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Association Between Preoperative Statin Exposure and Acute Kidney Injury in Adult Patients Undergoing Cardiac Surgery

Abstract Objectives The existing literature has shown conflicting results regarding the association between preoperative statin exposure and the risk of postoperative cardiac surgery–associated  (CSA-AKI). Design A single-center retrospective observational study. Setting..

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The Case for the Anesthesiologist-Informaticist

Abstract Health care has been transformed by computerization, and the use of electronic health record systems has become widespread. Anesthesia information management systems are commonly used in the operating room..

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Evaluation of the effects of three designs of oxygenators with integrated filters on clinical and haematological outcomes at an Australasian…

Abstract Introduction: Cardiopulmonary bypass (CPB) machines have oxygenators with integrated filters and unique biocompatible coatings to combat systemic inflammatory response syndrome (SIRS) and mitigate coagulopathy. Contemporary oxygenators have undergone comparative..

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Risk Factors for Acute Kidney Injury Following Cardiac Surgery and Performance of Leicester Score in a Spanish Cohort

Abstract The incidence of acute kidney injury following cardiac surgery (CSA-AKI) is up to 30%, and it places patients at an increased risk of death. The Leicester score (LS) is..

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Veno-Venous Extracorporeal Rewarming Using Dual-Lumen Cannula in Accidental Hypothermia

Abstract Accidental hypothermia with a core temperature below 28°C is associated with an increased risk of hemodynamic instability. It is difficult to predict which patients will survive with a favorable..

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Using machine learning to predict perfusionists’ critical decision-making during cardiac surgery

Abstract The cardiac surgery operating room is a high-risk and complex environment in which multiple experts work as a team to provide safe and excellent care to patients. During the..

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Beneficial effect of ECMO on survival in patients affected by ARDS due to COVID-19.

Abstract Where is the imperceptible difference? With great interest, we read the recent article by Whebell and colleagues [1] and were appealed by the beneficial effect of extracorporeal membrane oxygenation..

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Effect of intrarenal renin-angiotensin-aldosterone system on renal function in patients after cardiac surgery

Abstract The aim of the study was to investigate the influence of intrarenal RAS on the decrease of renal function in patients undergoing cardiac surgery with cardiopulmonary bypass. This observational..

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A Global Definition of Patient Blood Management

Abstract While patient blood management (PBM) initiatives are increasingly adopted across the globe as part of standard of care, there is need for a clear and widely accepted definition of..

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Blood pressure variability during pediatric cardiac surgery is associated with acute kidney injury

Abstract Background Blood pressure variability (BPV), defined as the degree of variation between discrete blood pressure readings, is associated with poor outcomes in acute care settings. Acute kidney injury (AKI)..

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Goal-directed perfusion for reducing acute kidney injury in cardiac surgery: A systematic review and meta-analysis

Abstract Background Acute kidney injury (AKI) is a common complication following cardiopulmonary bypass (CPB) which can affect morbidity and mortality. Goal-directed perfusion (GDP) intended to avoid the nadir oxygen delivery..

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Magnetic levitation pumps for cell-free hemoglobin prevention during VV ECMO

Abstract Increased plasma concentrations of circulating cell-free hemoglobin (CFH) are supposed to contribute to the multifactorial etiology of acute kidney injury (AKI). In their recent article: “The role of cell-free..

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Prediction of the severity of acute kidney injury after on-pump cardiac surgery

Abstract Study objective On-pump cardiac surgery is associated with a high risk of acute kidney injury (AKI), which can substantially affect risk of mortality and morbidity depending on its severity...

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Is postoperative cognitive decline after cardiac surgery associated with plasma beta amyloid 1–42 levels?

Abstract Background Postoperative cognitive decline following cardiac surgery is one of the frequently reported complications affecting postoperative outcome, characterized by impairment of memory or concentration. The aetiology is considered multifactorial..

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AI in health and medicine

Abstract Artificial intelligence (AI) is poised to broadly reshape medicine, potentially improving the experiences of both clinicians and patients. We discuss key findings from a 2-year weekly effort to track..

