Yearly Archives: 2026

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Effects of In-House Cryoprecipitate Use on Transfusion Volume for Cardiopulmonary Bypass Surgery

Abstract Purpose: Cryoprecipitate has been covered by Japanese national health insurance since 2020 for cardiopulmonary bypass (CPB)-induced hypofibrinogenemia. This study evaluated the clinical efficacy of in-house cryoprecipitate use in patients..

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Elective Cardiopulmonary Bypass (CPB) Surgery After COVID-19: Vasoactive Needs and Early Complications—A Prospective Study

Abstract Background/Objectives: Whether a remote history of SARS-CoV-2 infection independently affects early haemodynamic stability after elective cardiopulmonary bypass (CPB) remains uncertain. We evaluated whether prior COVID-19 (>7 weeks before surgery)..

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Acute Kidney Injury in Cardiac Surgery: A Comprehensive Review of Perioperative Strategies and Emerging Biomarkers

Abstract Acute kidney injury (AKI) is a significant complication following cardiac surgery, affecting 20% to 30% of patients and contributing to increased morbidity and mortality. Cardiac surgery–associated AKI (CSA-AKI) is..

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Targeted Albumin Administration in Cardiac Surgery: Refining Perioperative Fluid Strategy

Abstract Cardiac surgery poses specific challenges in fluid management. The role of albumin administration during cardiac surgery has long been controversial. Although it has theoretical advantages, it is expensive and..

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Renal vein congestion aggravates renal injury associated with cardiopulmonary bypass

Abstract Background Elevated central venous pressure during cardiac surgery can lead to increased renal venous pressure, subsequently resulting in renal insufficiency. However, there is a lack of animal models available..

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The Role of Aminothiols as Biomarkers of Oxidative Stress and Clinical Outcomes in Coronary Artery Bypass Grafting (CABG): A Narrative…

Abstract This narrative review summarizes current evidence on the role of aminothiols as biomarkers of oxidative stress in patients undergoing coronary artery bypass grafting (CABG). CABG is accompanied by profound..

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Association between the gut microbiome and neurodevelopmental outcomes in infants with congenital heart disease: A prospective cohort study

Abstract Background Children with congenital heart disease are at risk for poor neurodevelopment. The gut microbiome may influence neurodevelopmental outcomes through the gut-brain axis. This study investigated the association of..

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Inhaled Milrinone in Weaning from Cardiopulmonary Bypass: A Case Study

Abstract Separation from cardiopulmonary bypass (CPB) is a critical phase of cardiac surgery, particularly in patients with pulmonary hypertension and right heart failure. Milrinone, a phosphodiesterase inhibitor, is often used..

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Vacuum-assisted venous drainage versus gravitational venous drainage in patients undergoing cardiac surgery: A meta-analysis

Abstract Introduction Vacuum-assisted venous drainage (VAVD) has been proposed as a better alternative option than conventional gravitational venous drainage (GVD) in cardiac surgery. However, the literature reports conflicting results between..

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Efficacy and safety of postoperative autologous blood transfusion in cardiac surgery (RESCUE): Rationale, design, and study protocol of a multicenter…

Abstract Background Postoperative bleeding is a major concern in cardiac surgery, often leading to significant transfusion requirements. Despite this high transfusion demand, the use of postoperative autologous blood transfusion (PABT)..

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Impact of Resident-Led Operating on Outcomes in Adult Cardiac Surgery: A 10-Year Propensity-Matched Analysis

Abstract Objectives Cardiac surgical training in today's day and age faces significant challenges, including declining operative volumes, increasing case complexity, transcatheter interventions, and shorter training programmes, amongst others. Although it..

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Iron-related protein in prediction of acute kidney injury in the pediatric population after cardiac surgery

Abstract Background Acute Kidney Injury (AKI) is a frequent post-operative complication following cardiac surgery in the clinical setting. Iron metabolism disorders are a key cause of kidney injury during the..

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Nitric oxide delivery into the sweep flow of ECMO systems: Technical challenges and solutions

Abstract Sweep gas nitric oxide (sNO) is emerging as an adjunctive therapy, which may have positive impacts on thrombosis and inflammation during ECMO treatment. sNO is administered to the gas..

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The “Heart-and-Brain Interaction” in Newborns with Complex Congenital Heart Disease

Abstract Objectives Neonates with complex congenital heart disease (CHD), in particular newborns with hypoplastic left heart syndrome (HLHS) or transposition of the great arteries (TGA), may show brain pathologies and..

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Revisiting the safety of intraoperative cell salvage in cancer surgery: how to evaluate the functional properties of remaining cancer cells

Abstract Cancer surgery accounts for a substantial proportion of allogeneic blood use. As demographic changes lead to a growing number of oncologic procedures, transfusion demands are increasing, while blood supply..

