood Groups on Long-Term Outcomes of Surgical Revascularisation

Abstract Background  are considered to be associated with cardiovascular disease. Nonetheless, the definite effect of  on the clinical outcome of  (CABG) is still undetermined. We evaluated whether ABO blood groups can predict..

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Getting the best from the Heart Team: guidance for cardiac multidisciplinary meetings

Abstract The purpose of this document is to update the existing joint British Societies recommendations on multidisciplinary meetings (MDMs) published in 2015 to reflect changes in practice. We aim to..

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Inferior and Superior Vena Cava Saturation Monitoring After Neonatal Cardiac Surgery

Abstract OBJECTIVES:  Superior vena cava oxygen saturation (SVC O2) monitoring is well described for early detection of hemodynamic deterioration after neonatal cardiac surgery but inferior vena cava vein oxygen saturation (IVC O2) monitoring data..

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