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Escalating and De-escalating Temporary Mechanical Circulatory Support in Cardiogenic Shock: A Scientific Statement From the American Heart Association

Abstract The use of temporary mechanical circulatory support in cardiogenic shock has increased dramatically despite a lack of randomized controlled trials or evidence guiding clinical decision-making. Recommendations from professional societies..

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Society of Cardiovascular Anesthesiologists Clinical Practice Update for Management of Acute Kidney Injury Associated With Cardiac Surgery

Abstract Cardiac surgery-associated acute kidney injury (CS-AKI) is common and is associated with increased risk for postoperative morbidity and mortality. Our recent survey of the Society of Cardiovascular Anesthesiologists (SCA)..

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Cardiac Dysfunction Biomarkers are Associated with Potential for Successful Separation from Extracorporeal Membrane Oxygenation in Children

Abstract Biomarkers of cardiac dysfunction may aid in decision making about organ recovery and optimal timing of separation from extracorporeal membrane oxygenation (ECMO). We conducted a prospective observational study of..

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Cardiac Surgery Associated AKI Prevention Strategies and Medical Treatment for CSA-AKI

Abstract Acute kidney injury (AKI) is common after cardiac surgery. To date, there are no specific pharmacological therapies. In this review, we summarise the existing evidence for prevention and management..

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Human albumin and 6% hydroxyethyl starches (130/0.4) in cardiac surgery: a meta-analysis revisited

Abstract Background A meta-analysis of randomized controlled trials was recently published in BMC Surgery that compared the use of human albumin with 6% hydroxyethyl starches 130/0.4 for cardiopulmonary bypass prime..

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Outcome of post‑traumatic acute respiratory distress syndrome in young patients requiring extracorporeal membrane oxygenation (ECMO)

Abstract We aimed to evaluate the outcomes of post‑traumatic acute respiratory distress syndrome (ARDS)in young patients with and without Extracorporeal membrane oxygenation (ECMO) support. A retrospective analysis was conducted for..

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Risk score for arch reconstruction under circulatory arrest with hypothermia: The ARCH score

Abstract Objective Currently, there is no risk scores built to predict risk in thoracic aortic surgery. This study aims to develop and internally validate a risk prediction score for patients..

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Hemorrhagic complications in Veno-Venous Extracorporeal life Support—Development and internal validation of multivariable prediction model in adult patients

Abstract Background During extracorporeal life support (ECLS), bleeding is one of the most frequent complications, associated with high morbidity and increased mortality, despite continuous improvements in devices and patient care...

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Cardiac surgery on patients with COVID-19: a systematic review and meta-analysis

Abstract Introduction The COVID-19 pandemic has had a significant impact on global surgery. In particular, deleterious effects of SARS-CoV-2 infection on the heart and cardiovascular system have been described. To..

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Oxygen Delivery in Pediatric Cardiac Surgery and its Association with Acute Kidney Injury using Machine Learning

Abstract Objective Acute kidney injury (AKI) following pediatric cardiac surgery with cardiopulmonary bypass is a frequently reported complication. This study aims to determine the critical oxygen delivery (DO2i) threshold associated..

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Interprofessional model on speaking up behaviour in healthcare professionals: a qualitative study

Abstract Objectives Despite training and the recognition that speaking up can mitigate harm to patients and save lives, healthcare professionals do not consistently speak up when they have patient safety concerns...

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The problem with making Safety-II work in healthcare

Abstract Patient safety is typically assessed by the frequency of adverse events or incidents, which means we seek to determine safety by its absence rather than its presence. The Safety-II perspective..

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Gelatin and the risk of acute kidney injury after cardiac surgery

Abstract Background Gelatin has been used as a plasma volume expander because of its ability to preserve intravascular volume more effectively than crystalloids. However, gelatin may have detrimental effects on..

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Continuous renal replacement therapy in patients treated with extracorporeal membrane oxygenation

Abstract Extracorporeal membrane oxygenation (ECMO) is a life-saving therapy utilized for patients with severe life-threatening cardiorespiratory failure. Patients treated with ECMO are among the most severely ill encountered in critical..

