Abstract BACKGROUND: Penetrating cardiac injuries caused by firearms are associated with extremely high prehospital and early in-hospital mortality. During wartime, civilian cardiac surgery centers are increasingly involved in the management..
Read MoreAbstract Background Patients supported with extracorporeal membrane oxygenation (ECMO) are susceptible to healthcare-associated infections (HAIs), which may worsen outcomes. However, epidemiological data from Latin American centres remain scarce. Methods We..
Read MoreAbstract In cardiogenic shock (CS), blood lactate concentration is routinely used to assess shock severity and guide clinical decisions. However, lactate interpretation is often oversimplified, leading to confusion between disease..
Read MoreAbstract Congenital heart disease often requires early surgical intervention. Cardiopulmonary bypass (CPB) is a standard procedure, but infants undergoing CPB show an increased risk of postoperative white matter injury. These..
Read MoreAbstract Although extracorporeal membrane oxygenation (ECMO) has emerged as a pivotal temporary extracorporeal life support in critically ill patients, it is associated with a high risk of mortality. Establishing a..
Read MoreAbstract Objective To characterize relationships between social determinants of health (SDoH) and mortality among infants receiving extracorporeal membrane oxygenation (ECMO). Study design Retrospectively, we identified infants born >34weeks gestation and..
Read MoreAbstract We present the first characterization of multiple organ dysfunction (OD) patterns and their associations with in-hospital mortality for children on extracorporeal membrane oxygenation (ECMO). We retrospectively assessed OD for..
Read MoreAbstract Acute kidney injury (AKI) and fluid accumulation (FA) are common during extracorporeal membrane oxygenation (ECMO) support and are associated with increased morbidity and mortality. Despite their clinical importance, contemporary..
Read MoreAbstract Background Extracorporeal cardiopulmonary resuscitation (ECPR) is increasingly used for refractory paediatric in-hospital cardiac arrest (IHCA). Although rapid initiation of extracorporeal life support (ECLS) is widely considered critical, the relative..
Read MoreAbstract Intraoperative adverse events (IAEs) are a significant unresolved problem in surgery. Breakdown in nontechnical skills (NTS) of surgical team members are a significant contributor to preventable IAEs [], Surgical..
Read MoreAbstract Artificial intelligence (AI) has rapidly emerged as a transformative force across multiple scientific and clinical domains, demonstrating remarkable capabilities in data analysis, pattern recognition, and predictive modeling. In the..
Read MoreAbstract Background Extracorporeal circulation (ECC) is increasingly supported by biomaterials engineered to minimize chemical leaching, and many biomedical manufacturers have now removed or substantially reduced phthalate plasticizers particularly di(2-ethylhexyl) phthalate..
Read MoreAbstract Background Acute kidney injury is a common complication of cardiac surgery and may lead to kidney failure. In a large sample sourced from national registries, we estimated the risk..
Read MoreAbstract Introduction Bleeding and clotting phenotypes are common in patients supported with Extracorporeal Membrane Oxygenation (ECMO) and are associated with increased mortality. However, tools to distinguish bleeding from clotting phenotypes..
Read MoreAbstract Factor XIII (FXIII) contributes to clot stability and reduces clot susceptibility to lysis through fibrin cross-linking. Standard coagulation tests like prothrombin time and activated partial thromboplastin time do not..
Read MoreAbstract Background and Objectives: Overt perioperative stroke remains a feared complication of adult cardiac surgery. Diffusion-weighted magnetic resonance imaging (DWI-MRI) has revealed a more prevalent form of cerebral injury, termed..
Read MoreAbstract Decompensated differential carbon dioxide (CO2) removal can occur during spontaneous breathing on peripheral venoarterial extracorporeal membrane oxygenation (V-A ECMO) when a low right radial arterial partial pressure of carbon..
Read MoreAbstract Objective Myocardial protection research in adult cardiac surgery has increasingly examined single dose del Nido cardioplegia alongside conventional multidose blood cardioplegia. Using a scientometric modeling approach, this study aims..
Read MoreAbstract Aim Acute kidney injury (AKI) is a major complication of coronary artery bypass grafting (CABG). Existing predictive models show limited accuracy and rarely include modifiable intraoperative risk factors. Therefore,..
Read MoreAbstract Background/Objectives: Volatile anesthetic dosing during cardiopulmonary bypass (CPB) is poorly standardized. We estimated the end-tidal sevoflurane (ETsevo) concentration required to maintain adequate anesthesia during CPB and investigated the effects..
Read MoreAbstract Background Acute myocardial infarction-related cardiogenic shock (AMI-CS) remains associated with extremely high mortality in patients with acute myocardial infarction despite timely revascularization and advances in mechanical circulatory support (MCS)...
Read MoreAbstract Introduction Early detection of acute brain injury (ABI) in patients on venoarterial extracorporeal membrane oxygenation (VA ECMO) is challenging. We aimed to investigate if heart rate variability (HRV) in..
Read MoreAbstract Background/Objectives: Acute kidney injury (AKI) remains a significant complication following cardiac surgery, associated with increased morbidity and mortality. The early detection of AKI is limited by the cost, availability,..
Read MoreAbstract Despite the advances in technology, new patient populations, new medications, and multiple monitoring algorithms for anticoagulation, bleeding, and thrombosis complications remain high among those receiving extracorporeal life support (ECLS)..
Read MoreAbstract Extracorporeal membrane oxygenation (ECMO) has increasingly been used in patients with refractory severe cardiorespiratory failure in recent years. The use of ECMO necessitates anticoagulation as blood passes through an..
Read MoreAbstract Background Accidental hypothermia is the unintentional decrease in core body temperature below 35°C due to environmental exposure. Severe hypothermia, defined as a core body temperature less than 28°C, can..
Read MoreAbstract Background and Aims Extracorporeal life support (ECLS) is a critical intervention in the management of severe cardiac and respiratory failure. Among the commonly used cannulation techniques, percutaneous cannulation (PC)..
Read MoreAbstract Extracorporeal life support provides temporary cardiorespiratory support for patients with severe, potentially reversible cardiac and/or respiratory failure refractory to conventional measures. Its application has broadened across a wide spectrum..
Read MoreAbstract Extracorporeal cardiopulmonary resuscitation (ECPR) for pediatric cardiac arrest relies on enhanced resources and time-critical decision-making. We aimed to evaluate variations in systems and clinical practice among extracorporeal membrane oxygenation..
Read MoreWatch our webinar on Perfusion in ECMO Practice Webinar: 1. Understanding the ECMO Circuit: Optimising Performance • Overview of ECMO circuit components and physiology • Flow, pressure, and oxygenation optimisation • Perfusionist best practices in..
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