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Machine learning using institution-specific multi-modal electronic health records improves mortality risk prediction for cardiac surgery patients

Abstract Background The Society of Thoracic Surgeons risk scores are widely used to assess risk of morbidity and mortality in specific cardiac surgeries but may not perform optimally in all..

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Cytokine adsorption correlates with lower circulating nucleosomes and is associated with decreased primary graft dysfunction

Abstract Elevated levels of neutrophil extracellular traps (NETs) have been reported in primary graft dysfunction, making methods to reduce or remove them highly valuable. The mechanisms behind primary graft dysfunction..

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Five commercial ‘depth of anaesthesia’ monitors provide discordant clinical recommendations in response to identical emergence-like EEG signals

Abstract Background ‘Depth of anaesthesia’ monitors claim to measure hypnotic depth during general anaesthesia from the EEG, and clinicians could reasonably expect agreement between monitors if presented with the same..

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Unleashing the Power of Gamification

Curious about why we chose to develop a video game instead of a mere online simulator? We receive this question frequently, so let us share with you a few compelling..

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The use of artificial intelligence for automating or semi-automating biomedical literature analyses: A scoping review

Abstract Objective Evidence-based medicine (EBM) is a decision-making process based on the conscious and judicious use of the best available scientific evidence. However, the exponential increase in the amount of..

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Nonischemic Donor Heart Preservation: New Milestone in Heart Transplantation History

Abstract Heart transplantation is considered the gold standard for the treatment of advanced end-stage heart failure. However, standard donors after brain death are decreasing, whereas patients on the heart transplant waitlist are..

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Technical considerations for percutaneous pulmonary artery cannulation for mechanical circulatory support

Abstract Objectives Percutaneous pulmonary artery cannulas, used as inflow for left ventricular venting or as outflow for right ventricular mechanical circulatory support, are easily and rapidly deployable with transesophageal and..

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Recommendations for developing effective and safe paediatric and congenital heart disease services in low-income and middle-income countries: a public health…

Abstract The global burden of paediatric and congenital heart disease (PCHD) is substantial. We propose a novel public health framework with recommendations for developing effective and safe PCHD services in low-income..

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Application of 1,000 fps High-Speed Angiography to In-Vitro Hemodynamic Evaluation of Left Ventricular Assist Device Outflow Graft Configurations

Abstract Left ventricular assist device (LVAD)–induced hemodynamics are characterized by fast-moving flow with large variations in velocity, making quantitative assessments difficult with existing imaging methods. This study demonstrates the ability of..

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Using Cardiohelp, Quadrox, and Nautilus Extracorporeal Membrane Oxygenators as Vascular Access for Hemodialysis, Continuous Renal Replacement Therapy, and Plasmapheresis: A…

Abstract The use of intermittent hemodialysis (iHD), and continuous renal replacement therapy (CRRT), along with extracorporeal membrane oxygenation (ECMO) in patients with acute kidney injury (AKI) and end-stage renal disease (ESRD) is..

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Ultrafiltration in cardiac surgery: Results of a systematic review and meta-analysis

Abstract Background:   Ultrafiltration is used with cardiopulmonary bypass to reduce the effects of hemodilution and restore electrolyte balance. We performed a systematic review and meta-analysis to analyze the effect..

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Analysis of perioperative corticosteroid therapy in children undergoing cardiac surgery: A systematic review and meta-analysis

Abstract The advantages and disadvantages of using corticosteroids in children undergoing cardiac surgery is still contentious. To examine how perioperative corticosteroids affect postoperative mortality and clinical outcomes in pediatric cardiac..

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A norepinephrine weaning strategy using dynamic arterial elastance is associated with reduction of acute kidney injury in patients with vasoplegia…

Abstract Study objective To evaluate the impact of a dynamic arterial elastance guided  weaning strategy on the occurrence of  (AKI) in  with  after cardiac surgery. Design A post-hoc analysis of a monocentric . Setting A..

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Timing of elective surgery and risk assessment after SARS-CoV-2 infection: an update

Abstract The impact of vaccination and new SARS-CoV-2 variants on peri-operative outcomes is unclear. We aimed to update previously published consensus recommendations on timing of elective surgery after SARS-CoV-2 infection..

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The American Association for Thoracic Surgery (AATS) 2022 Expert Consensus Document: The use of mechanical circulatory support in lung transplantation

Abstract Objective The use of mechanical circulatory support (MCS) in lung transplantation has been steadily increasing over the prior decade, with evolving strategies for incorporating support in the preoperative, intraoperative,..

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Implementation of the Kidney Disease Improving Global Outcomes guidelines for the prevention of acute kidney injury after cardiac surgery

Abstract BACKGROUND  Increasing evidence from randomised controlled trials supports the implementation of a six-measure care bundle proposed by the Kidney Disease Improving Global Outcomes (KDIGO) guidelines in patients at high..