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Extracorporeal interval support for organ retrieval delivery regional experience with sharing equipe, equipment & expertise to increase conventionally defined as…

Abstract Donation after circulatory death (DCD) programs are expanding in Europe, in the attempt to expand donors pool. Even in controlled DCD donors, however, a protracted warm ischemia time occurring..

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Association Between Preoperative Statin Exposure and Acute Kidney Injury in Adult Patients Undergoing Cardiac Surgery

Abstract Objectives The existing literature has shown conflicting results regarding the association between preoperative statin exposure and the risk of postoperative cardiac surgery–associated  (CSA-AKI). Design A single-center retrospective observational study. Setting..

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The Case for the Anesthesiologist-Informaticist

Abstract Health care has been transformed by computerization, and the use of electronic health record systems has become widespread. Anesthesia information management systems are commonly used in the operating room..

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Evaluation of the effects of three designs of oxygenators with integrated filters on clinical and haematological outcomes at an Australasian…

Abstract Introduction: Cardiopulmonary bypass (CPB) machines have oxygenators with integrated filters and unique biocompatible coatings to combat systemic inflammatory response syndrome (SIRS) and mitigate coagulopathy. Contemporary oxygenators have undergone comparative..

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Risk Factors for Acute Kidney Injury Following Cardiac Surgery and Performance of Leicester Score in a Spanish Cohort

Abstract The incidence of acute kidney injury following cardiac surgery (CSA-AKI) is up to 30%, and it places patients at an increased risk of death. The Leicester score (LS) is..

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Veno-Venous Extracorporeal Rewarming Using Dual-Lumen Cannula in Accidental Hypothermia

Abstract Accidental hypothermia with a core temperature below 28°C is associated with an increased risk of hemodynamic instability. It is difficult to predict which patients will survive with a favorable..

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Using machine learning to predict perfusionists’ critical decision-making during cardiac surgery

Abstract The cardiac surgery operating room is a high-risk and complex environment in which multiple experts work as a team to provide safe and excellent care to patients. During the..

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Beneficial effect of ECMO on survival in patients affected by ARDS due to COVID-19.

Abstract Where is the imperceptible difference? With great interest, we read the recent article by Whebell and colleagues [1] and were appealed by the beneficial effect of extracorporeal membrane oxygenation..

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Effect of intrarenal renin-angiotensin-aldosterone system on renal function in patients after cardiac surgery

Abstract The aim of the study was to investigate the influence of intrarenal RAS on the decrease of renal function in patients undergoing cardiac surgery with cardiopulmonary bypass. This observational..

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A Global Definition of Patient Blood Management

Abstract While patient blood management (PBM) initiatives are increasingly adopted across the globe as part of standard of care, there is need for a clear and widely accepted definition of..

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Blood pressure variability during pediatric cardiac surgery is associated with acute kidney injury

Abstract Background Blood pressure variability (BPV), defined as the degree of variation between discrete blood pressure readings, is associated with poor outcomes in acute care settings. Acute kidney injury (AKI)..

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Goal-directed perfusion for reducing acute kidney injury in cardiac surgery: A systematic review and meta-analysis

Abstract Background Acute kidney injury (AKI) is a common complication following cardiopulmonary bypass (CPB) which can affect morbidity and mortality. Goal-directed perfusion (GDP) intended to avoid the nadir oxygen delivery..

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Magnetic levitation pumps for cell-free hemoglobin prevention during VV ECMO

Abstract Increased plasma concentrations of circulating cell-free hemoglobin (CFH) are supposed to contribute to the multifactorial etiology of acute kidney injury (AKI). In their recent article: “The role of cell-free..

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Prediction of the severity of acute kidney injury after on-pump cardiac surgery

Abstract Study objective On-pump cardiac surgery is associated with a high risk of acute kidney injury (AKI), which can substantially affect risk of mortality and morbidity depending on its severity...

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Is postoperative cognitive decline after cardiac surgery associated with plasma beta amyloid 1–42 levels?

Abstract Background Postoperative cognitive decline following cardiac surgery is one of the frequently reported complications affecting postoperative outcome, characterized by impairment of memory or concentration. The aetiology is considered multifactorial..

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AI in health and medicine

Abstract Artificial intelligence (AI) is poised to broadly reshape medicine, potentially improving the experiences of both clinicians and patients. We discuss key findings from a 2-year weekly effort to track..

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