Yearly Archives: 2026

Perfusfind S.L.

Abstract Hospital-acquired infection (HAI) is a major complication in pediatric patients on extracorporeal membrane oxygenation (ECMO) and continuous renal replacement therapy (CRRT). Infection detection is challenging, as traditional inflammatory markers..

Perfusfind S.L.

Abstract Objectives Patients admitted to ICUs are frequently exposed to disrupted light–dark cycles due to limited daylight exposure and inappropriate electrical lighting in terms of intensity, duration, timing, and spectral..

Perfusfind S.L.

Managing refractory 𝐡𝐲𝐩𝐨𝐱𝐞𝐦𝐢𝐚 𝐨𝐧 𝐕𝐕 𝐄𝐂𝐌𝐎 isn't just about protocols— it's about making the right decisions at the right time. Join this live interactive 𝐄𝐂𝐌𝐎 𝐬𝐢𝐦𝐮𝐥𝐚𝐭𝐢𝐨𝐧 𝐰𝐞𝐛𝐢𝐧𝐚𝐫 and gain practical..

Perfusfind S.L.

Abstract Objectives Cardiopulmonary bypass (CPB) impairs endothelial function, causing oedema and disturbed microcirculatory perfusion, that contribute to organ dysfunction following cardiac surgery. We hypothesised that the composition of CPB prime..

Perfusfind S.L.

Abstract Background Patient Blood Management (PBM) is a multidisciplinary strategy to optimise patient outcomes by preserving autologous blood and reducing unnecessary transfusion. Although PBM initiatives exist worldwide, the consistency of..

Perfusfind S.L.

Abstract Pediatric patients undergoing cardiac catheterization are at risk of major adverse events, including cardiac arrest and the need for extracorporeal membrane oxygenation support. The primary aim of this study..

Perfusfind S.L.

Abstract Background Veno-arterial extracorporeal membrane oxygenation (V-A ECMO) is used for refractory cardiogenic shock, yet optimal weaning strategies and the role of left ventricular (LV) venting remain unclear. The TWEET-1..

Perfusfind S.L.

Abstract This review explores the regulatory mechanism of anesthesia on the perioperative immune response and its impact on postoperative recovery and complications in patients. Surgical trauma can activate the body's..

Perfusfind S.L.

Abstract Coagulopathy, bleeding, and transfusion of allogeneic blood products remain major concerns in a relevant portion of patients undergoing cardiac surgery, and all of them have been associated with increased..

Perfusfind S.L.

Abstract Background Patients receiving extracorporeal membrane oxygenation (ECMO) are considered nutritionally vulnerable, with previous studies focussed on Intensive Care Unit (ICU) admission alone. We aimed to address this gap by..

Perfusfind S.L.

Abstract Objective To evaluate the feasibility and diagnostic yield of universal genome sequencing (GS) in infants receiving extracorporeal membrane oxygenation (ECMO). Study design Prospective multicenter study across eight Children’s Hospital..

Perfusfind S.L.

Abstract Anthropogenic climate change is evident, and its impacts are being felt around the globe. The World Health Organization (WHO) recently revealed that approximately one in four deaths can be..

Perfusfind S.L.

Abstract The integration of artificial intelligence (AI) into medical training is accelerating faster than the educational frameworks designed to govern it. This Perspective identifies a risk that has received insufficient..

Perfusfind S.L.

Abstract Study Question To describe the blood product utilization during neonatal and pediatric extracorporeal membrane oxygenation (ECMO) and to determine whether its usage correlates with clinical outcomes of bleeding, thrombosis..

Perfusfind S.L.

Abstract The global rise in anticoagulant use has increased the number of major bleeding events that warrant timely and effective pharmacologic reversal. Reversal strategies should be informed by the pharmacodynamic..

Perfusfind S.L.

Abstract Importance  Neurodevelopmental impairments are common in children with congenital heart disease. Objectives  To compare neurodevelopmental outcomes by cardiac diagnosis and identify associations between medical and social factors and early neurodevelopmental outcomes..

Perfusfind S.L.

Abstract Cardiopulmonary bypass (CPB) activates a well-characterised systemic inflammatory response that contributes substantially to postoperative morbidity and mortality, particularly in high-risk patient subgroups. CytoSorb® (CytoSorbents Corporation, Princeton, NJ) is a..

Perfusfind S.L.

Abstract Open-heart surgery with cardiopulmonary bypass (CPB) is a high-risk procedure with significant morbidity and mortality. CPB, tissue injury, blood loss, endotoxemia and ischemia–reperfusion injury induce a pronounced systemic inflammatory..

Perfusfind S.L.

Abstract Introduction Intensive care units (ICUs) represent high-risk environments for adverse events (AEs). Preventing these events requires a solid understanding of their epidemiology based on standardized and validated methodologies. The..

Perfusfind S.L.

Abstract Background: Invasive ventilation saves lives but carries major risks, including ventilation-associated lung damage and long-term functional impairment. Data from recent studies compel reassessment of the evidence for every step of..

Perfusfind S.L.

Abstract Extracorporeal life support (ECLS) components designed to reduce clot formation have been developed, but thrombosis remains a significant challenge, requiring systemic anticoagulation. To address this, we evaluated a nitric..

Perfusfind S.L.

Abstract Objective To assess the non-inferiority of topical intrapericardial tranexamic acid (TXA) versus intravenous TXA for efficacy and safety in patients undergoing cardiac surgery with cardiopulmonary bypass (CPB). Methods In..

Perfusfind S.L.

Abstract Transfusions are one of the most common procedures performed in the hospital setting, but the frequency of adverse events is often not recognized. These transfusion adverse events include transfusion..

Perfusfind S.L.

Abstract Background Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) provides crucial circulatory and respiratory support in refractory cardiogenic shock and cardiac arrest. However, peripheral VA-ECMO increases left ventricular (LV) afterload through retrograde..

Perfusfind S.L.

Abstract Purpose of review The use of life-support therapies like extracorporeal membrane oxygenation (ECMO), mechanical circulatory systems (MCS), and continuous renal replacement therapy (CRRT) creates a complex and dynamic metabolic..

Perfusfind S.L.

Abstract Intestinal ischemia/reperfusion (I/R) injury is a critical clinical syndrome precipitated by the restoration of blood flow following intestinal ischemia, a common occurrence in perioperative settings such as abdominal aortic..

Perfusfind S.L.

Abstract Background Despite recent advancements in cardiopulmonary resuscitation (CPR), the prognosis of out-of-hospital cardiac arrest (OHCA) remains poor. Extracorporeal cardiopulmonary resuscitation (ECPR) offers potential benefits to improve outcomes of patients..

Perfusfind S.L.

Abstract Patient Blood Management (PBM) has evolved from a transfusion-centered practice to a structured, patient-focused perioperative strategy aimed at improving surgical outcomes while preserving blood resources. In the operating room,..

Perfusfind S.L.

Abstract Objective Prolonged ischemic time remains a major barrier to donor use and is strongly associated with primary graft dysfunction in heart transplantation. We evaluated whether intraoperative recipient metabolic adequacy,..

Perfusfind S.L.

Abstract Background Traumatic or surgical hemorrhage causes substantial morbidity and mortality. Electrical vagus nerve stimulation (VNS) reduces traumatic hemorrhage in animal models. VNS targets acetylcholine-producing T lymphocytes in the spleen..