Yearly Archives: 2026

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Quantitative Evaluation of Hemolysis Under Excessive Static and Repeated Negative Pressure During Blood Handling

Abstract Background: Hemolysis, defined as the rupture of red blood cells (RBCs) with the release of hemoglobin into plasma, is a common concern during blood collection and extracorporeal circulation. Although..

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The Rate of Platelet Count Decline on Cardiopulmonary Bypass With a Sorin S5 Roller Pump

Abstract To the Editor: I wish to share the results of a retrospective observational correlation study I completed recently. While it is well established that the platelet count is negatively..

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Securing data management systems in perfusion: A narrative review on cybersecurity and clinical risk

Abstract Background The increasing digitization of perfusion practice has led to the integration of advanced data management systems (DMS) that record and analyze intraoperative variables in real time. While these..

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Unfractionated Heparin Dosing in Pediatric Venoarterial Extracorporeal Membrane Oxygenation: Single-Center Retrospective Study, 2015–2021

Abstract Objective:  Unfractionated heparin (UFH) is the most widely used anticoagulant during extracorporeal membrane oxygenation (ECMO). Optimal dosing of UFH for children undergoing ECMO is unknown, leading to suboptimal exposure...

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Characterization of PEG-Modified Composite Membranes for Microfluidic Oxygenator Applications

Abstract Microfluidic oxygenators promise to advance extracorporeal membrane oxygenation (ECMO) devices with enhanced hemodynamics and low prime volume. We are developing a silicon-based membrane oxygenator that will offer improved gas..

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Risk of Developing Lower Limb Ischemia in Patients With Extracorporeal Cardiopulmonary Resuscitation: A Secondary Analysis of the Study of Advanced…

Abstract Objectives:  While potential risks for limb ischemia have been explored in studies of venoarterial extracorporeal membrane oxygenation (ECMO), they remain inadequately defined for patients undergoing extracorporeal cardiopulmonary resuscitation (ECPR)...

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Automated Thromboelastometry for Semiquantitative Assessment of High Heparin Concentrations: A Feasibility Study in Healthy Volunteers

Abstract Background and Aims To date, thromboelastometry has not been investigated as an assay to monitor profound heparin anticoagulation, such as is required for a safe cardiopulmonary bypass (CPB). The..

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Role of Venoarterial Extracorporeal Membrane Oxygenation as a Procedural Support Tool in Cardiovascular Instability: A Case Series

Abstract The use of venoarterial extracorporeal membrane oxygenation (VA-ECMO) is increasing worldwide. Patients with cardiogenic shock were the first indication for VA-ECMO according to the Extracorporeal Life Support Organization (ELSO)..

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Venopulmonary extracorporeal life support: An Extracorporeal Life Support Organization registry analysis

Abstract Background There is a paucity of data informing on the current use, adverse events, outcomes, and prognostic drivers for patients receiving venopulmonary extracorporeal life support (VP ECLS). We aimed..

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Postoperative reduction in thrombin generation induced by elevated levels of tissue factor pathway inhibitor in cardiac surgery: a prospective observational…

Abstract Purpose Tissue factor pathway inhibitor (TFPI) is an intrinsic anticoagulant factor, and its plasma concentration is elevated by heparin administration. Because several hours are required to return to normal..

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Gender Disparity in Extracorporeal Cardiopulmonary Resuscitation for Out-of-Hospital Cardiac Arrest

Abstract Objectives:  Establishing an effective “chain of survival” for out-of-hospital cardiac arrest (OHCA) requires addressing gender disparities, which have been reported in both prehospital and in-hospital treatments. However, evidence of..

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Flow benefits of pediatric arterial cannulae versus introducer sheaths as distal perfusion catheters in venoarterial extracorporeal membrane oxygenation

Abstract Objective We test the hypothesis that pediatric arterial (“peds art”) cannulae as distal perfusion catheters (DPCs) for venoarterial extracorporeal membrane oxygenation provide more favorable distal limb hemodynamics than introducer..

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The Contemporary Landscape of Extracorporeal Membrane Oxygenation as a Bridge to Lung Transplantation

Abstract SINCE THE FIRST lung transplant in 1963 and the introduction of extracorporeal membrane oxygenation (ECMO) as a bridge to transplant (BTT) in 1977, both have advanced remarkably. Lung transplantation is now..

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Astrocyte Activation in the Hippocampus Following Cardiopulmonary Bypass in a Rat Model: A Pilot Study

Abstract Background: Delirium after cardiac surgery is associated with poor outcomes. Cardiopulmonary bypass (CPB) increases blood-brain barrier (BBB) permeability and neuroinflammation, contributing to delirium. While microglial activation after CPB has..

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Impact of different blood flow modes on hemodynamic environment, thrombosis risk and oxygen transport of oxygenators: A numerical simulation study

Abstract Background and Objective Pulsatile blood flow is considered more potential for delivering hemodynamic energy and enhancing microcirculatory perfusion in patients compared to non-pulsatile flow in ECMO. This study aims..

