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Association of urine output during cardiopulmonary bypass and postoperative acute kidney injury in patients undergoing coronary artery bypass graft

Abstract Introduction Acute kidney injury (AKI) is a common complication in patients undergoing coronary artery bypass graft (CABG) surgery and is associated with significant morbidity and mortality. We investigated the..

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Blood Protection Method: Retrograde Autologous Prime

Blood Protection Method: Retrograde Autologous Prime   In order to carry out open heart surgery, the functions of the heart and lungs must be stopped and the blood inside the..

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Modeling acid-base balance for in-series extracorporeal carbon dioxide removal and continuous venovenous hemofiltration devices

Abstract Patients with acute respiratory distress syndrome and acute kidney injury (AKI) treated by kidney replacement therapy may also require treatment with extracorporeal carbon dioxide removal (ECCO2R) devices to permit..

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To RAP or Not to RAP: A Retrospective Comparison of the Effects of Retrograde Autologous Priming

Abstract Retrograde autologous priming (RAP) is a process used to reduce hemodilution associated with the initiation of cardiopulmonary bypass (CPB). Previous studies have reported potential benefits to RAP; however, many..

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Tracheostomy Practices and Outcomes in Children During Respiratory Extracorporeal Membrane Oxygenation

Abstract Objectives:  Children receiving prolonged extracorporeal membrane oxygenation (ECMO) support may benefit from tracheostomy during ECMO by facilitating rehabilitation; however, the procedure carries risks, especially hemorrhagic complications. Knowledge of tracheostomy practices and outcomes of..

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Pulsatil and NonPulsatil Current in Cardiopulmonary Bypass

Abstract Heart disease is among the most important health problems in our country and in the world. Heart diseases are widely repaired in adults, children and newborns with open heart..

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Making transfusion medicine a journey from good to great by using quality indicators and bringing in continuous quality improvement

Abstract From its foundational years, transfusion medicine (TM) has been associated with errors and their reporting. Patient safety and quality were brought to the forefront of health care through the..

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Vacuum-assisted venous drainage, angel or demon: PRO?

Abstract Vacuum-assisted venous drainage (VAVD) was proposed to optimize venous drainage during bypass through femoral venous cannulation. It is currently used in both adult and pediatric surgery when siphon gravity..

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Equitable Open Access Publishing: Changing the Financial Power Dynamics in Academia

Abstract Open access (OA) publishing is increasing, allowing articles to be read by anyone, anywhere. The publishing costs for these articles (article processing charges, APCs) are typically paid by the..

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Impact of partial pressure of oxygen trajectories on the incidence of acute kidney injury in patients undergoing cardiopulmonary bypass

Abstract Background To investigate the impact of the dynamic oxygenation status on the incidence of acute kidney injury (AKI) in patients undergoing cardiopulmonary bypass. Methods This retrospective study was performed..

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Liberation From Venoarterial Extracorporeal Membrane Oxygenation: A Review

Abstract Venoarterial extracorporeal membrane oxygenation may be used for circulatory support in cardiogenic shock as a bridge to recovery, a bridge to a ventricular assist device (VAD), or a bridge..

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PHYSIOLOGIC EFFECTS OF CONTINUOUS-FLOW LEFT VENTRICULAR ASSIST DEVICES

Abstract Background Within the past ten years, continuous-flow Left Ventricular Assist Devices (LVADS) have replaced pulsatile-flow LVADs as the standard of care for both destination therapy and bridging patients to..

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Gelatin and the risk of acute kidney injury after cardiac surgery

Abstract Background Gelatin has been used as a plasma volume expander because of its ability to preserve intravascular volume more effectively than crystalloids. However, gelatin may have detrimental effects on..

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The Role of Race on Acute Kidney Injury Following Cardiac Surgery

Abstract Background Acute kidney injury (AKI) frequently complicates cardiac surgery and is more common among Black patients. We evaluated determinants of race-based differences in AKI rates. Methods Serum creatinine-based criteria..

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Ultrafiltration and cardiopulmonary bypass associated acute kidney injury: A systematic review and meta-analysis

Abstract Background Cardiopulmonary bypass is known to raise the risk of acute kidney injury (AKI). Previous studies have identified numerous risk factors of cardiopulmonary bypass including the possible impact of..

