Abstract BACKGROUND Increasing evidence from randomised controlled trials supports the implementation of a six-measure care bundle proposed by the Kidney Disease Improving Global Outcomes (KDIGO) guidelines in patients at high..
Read MoreAbstract Background Prolonged post-surgery intensive care unit (ICU) stay for congenital heart disease (CHD) has been explored in the pediatric population. However, there is limited data for adult CHD (ACHD),..
Read MoreAbstract Study Objective: To investigate whether large volume acute normovolemic (L-ANH), compared with moderate acute normovolemic (M-ANH), can reduce perioperative allogeneic with intermediate-high risk of transfusion during cardiac surgery with (CPB). Design: Prospective . Setting:..
Read MoreAbstract Our primary objective was to identify if fasciotomy was associated with increased mortality in patients who developed acute compartment syndrome (ACS) on extracorporeal cardiopulmonary resuscitation (ECPR). Additionally, we sought to identify any additional risk factors..
Read MoreAbstract OBJECTIVES: Near-infrared spectroscopy (NIRS) has been increasingly accepted as a noninvasive marker of regional tissue oxygenation despite concerns of imprecision and wide limits of agreement (LOA) with invasive oximetry. New generation absolute..
Read MoreAbstract Background: Physical therapy (PT) utilization in patients requiring mechanical circulatory support (MCS) and extracorporeal membrane oxygenation (ECMO) has been reported; however, little is known about intensive rehabilitation and associated..
Read MoreAbstract Acute kidney injury (AKI) is a frequent complication of cardiac surgery that contributes to postoperative morbidity and mortality. The timing of renal replacement therapy (RRT) remains unclear. The Artificial..
Read MoreAbstract Objectives The benefit of using gelatin solution in cardiac surgery is still controversial. Previous data suggested adverse interactions of gelatin infusion with (AKI) or . The purpose of this study was..
Read MoreAbstract Objective: The aim of this study was to describe decisions about the escalation and withdrawal of treatment for patients on extracorporeal membrane oxygenation (ECMO). Summary Background Data: Interventions premised..
Read MoreAbstract Background We aimed to compare the frequency of acute kidney injury (AKI) and its effects on mortality and morbidity with different classification systems in pediatric patients who had surgery..
Read MoreAbstract Background The purpose of this Neonatal and Pediatric Heart and Renal Outcomes Network study was to describe the and outcomes of cardiac surgery–associated (CS-AKI) after cardiac surgery without (non-CPB). Methods We performed..
Read MoreAbstract Background Despite recent data suggesting improved outcomes with bivalirudin vs heparin in pediatric Ventricular assist devices (VAD), higher costs remain a barrier. This study quantified trends in bivalirudin use..
Read MoreAbstract The pulse oximeter is a device that estimates a person’s oxygen saturation level, a measure of the oxygen concentration in their blood, by shining light through their tissue, typically..
Read MoreAbstract Objective To investigate if oxygen delivery index during (DO2I) was more strongly associated with (AKI), the higher the patient's preoperative pulse pressure (PP). Design Retrospective cohort of 1064 patients undergoing cardiac..
Read MoreAbstract Background The preferred configuration for bridging patients with respiratory failure while awaiting is venovenous (VV ECMO). However, the protective effect of VV ECMO on the lung, as well as the underlying..
Read MoreIntroduction The startling revelation that one fifth of health expenditure makes little contribution to good health outcomes is surely a call to action to tackle waste in the delivery of care...
Read MoreAbstract Veno-venous extracorporeal membrane oxygenation (V–V ECMO) has an established evidence base in acute respiratory distress syndrome (ARDS) and has seen exponential growth in its use over the past decades...
Read MoreAbstract Introduction Critical incident reporting systems (CIRS) are in use worldwide. They are designed to improve patient care by detecting and analyzing critical and adverse patient events and by taking..
Read MoreAbstract Objectives Medical care in low-income countries is often limited by inadequate resources, treatment facilities, and the necessary infrastructure for healthcare delivery. We hypothesized that the development of an independently..
Read MoreAbstract Acute kidney injury (AKI) is a common and serious complication of cardiac surgery and is associated with increased mortality and morbidity, accompanied by a substantial economic burden. The pathogenesis..
Read MoreAbstract Combined advances in haematopoietic cell transplantation (HCT) and intensive care management have improved the survival of patients with haematological malignancies admitted to the intensive care unit. In cases of..
Read MoreAbstract Veno-venous extracorporeal membrane oxygenation (V–V ECMO) has an established evidence base in acute respiratory distress syndrome (ARDS) and has seen exponential growth in its use over the past decades...
Read MoreAbstract High-volume extracorporeal membrane oxygenation (ECMO) centers generally have better outcomes than (new) low-volume ECMO centers, most likely achieved by a suitable exposure to ECMO cases. To achieve a higher..
Read MoreAbstract High-volume extracorporeal membrane oxygenation (ECMO) centers generally have better outcomes than (new) low-volume ECMO centers, most likely achieved by a suitable exposure to ECMO cases. To achieve a higher..
Read MoreAbstract Objective: Assessment of the results of the ProtekDuo cannula applied for dedicated right ventricular support with oxygenator in ARDS secondary to COVID-19. Methods: Systematic literature search in NHS library,..
Read MoreAbstract Cardiopulmonary bypass (CPB) is a complex biomechanical engineering undertaking and an essential component of cardiac surgery. However, similar to all complex bioengineering systems, CPB activities are prone to a..
Read MoreAbstract Acute kidney injury (AKI) is one of the most common major complications of cardiac surgery, and is associated with increased morbidity and mortality. Cardiac surgery-associated AKI has a complex,..
Read MoreAbstract Patients receiving extracorporeal membrane oxygenation (ECMO) inherit substantial disease-associated metabolic, endocrinologic, and immunologic modifications. Along with the technical components of ECMO, the aforementioned alterations may affect patients' needs and..
Read MoreAbstract Background Mechanical ventilation is a technique for supporting or substituting respiration. Fibrin deposition in the pulmonary microcirculation and alveolar sacs (hyaline membrane generation) is a major inflammatory route of..
Read MoreAbstract Introduction Cardiac surgery associated acute kidney injury (CSA-AKI) has a number of preoperative and intraoperative risk factors. Cardiopulmonary bypass (CPB) factors have not yet been elucidated in a single..
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