Abstract Background in adult cardiac surgery is commonly achieved with either multidose blood or single-dose del Nido crystalloid cardioplegia. Aim The aim of this systematic review and meta-analysis was to compare..
Read MoreAbstract Objective: Acute kidney injury (AKI) is a major complication after cardiovascular surgery. The unclear etiology of this highly complex event challenges definition, diagnosis and prediction of AKI, and hence..
Read MoreAbstract Objectives: To assess differences in cognitive outcomes and sleep in adult survivors of critical illness, managed with venovenous extracorporeal membrane oxygenation as compared to conventional mechanical ventilation only. Design:..
Read MoreAntecedent ACE-inhibition, inflammatory response, and cardiac surgery associated acute kidney injury
Abstract Cardiopulmonary bypass (CPB) may trigger organs damage, including kidney injury, due to a massive cytokine release. In this observational, prospective study, we analyzed the possible impact of chronic treatment..
Read MoreAbstract Background Acute Kidney Injury (AKI) adversely affects outcomes after cardiac surgery. A major mediator of AKI is the activation of leukocytes through exposure to the cardiopulmonary bypass circuit. We..
Read MoreAbstract Extra Corporeal membrane oxygenation (ECMO) is one of the most advanced forms of life support therapy in the Intensive Care Unit. It relies on the principle where an external..
Read MoreAbstract Objectives Kidney Disease: Improving Global Outcomes (KDIGO) guidelines include assessment of creatinine and urine output to identify acute kidney injury (AKI). Whether urine output is an accurate indicator of..
Read MoreAbstract Objective To determine the predictors of postoperative acute kidney injury (AKI) following nonemergent cardiac surgery among patients with variable preoperative estimated glomerular filtration rate (eGFR) levels. Methods A retrospective..
Read MoreSummary The COVID-19 pandemic strained health-care systems throughout the world. For some, available medical resources could not meet the increased demand and rationing was ultimately required. Hospitals and governments often..
Read MoreAbstract Background (HES) solutions increase the risk of (AKI) in critically ill patients admitted to intensive care unit (ICU) for medical indications. We conducted a cohort study to evaluate the renal..
Read MoreStudy Questions: What are the differences in outcomes between a strategy of staged repair (SR) (initial palliation [IP] and subsequent complete repair [CR]) as compared with primary repair (PR)..
Read MoreAbstract Cardiac surgery is one of the most complex specialties in medicine, akin to a complex sociotechnical system. Patient outcomes are vulnerable to surgical flow disruptions (SFDs), a source of..
Read MoreAbstract Treating cardiac injuries following blunt trauma to the chest requires thorough examination, accurate diagnosis, and therapeutic plan. We present two cases; pulmonary vein rupture and left atrial appendage laceration,..
Read MoreAbstract Introduction: Acute kidney injury following cardiac surgery is a frequent complication associated with increased mortality and morbidity. Minimal invasive extracorporeal circulation is suggested to preserve postoperative renal function. The..
Read MoreAbstract Recognition, acknowledgment, and acceptance of biases in a nonjudgmental manner is key to advancing knowledge and avoiding biased behaviors. Unconscious biases do not mean people are bad, and they..
Read MoreAbstract Background Children undergoing a cardiac surgical procedure are at increased risk for acute kidney injury (AKI). Novel biomarkers are needed to improve risk stratification of AKI after cardiac surgery...
Read MoreAbstract Background The optimal regimen for intravenous administration of intraoperative fluids remains unclear. Our goal was to analyze intraoperative crystalloid volume administration practices and their association with postoperative outcomes. Methods..
Read MoreMarch 18, 2020 — A groundbreaking new study led by University of Minnesota Twin Cities researchers from both the College of Science and Engineering and the Medical School shows..
Read MoreAbstract Perioperative anemia is an important risk factor for cardiac surgery-associated acute kidney injury (CSA-AKI). Nonetheless, the severity of the anemia and the time in the perioperative period in which..
Read MoreAbstract In science, a research paper is often the final result of a process of hard work, perseverance, skills, and good ideas. Accurate communication of new research findings in the..
Read MoreAbstract Background Multiple randomized controlled trials of remote ischemic preconditioning (RIPC) prior to cardiac surgery have failed to demonstrate clinical benefit. The aim of this updated meta‐analysis was to evaluate..
Read MoreAbstract Introduction: Cardiopulmonary bypass (CPB) can cause stress response that increases levels of cytokine and catecholamine in plasma, resulting in hyperglycemia. In adults, it has been demonstrated that remifentanil infusion..
Read MoreAbstract Cardiogenic shock is an acute emergency, which is classically managed by medical support with inotropes or vasopressors and frequently requires invasive ventilation. However, both catecholamines and ventilation are associated..
Read MoreAbstract A high neutrophil-lymphocyte ratio (N/L ratio) was associated with the development of acute kidney injury (AKI) in patients with severe sepsis. We sought to investigate the association between the..
Read MoreAbstract A best evidence topic was written according to a structured protocol. The clinical question investigated was: is low serum albumin associated with postoperative complications in patients undergoing cardiac surgery?..
Read MoreAbstract Introduction Saline-based and hydroxyethyl starch solutions are associated with increased risk of renal dysfunction. In the present study, we tested the hypothesis that balanced solutions and a limited volume..
Read MoreAbstract Background: The effect of urinary alkalinization in cardiac surgery patients at risk of acute kidney injury (AKI) is controversial and trial findings conflicting. Accordingly, the authors performed a prospectively..
Read MoreAbstract of the and its tributaries are quite uncommon; however, since the development of , they have been described more frequently. Most of them are usually asymptomatic, although they can have clinical..
Read MoreAbstract Background Despite the fact that aspirin is of benefit to patients following coronary artery bypass grafting (CABG), continuation or administration of preoperative aspirin before CABG or any cardiac surgical..
Read MoreAbstract Importance Low cardiac output syndrome after cardiac surgery is associated with high morbidity and mortality in patients with impaired left ventricular function. Objective To assess the ability of preoperative..
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