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Impact of partial pressure of oxygen trajectories on the incidence of acute kidney injury in patients undergoing cardiopulmonary bypass

Abstract Background To investigate the impact of the dynamic oxygenation status on the incidence of acute kidney injury (AKI) in patients undergoing cardiopulmonary bypass. Methods This retrospective study was performed..

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Extracorporeal membrane oxygenation in children receiving haematopoietic cell transplantation and immune effector cell therapy: an international and multidisciplinary consensus statement

Abstract Use of extracorporeal membrane oxygenation (ECMO) in children receiving haematopoietic cell transplantation (HCT) and immune effector cell therapy is controversial and evidence-based guidelines have not been established. Remarkable advancements..

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Prediction of acute kidney injury after cardiac surgery from preoperative N-terminal pro-B-type natriuretic peptide

Abstract Background  (AKI) is common after cardiac surgery and is difficult to predict. N-terminal pro-B-type natriuretic peptide (NT-proBNP) is highly predictive for perioperative cardiovascular complications and may also predict renal..

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How to set up and run a surgical research laboratory

Abstract Surgical research has shifted from the laboratory focus of the mid to late 20th century to a more mixed economy of data science, collaborative and qualitative research, with a..

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The importance of evidence-based surgery, surgical protocols and research methodologies

Abstract The objective of clinical research is to establish ethically and methodologically sound evidence that can aid clinical decision-making, inform ongoing research and add to the existing body of knowledge...

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Under-recognition of Acute Kidney Injury after Cardiac Surgery in the ICU Impedes Early Detection and Prevention

Abstract Background: Acute kidney injury (AKI) is associated with high morbidity and mortality; therefore, prevention is important. The aim of this study was to systematically assess AKI incidence after cardiac surgery..

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Early mobilisation algorithm for the critical patient. Expert recommendations

Abstract Introduction  (ICU)-acquired weakness is developed by 40%–46% of patients admitted to ICU. Different studies have shown that Early Mobilisation (EM) is safe, feasible, cost-effective and improves patient outcomes in..

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Postcardiotomy Extracorporeal Membrane Oxygenation: Narrative Review Navigating the Ethical Issues

Abstract Postcardiotomy shock (PCS) is an uncommon and life-threatening .  (ECMO) is the first line of mechanical  for treating PCS when medical therapies are insufficient. Reaching a “therapeutic ceiling” or a “bridge to..

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Factors for Acute Kidney Injury Following Total Arch Replacement and Association with Temperature Management During Cardiopulmonary Bypass: A Single-center Retrospective…

Abstract Many patients develop acute kidney injury (AKI) after vascular surgery. In this retrospective observational study, we investigated the risk factors for AKI defined using the Kidney Disease Improving Global..

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Prediction Scores for Any-Stage and Stage-3 Acute Kidney Injury After Adult Cardiac Surgery in a Chinese Population

Abstract Objectives This study was performed to internally derive and then validate risk score systems using preoperative and intraoperative variables to predict the occurrence of any-stage (stage 1, 2, 3)..

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The multivariable prognostic models for severe complications after heart valve surgery

Abstract Background To provide multivariable prognostic models for severe complications prediction after heart valve surgery, including low cardiac output syndrome (LCOS), acute kidney injury requiring hemodialysis (AKI-rH) and multiple organ..

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Renal function and inflammatory response in neonates undergoing cardiac surgery with or without antegrade cerebral perfusion—a post hoc analysis

Abstract Background: Cardiopulmonary bypass (CPB) may lead to tissue hypoxia, inflammatory response, and risk for acute kidney injury (AKI). We evaluated the prevalence of AKI and inflammatory response in neonates undergoing..

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Low Mean Arterial Pressure During Cardiopulmonary Bypass and the Risk of Acute Kidney Injury: A Propensity Score Matched Observational Study

Abstract Introduction Low mean arterial pressure (MAP) periods occur frequently during cardiopulmonary bypass (CPB), and their management remains controversial. Our aim was to correlate MAP during CPB with the occurrence..

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Strategies to Prevent Acute Kidney Injury after Pediatric Cardiac Surgery

Abstract Background and objectives AKI is a common complication after pediatric cardiac surgery and has been associated with higher morbidity and mortality. We aimed to compare the efficacy of available pharmacologic..

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