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Myocardial Protection in Adult Cardiac Surgery With del Nido Versus Blood Cardioplegia: A Systematic Review and Meta-Analysis

Abstract Background  in adult cardiac surgery is commonly achieved with either multidose blood  or single-dose del Nido crystalloid cardioplegia. Aim The aim of this systematic review and meta-analysis was to compare..

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Identification of risk factors for renal failure after cardiac surgery by RFILE classification

Abstract Objective: Acute kidney injury (AKI) is a major complication after cardiovascular surgery. The unclear etiology of this highly complex event challenges definition, diagnosis and prediction of AKI, and hence..

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Long-Term Cognitive Outcomes and Sleep in Adults After Extracorporeal Life Support

Abstract Objectives: To assess differences in cognitive outcomes and sleep in adult survivors of critical illness, managed with venovenous extracorporeal membrane oxygenation as compared to conventional mechanical ventilation only. Design:..

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Antecedent ACE-inhibition, inflammatory response, and cardiac surgery associated acute kidney injury

Abstract Cardiopulmonary bypass (CPB) may trigger organs damage, including kidney injury, due to a massive cytokine release. In this observational, prospective study, we analyzed the possible impact of chronic treatment..

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Is there a renoprotective value to leukodepletion during heart valve surgery? A randomized controlled trial (ROLO)

Abstract Background Acute Kidney Injury (AKI) adversely affects outcomes after cardiac surgery. A major mediator of AKI is the activation of leukocytes through exposure to the cardiopulmonary bypass circuit. We..

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Basics of extra corporeal membrane oxygenation: a pediatric intensivist’s perspective

Abstract Extra Corporeal membrane oxygenation (ECMO) is one of the most advanced forms of life support therapy in the Intensive Care Unit. It relies on the principle where an external..

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Prognostic Utility of KDIGO Urine Output Criteria After Cardiac Surgery

Abstract Objectives Kidney Disease: Improving Global Outcomes (KDIGO) guidelines include assessment of creatinine and urine output to identify acute kidney injury (AKI). Whether urine output is an accurate indicator of..

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Predicting acute kidney injury following nonemergent cardiac surgery: A preoperative scorecard

Abstract Objective To determine the predictors of postoperative acute kidney injury (AKI) following nonemergent cardiac surgery among patients with variable preoperative estimated glomerular filtration rate (eGFR) levels. Methods A retrospective..

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Allocating scarce intensive care resources during the COVID-19 pandemic: practical challenges to theoretical frameworks

Summary The COVID-19 pandemic strained health-care systems throughout the world. For some, available medical resources could not meet the increased demand and rationing was ultimately required. Hospitals and governments often..

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Hydroxyethyl starch and acute kidney injury in high-risk patients undergoing cardiac surgery: A prospective multicenter study

Abstract Background  (HES) solutions increase the risk of  (AKI) in critically ill patients admitted to intensive care unit (ICU) for medical indications. We conducted a cohort study to evaluate the renal..

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Management of Neonates With Tetralogy of Fallot

  Study Questions: What are the differences in outcomes between a strategy of staged repair (SR) (initial palliation [IP] and subsequent complete repair [CR]) as compared with primary repair (PR)..

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Feasibility of Healthcare Providers’ Autonomic Activation Recognition in Real-Life Cardiac Surgery Using Noninvasive Sensors

Abstract Cardiac surgery is one of the most complex specialties in medicine, akin to a complex sociotechnical system. Patient outcomes are vulnerable to surgical flow disruptions (SFDs), a source of..

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Cardiopulmonary bypass preparation is mandatory in cardiac exploration for blunt cardiac injury patients

Abstract Treating cardiac injuries following blunt trauma to the chest requires thorough examination, accurate diagnosis, and therapeutic plan. We present two cases; pulmonary vein rupture and left atrial appendage laceration,..

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The impact of minimal invasive extracorporeal circulation on postoperative kidney function

Abstract Introduction: Acute kidney injury following cardiac surgery is a frequent complication associated with increased mortality and morbidity. Minimal invasive extracorporeal circulation is suggested to preserve postoperative renal function. The..

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Unconscious (Implicit) Bias

Abstract Recognition, acknowledgment, and acceptance of biases in a nonjudgmental manner is key to advancing knowledge and avoiding biased behaviors. Unconscious biases do not mean people are bad, and they..

