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Retrograde Autologous Priming in Cardiac Surgery: Results From a Systematic Review and Meta-analysis

Abstract Background:  Retrograde autologous priming (RAP) before cardiopulmonary bypass (CPB) may minimize allogeneic red cell transfusion. We conducted a systematic review of the literature to examine the impact of RAP..

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Role of Intraoperative Transesophageal Echocardiography in Cardiac Surgery: an Observational Study

Abstract AIM  This study is based on the hypothesis that the routine use of transesophageal echocardiography in cardiac surgery will influence the surgical decision taken by the surgeon intra-operatively in..

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The correlation of post-operative acute kidney injury and perioperative anaemia in patients undergoing cardiac surgery with cardiopulmonary bypass

Abstract Background and objective Acute kidney injury (AKI) following cardiac surgery with cardiopulmonary bypass (CPB) is polyethiological clinical syndrome. During CPB haemodilution develops, which is useful in reducing the risk..

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Effect of high- versus low-volume saline administration on acute kidney injury after cardiac surgery

Abstract Background: Fluid resuscitation is critical to perioperative maintenance of adequate preload and cardiac output after cardiac surgery. Liberal use of saline, however, is reportedly associated with an increased risk of..

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Transient acute kidney injury after cardiac surgery does not independently affect postoperative outcomes

Abstract Background The objective of this study was to assess the incidence of in‐hospital acute kidney injury (AKI) after cardiac surgery by comparing preoperative baseline renal function with renal function..

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Fish Oil and Perioperative Bleeding

Abstract Background Fish oil is among the most common natural supplements for treatment of hypertriglyceridemia or prevention of cardiovascular disease. However, concerns about theoretical bleeding risk have led to recommendations..

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Association of Anaesthetists guidelines: cell salvage for peri‐operative blood conservation 2018

Abstract The use of cell salvage is recommended when it can be expected to reduce the likelihood of allogeneic (donor) red cell transfusion and/or severe postoperative anaemia. We support and..

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Urinary biomarkers predict advanced acute kidney injury after cardiovascular surgery

Abstract Background Acute kidney injury (AKI) after cardiovascular surgery is a serious complication. Little is known about the ability of novel biomarkers in combination with clinical risk scores for prediction..

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Impact of an inline extracorporeal membrane oxygenation hemofilter system in neonatal acute kidney injury

Abstract Extracorporeal membrane oxygenation (ECMO) is considered a recognized lifesaving support for patients with cardiorespiratory failure. Acute kidney injury (AKI) and fluid overload are significant morbidity factors resulting in serious..

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Urinary hypoxia: an intraoperative marker of risk of cardiac surgery-associated acute kidney injury

Abstract Background Acute kidney injury (AKI) is common after cardiac surgery and profoundly affects postoperative mortality and morbidity. There are no validated methods to assess risk of AKI intraoperatively. Methods..

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Clinical review: Interpretation of arterial pressure wave in shock states

Abstract In critically ill patients monitored with an arterial catheter, the arterial pressure signal provides two types of information that may help the clinician to interpret haemodynamic status better: the..

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Measuring fibrinolysis: from research to routine diagnostic assays

Abstract Summary Development and standardization of fibrinolysis methods have progressed more slowly than coagulation testing and routine high‐throughput screening tests for fibrinolysis are still lacking. In laboratory research, a variety..

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The level of urinary IL-18 in acute kidney injury after cardiopulmonary bypass

ABSTRACT This study investigated the diagnostic value of urinary interleukin-18 (uIL-18) in acute kidney injury (AKI) after cardiopulmonary bypass (CPB) in clinical practice. A total of 103 patients who underwent..

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Red Blood Cell Exosome Hemoglobin Content Increases After Cardiopulmonary Bypass and Mediates Acute Kidney Injury in an Animal Model

Abstract Objective Hemolysis, characterized by formation of free hemoglobin (Hb), occurs in patients undergoing cardiopulmonary bypass (CPB). However, there is no study of the dynamic changes in red blood cell..

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International consensus statement on the peri‐operative management of direct oral anticoagulants in cardiac surgery

Summary Despite current recommendations on the management of severe peri‐operative bleeding, there is no pragmatic guidance for the peri‐operative monitoring and management of cardiac surgical patients taking direct oral anticoagulants...

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Risk Assessment of Acute Kidney Injury Following Cardiopulmonary Bypass

Abstract Background Acute kidney injury (AKI) is a frequent and serious complication of cardiac surgery, associated with a high incidence of morbidity and mortality. Although the RIFLE criteria serve as..

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Management of Congenital Cardiac Surgery During COVID-19 Pandemic

Abstract The new coronavirus infection, which was first seen in China in late December, 2019 and eventually became a worldwide pandemic, poses a serious threat to public health. After a..

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Extra-corporeal membrane oxygenation for refractory cardiogenic shock after adult cardiac surgery: a systematic review and meta-analysis

Background Postcardiotomy cardiogenic shock (PCCS) refractory to inotropic support and intra-aortic balloon pump (IABP) occurs rarely but is almost universally fatal without mechanical circulatory support. In this systematic review and..

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A Review on Extracorporeal Membrane Oxygenation and Kidney Injury

Abstract Extracorporeal membrane oxygenation (ECMO) is inevitable external life support in case of cardiac and respiratory failure since the 1970s. Acute kidney injury (AKI) and the requirement of renal replacement..

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High Versus Low Blood Pressure Targets for Cardiac Surgery with Cardiopulmonary Bypass

Abstract This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: To assess the benefits and harms of a higher versus lower blood pressure target during..

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American Society of ExtraCorporeal Technology: Development of Standards and Guidelines for Pediatric and Congenital Perfusion Practice (2019)

Abstract The development of standards and guidelines by professional societies offers clinicians guidance toward providing evidence-based care. The ultimate goals of standards and guidelines are to standardize care and improve..

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Association Between Intraoperative Hyperoxia and Acute Kidney Injury After Cardiac Surgery: A Retrospective Observational Study

Abstract Objective Optimal oxygen management during cardiac surgery has not been established, and studies on the effects of perioperative hyperoxia on postoperative acute kidney injury (AKI) are scarce. The association..

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Conventional Ultrafiltration During Elective Cardiac Surgery and Postoperative Acute Kidney Injury

Abstract Objective Conventional ultrafiltration (CUF) during cardiopulmonary bypass (CPB) serves to hemoconcentrate blood volume to avoid allogeneic blood transfusions. Previous studies have determined CUF volumes as a continuous variable are..

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Goal-Directed Perfusion to Reduce Acute Kidney Injury after Paediatric Cardiac Surgery (GDP-Akip): Study Protocol for A Prospective Randomised Controlled Trial

Abstract Introduction Cardiac surgery-associated acute kidney injury (CS-AKI) occurs in up to 40%~60% of paediatric patients and increases postoperative morbidity and mortality. A goal-directed perfusion (GDP) strategy aimed at maintaining..

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