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Pediatric Perfusion Retreat 2026 - Oct 9/10

Time & Location Oct 09, 2026, 3:00 PM – Oct 10, 2026, 4:30 PM Atlanta, 2220 N Druid Hills Rd NE, Atlanta, GA 30329, USA

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ECPR in the futile traumatic patient: breaking paradigms or fanciful optimism?

Abstract Many of us have looked at the dying trauma patient and wondered: why can’t we do better? The pathology is often deceptively simple—either there’s not enough circulating blood volume or a..

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Call for Standardized Intraoperative Weaning and Decannulation Practices in Venoarterial ECMO: Need for Consensus and Clinical Guidelines

Abstract Assessment of readiness for venoarterial extracorporeal membrane oxygenation (VA ECMO) weaning relies on hemodynamic and metabolic parameters of cardiac and respiratory functions. Lactate clearance, inotropic support, and echocardiographic criteria,..

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Perioperative Acute Kidney Injury: What’s New in 2025?

Abstract Perioperative acute kidney injury (AKI) is a frequent complication that affects outcomes well beyond the perioperative period. Its mechanisms remain incompletely understood, arising from the interplay of comorbidities, surgical..

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Preoperative untargeted SPME-LC/HRMS-based metabolomic profiling in cardiac surgical patients identified prognostic biomarkers for postoperative outcomes

Abstract Background Circulating metabolite profiles may reflect the physiological status before cardiac surgery and could contribute to predicting clinical outcome. Accordingly, metabolite levels may improve risk models as clinical models..

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Elevated oxygen extraction during heart transplantation is associated with increased morbidity and mortality: Implications for goal-directed perfusion

Abstract Background Goal-directed perfusion (GDP) during cardiopulmonary bypass (CPB) commonly targets indexed oxygen delivery (DO2i), yet fixed delivery thresholds may ignore patient-specific metabolic demand. The oxygen extraction ratio (O2ER) integrates..

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A Perioperative Blood Conservation Protocol to Achieve Successful Bloodless Heart Transplantation

Abstract Heart transplantation (HT) is the definitive therapy for end-stage heart failure. Patients unwilling to receive blood product transfusions are often considered ineligible for HT due to the significant perioperative..

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Training communication skills in a multiuser medical virtual reality simulation: a qualitative, observational study

Abstract Background Simulation-based education is a well-established training technique in medical curricula, also for communication skills. Virtual reality (VR) technology can enhance this form of experience-based learning. How VR interacts..

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Modified cardiac power output as a marker for left ventricular recovery during V-A ECMO

Abstract Dear Editor, The timely liberation of cardiogenic shock (CS) patients from veno-arterial extracorporeal membrane oxygenation (V-A ECMO) is crucial to reduce device  complications, although the predictor of weaning is..

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Pharmacological Research Agenda on Adult Extracorporeal Membrane Oxygenation Using the Delphi Method: A Position Paper of the Extracorporeal Membrane Oxygenation…

Abstract OBJECTIVES:  Extracorporeal membrane oxygenation (ECMO) is a critical intervention for patients with severe cardiac or respiratory failure. However, pharmacological management for ECMO-supported patients presents unique challenges due to alterations..

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Neuromonitoring Techniques in ECMO

Abstract Extracorporeal membrane oxygenation (ECMO) is a critical life-support therapy for patients with severe cardiac and/or respiratory failure, but it carries a significant risk of neurological complications. This narrative review..

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Continuous furosemide does not prevent cardiopulmonary bypass-related acute kidney injury in minimally invasive cardiac surgery: the randomized furosemide trial

Abstract Objectives: This study aimed to assess whether continuous furosemide administration during cardiopulmonary bypass (CPB) in minimally invasive cardiac surgery (MICS) reduces the incidence of cardiac surgery-associated acute kidney injury..

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UK multisociety consensus statement on the emergency management and resuscitation of patients with left-sided Impella support

Abstract The use of left-sided Impella microaxial flow pumps has expanded rapidly for the management of cardiogenic shock, left ventricular unloading and as a bridge to heart transplantation. However, standard..

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LVAD Implantation in Pediatric Population

LVAD Implantation in Pediatric Population inflow from LV and outflow to Ascending Aorta.   LVAD Implantation in the Pediatric Population   By Sam Zeraatiannejaddavani, MD   ⸻   A —..

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How to Prime an EVLP device

How to Prime an EVLP device from A to Z with back table LA and PA cuff srcuring and Dextran Priming as well connecting to EVLP.   Dr.Sam Zeraatian Nejad..

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