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Assessing Risk Factors for Prolonged Intensive Care Unit Stay After Surgery for Adult Congenital Heart Disease: A Study From a…

Abstract Background Prolonged post-surgery intensive care unit (ICU) stay for congenital heart disease (CHD) has been explored in the pediatric population. However, there is limited data for adult CHD (ACHD),..

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Large volume acute normovolemic hemodilution in patients undergoing cardiac surgery with intermediate-high risk of transfusion: A randomized controlled trial

Abstract Study Objective: To investigate whether large volume acute normovolemic  (L-ANH), compared with moderate acute normovolemic  (M-ANH), can reduce perioperative allogeneic   with intermediate-high risk of transfusion during cardiac surgery with  (CPB). Design: Prospective . Setting:..

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Is Fasciotomy Associated With Increased Mortality in Extracorporeal Cardiopulmonary Resuscitation?

Abstract Our primary objective was to identify if fasciotomy was associated with increased mortality in patients who developed acute compartment syndrome (ACS) on extracorporeal cardiopulmonary resuscitation (ECPR). Additionally, we sought to identify any additional risk factors..

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Absolute Versus Relative Near-Infrared Spectroscopy in Pediatric Cardiac Patients

Abstract OBJECTIVES:  Near-infrared spectroscopy (NIRS) has been increasingly accepted as a noninvasive marker of regional tissue oxygenation despite concerns of imprecision and wide limits of agreement (LOA) with invasive oximetry. New generation absolute..

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“Beyond waking and walking. Intensive rehabilitation in patients requiring extended durations of advanced mechanical circulatory support: A case series”

Abstract Background: Physical therapy (PT) utilization in patients requiring mechanical circulatory support (MCS) and extracorporeal membrane oxygenation (ECMO) has been reported; however, little is known about intensive rehabilitation and associated..

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Deciding When to Start Renal Replacement Therapy After Cardiac Surgery in Real Life

Abstract Acute kidney injury (AKI) is a frequent complication of cardiac surgery that contributes to postoperative morbidity and mortality. The timing of renal replacement therapy (RRT) remains unclear. The Artificial..

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Perioperative Gelatin Use Is Associated With Increased Complication Rates and Does Not Prevent Postoperative Fluid Overload in Patients Undergoing Elective…

Abstract Objectives The benefit of using gelatin solution in cardiac surgery is still controversial. Previous data suggested adverse interactions of gelatin infusion with  (AKI) or . The purpose of this study was..

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Escalation and Withdrawal of Treatment for Patients on Extracorporeal Membrane Oxygenation

Abstract Objective:  The aim of this study was to describe decisions about the escalation and withdrawal of treatment for patients on extracorporeal membrane oxygenation (ECMO). Summary Background Data:  Interventions premised..

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The comparison of three different acute kidney injury classification systems after congenital heart surgery

Abstract Background We aimed to compare the frequency of acute kidney injury (AKI) and its effects on mortality and morbidity with different classification systems in pediatric patients who had surgery..

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Epidemiology of Neonatal Acute Kidney Injury After Cardiac Surgery Without Cardiopulmonary Bypass

Abstract Background The purpose of this Neonatal and Pediatric Heart and Renal Outcomes Network study was to describe the  and outcomes of cardiac surgery–associated  (CS-AKI) after cardiac surgery without  (non-CPB). Methods We performed..

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Cost-effectiveness of bivalirudin in pediatric ventricular assist devices

Abstract Background Despite recent data suggesting improved outcomes with bivalirudin vs heparin in pediatric Ventricular assist devices (VAD), higher costs remain a barrier. This study quantified trends in bivalirudin use..

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Skin colour affects the accuracy of medical oxygen sensors

Abstract The pulse oximeter is a device that estimates a person’s oxygen saturation level, a measure of the oxygen concentration in their blood, by shining light through their tissue, typically..

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Association of Preoperative Pulse Pressure and Oxygen Delivery Index During Cardiopulmonary Bypass With Postoperative Acute Kidney Injury

Abstract Objective To investigate if oxygen delivery index during  (DO2I) was more strongly associated with  (AKI), the higher the patient's preoperative pulse pressure (PP). Design Retrospective cohort of 1064 patients undergoing cardiac..

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Venovenous extracorporeal membrane oxygenation promotes alveolar epithelial recovery by activating Hippo/YAP signaling after lung injury

Abstract Background The preferred configuration for bridging patients with respiratory failure while awaiting  is venovenous  (VV ECMO). However, the protective effect of VV ECMO on the lung, as well as the underlying..

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