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Cardiac Biomarkers for Risk Stratification of Acute Kidney Injury After Pediatric Cardiac Surgery

Abstract Background Children undergoing a cardiac surgical procedure are at increased risk for acute kidney injury (AKI). Novel biomarkers are needed to improve risk stratification of AKI after cardiac surgery...

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Intraoperative crystalloid utilization variability and association with postoperative outcomes: A post hoc analysis of two multicenter prospective cohort studies

Abstract Background The optimal regimen for intravenous administration of intraoperative fluids remains unclear. Our goal was to analyze intraoperative crystalloid volume administration practices and their association with postoperative outcomes. Methods..

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Lab-created Heart Valves Can Grow With the Patient

  March 18, 2020 — A groundbreaking new study led by University of Minnesota Twin Cities researchers from both the College of Science and Engineering and the Medical School shows..

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Perioperative hemoglobin area under the curve is an independent predictor of renal failure after cardiac surgery. Results from a Spanish…

Abstract Perioperative anemia is an important risk factor for cardiac surgery-associated acute kidney injury (CSA-AKI). Nonetheless, the severity of the anemia and the time in the perioperative period in which..

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Preventing Publication of Falsified and Fabricated Data: Roles of Scientists, Editors, Reviewers, and Readers

Abstract In science, a research paper is often the final result of a process of hard work, perseverance, skills, and good ideas. Accurate communication of new research findings in the..

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Clinical Outcomes of Remote Ischemic Preconditioning Prior to Cardiac Surgery: A Meta‐Analysis of Randomized Controlled Trials

Abstract Background Multiple randomized controlled trials of remote ischemic preconditioning (RIPC) prior to cardiac surgery have failed to demonstrate clinical benefit. The aim of this updated meta‐analysis was to evaluate..

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Remifentanil prevents increases of blood glucose and lactate levels during cardiopulmonary bypass in pediatric cardiac surgery

Abstract Introduction:  Cardiopulmonary bypass (CPB) can cause stress response that increases levels of cytokine and catecholamine in plasma, resulting in hyperglycemia. In adults, it has been demonstrated that remifentanil infusion..

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ECMO in cardiac arrest and cardiogenic shock

Abstract Cardiogenic shock is an acute emergency, which is classically managed by medical support with inotropes or vasopressors and frequently requires invasive ventilation. However, both catecholamines and ventilation are associated..

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Association Between the Neutrophil/Lymphocyte Ratio and Acute Kidney Injury After Cardiovascular Surgery

Abstract A high neutrophil-lymphocyte ratio (N/L ratio) was associated with the development of acute kidney injury (AKI) in patients with severe sepsis. We sought to investigate the association between the..

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Is low serum albumin associated with postoperative complications in patients undergoing cardiac surgery?

Abstract A best evidence topic was written according to a structured protocol. The clinical question investigated was: is low serum albumin associated with postoperative complications in patients undergoing cardiac surgery?..

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Relationship between a perioperative intravenous fluid administration strategy and acute kidney injury following off-pump coronary artery bypass surgery: an observational…

Abstract Introduction Saline-based and hydroxyethyl starch solutions are associated with increased risk of renal dysfunction. In the present study, we tested the hypothesis that balanced solutions and a limited volume..

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Sodium Bicarbonate and Renal Function after Cardiac Surgery: A Prospectively Planned Individual Patient Meta-analysis

Abstract Background: The effect of urinary alkalinization in cardiac surgery patients at risk of acute kidney injury (AKI) is controversial and trial findings conflicting. Accordingly, the authors performed a prospectively..

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Venous Cannulation for Cardiopulmonary Bypass in the Case of Anomaly of the Inferior Vena Cava

Abstract  of the  and its tributaries are quite uncommon; however, since the development of , they have been described more frequently. Most of them are usually asymptomatic, although they can have clinical..

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The use of preoperative aspirin in cardiac surgery: A systematic review and meta‐analysis

Abstract Background Despite the fact that aspirin is of benefit to patients following coronary artery bypass grafting (CABG), continuation or administration of preoperative aspirin before CABG or any cardiac surgical..

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Effect of Levosimendan on Low Cardiac Output Syndrome in Patients With Low Ejection Fraction Undergoing Coronary Artery Bypass Grafting With…

Abstract Importance   Low cardiac output syndrome after cardiac surgery is associated with high morbidity and mortality in patients with impaired left ventricular function. Objective   To assess the ability of preoperative..

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