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Association of urine output during cardiopulmonary bypass and postoperative acute kidney injury in patients undergoing coronary artery bypass graft

Abstract Introduction Acute kidney injury (AKI) is a common complication in patients undergoing coronary artery bypass graft (CABG) surgery and is associated with significant morbidity and mortality. We investigated the..

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Blood Protection Method: Retrograde Autologous Prime

Blood Protection Method: Retrograde Autologous Prime   In order to carry out open heart surgery, the functions of the heart and lungs must be stopped and the blood inside the..

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Modeling acid-base balance for in-series extracorporeal carbon dioxide removal and continuous venovenous hemofiltration devices

Abstract Patients with acute respiratory distress syndrome and acute kidney injury (AKI) treated by kidney replacement therapy may also require treatment with extracorporeal carbon dioxide removal (ECCO2R) devices to permit..

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To RAP or Not to RAP: A Retrospective Comparison of the Effects of Retrograde Autologous Priming

Abstract Retrograde autologous priming (RAP) is a process used to reduce hemodilution associated with the initiation of cardiopulmonary bypass (CPB). Previous studies have reported potential benefits to RAP; however, many..

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Tracheostomy Practices and Outcomes in Children During Respiratory Extracorporeal Membrane Oxygenation

Abstract Objectives:  Children receiving prolonged extracorporeal membrane oxygenation (ECMO) support may benefit from tracheostomy during ECMO by facilitating rehabilitation; however, the procedure carries risks, especially hemorrhagic complications. Knowledge of tracheostomy practices and outcomes of..

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Pulsatil and NonPulsatil Current in Cardiopulmonary Bypass

Abstract Heart disease is among the most important health problems in our country and in the world. Heart diseases are widely repaired in adults, children and newborns with open heart..

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Making transfusion medicine a journey from good to great by using quality indicators and bringing in continuous quality improvement

Abstract From its foundational years, transfusion medicine (TM) has been associated with errors and their reporting. Patient safety and quality were brought to the forefront of health care through the..

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Vacuum-assisted venous drainage, angel or demon: PRO?

Abstract Vacuum-assisted venous drainage (VAVD) was proposed to optimize venous drainage during bypass through femoral venous cannulation. It is currently used in both adult and pediatric surgery when siphon gravity..

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Equitable Open Access Publishing: Changing the Financial Power Dynamics in Academia

Abstract Open access (OA) publishing is increasing, allowing articles to be read by anyone, anywhere. The publishing costs for these articles (article processing charges, APCs) are typically paid by the..

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Impact of partial pressure of oxygen trajectories on the incidence of acute kidney injury in patients undergoing cardiopulmonary bypass

Abstract Background To investigate the impact of the dynamic oxygenation status on the incidence of acute kidney injury (AKI) in patients undergoing cardiopulmonary bypass. Methods This retrospective study was performed..

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Liberation From Venoarterial Extracorporeal Membrane Oxygenation: A Review

Abstract Venoarterial extracorporeal membrane oxygenation may be used for circulatory support in cardiogenic shock as a bridge to recovery, a bridge to a ventricular assist device (VAD), or a bridge..

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PHYSIOLOGIC EFFECTS OF CONTINUOUS-FLOW LEFT VENTRICULAR ASSIST DEVICES

Abstract Background Within the past ten years, continuous-flow Left Ventricular Assist Devices (LVADS) have replaced pulsatile-flow LVADs as the standard of care for both destination therapy and bridging patients to..

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Gelatin and the risk of acute kidney injury after cardiac surgery

Abstract Background Gelatin has been used as a plasma volume expander because of its ability to preserve intravascular volume more effectively than crystalloids. However, gelatin may have detrimental effects on..

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The Role of Race on Acute Kidney Injury Following Cardiac Surgery

Abstract Background Acute kidney injury (AKI) frequently complicates cardiac surgery and is more common among Black patients. We evaluated determinants of race-based differences in AKI rates. Methods Serum creatinine-based criteria..

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Ultrafiltration and cardiopulmonary bypass associated acute kidney injury: A systematic review and meta-analysis

Abstract Background Cardiopulmonary bypass is known to raise the risk of acute kidney injury (AKI). Previous studies have identified numerous risk factors of cardiopulmonary bypass including the possible impact of..

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