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Outcomes after postcardiotomy venoarterial extracorporeal membrane oxygenation in young patients: An individual patient data meta-analysis

Abstract Objective We aimed to evaluate the early and midterm mortality of young patients treated for cardiogenic shock with venoarterial extracorporeal membrane oxygenation (VA-ECMO) after adult cardiac surgery. Methods Studies..

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Platelet Transfusion Thresholds for Children Supported by Extracorporeal Membrane Oxygenation: The Extracorporeal Membrane Oxygenation Hemostatic Transfusions in Children (ECSTATIC) Feasibility…

Abstract Objectives:  To evaluate the feasibility of randomizing children on extracorporeal membrane oxygenation (ECMO) to one of two prophylactic platelet transfusion thresholds. Design:  Randomized controlled trial. Setting:  Ten ECMO centers..

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Role of Non-catecholamines Vasopressors in the Management of Vasoplegic Syndrome after Cardiopulmonary Bypass: A Scoping Review

Abstract Vasoplegic syndrome is a life-threatening condition characterized by uncontrolled peripheral vasodilation, leading to profound arterial hypotension. Treatments include catecholamines, vasopressin, methylene blue (MB), hydroxocobalamin, angiotensin II, and ascorbic acid...

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Autotransfusion in traumatic haemothorax using the Sinapi chest drain system

Abstract A previously well 23-year-old man presented to the Trauma Department of a large urban Level 1 Trauma Centre in South Africa. The patient sustained a stab wound to the..

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Healthcare professionals’ views on training, standards, and resources for extracorporeal membrane oxygenation: a cross-sectional survey

Abstract Aim To assess health care professionals’ knowledge and opinions regarding extracorporeal membrane oxygenation (ECMO) use, training, standards, and resource availability. Methods This cross-sectional study employed an online self-administered survey..

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Impact of Advanced Cardiac Life Support Medications on Discharge Neurological Function for Survivors of Cardiac Arrest When Using ECPR

Abstract BACKGROUND: While the immediate goal of cardiopulmonary resuscitation is to achieve return of spontaneous circulation, the patient-centered goal is to minimize neurological injury. Several medications used during cardiac arrest..

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Blood Conservation Protocol for Patients Undergoing Left Ventricular Assisted Device Implantation

Abstract Objectives:  This study aims to compare intraoperative blood transfusion and perioperative outcomes for patients undergoing left ventricular assist device (LVAD) implantation before and after the implementation of a blood..

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ABO-incompatible heart transplants in children aged 2-9 years: A new paradigm in transplant?

Abstract Background and Aims Pediatric heart transplantation remains hampered by the limited availability of donor organs. The introduction of ABO-incompatible (ABOi) heart transplantation for infants in the early 2000s expanded..

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Paris Ecmo simulation course - March / June

Two and half days entirely dedicated to practical VA and VV ECMO management, with numerous simulation sessions, practical hands-on, and discussion of concrete cases at the ICU bedside. This course is restricted to a maximum..

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National Heart Center Perfusion Guidelines

Abstract Objectives: To establish the first national standards and guidelines for best practice in perfusion for patients undergoing cardiothoracic surgery in Saudi Arabia. Cardiopulmonary bypass (CPB) enables complex cardiac surgeries;..

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Congreso de la Asociación Española de Perfusionistas 2026 - 10/12 Junio

  El Congreso de la AEP es una cita de referencia para los profesionales de la perfusión en España, orientada a la actualización científica, el intercambio de conocimiento y la..

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Incidence and Risk Factors of Limb Ischaemia in Adult Patients Receiving Veno-Arterial Extracorporeal Membrane Oxygenation: A Systematic Review and Meta-Analysis

Abstract Veno-arterial extracorporeal membrane oxygenation (V-A ECMO) has become an essential life-saving therapy for patients with refractory cardiogenic shock, cardiac arrest, and severe cardiopulmonary failure. Despite its expanding use and..

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Combined Inhaled Pulmonary Vasodilators in Cardiac Surgery: A Scoping Review

Abstract Pulmonary hypertension is a risk factor for increased morbidity and mortality in cardiac surgery. The use of a combination of inhaled vasodilator agents could have an improved effect on..

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Clinical Evaluation of the Hemostatic Efficacy and Safety of a Biodegradable Hemostatic Agent, Hemogram: A Comparative Study with Arista™ AH

Abstract Background Hemogram is a novel biodegradable powdered hemostatic agent developed by binding calcium ions (Ca²+) to carboxymethyl starch (CM-starch) and applying granulation technology to enhance blood absorption and hemostatic..

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Towards an understanding of best practice: The good, the bad and the future of cardiogenic shock teams

Abstract Cardiogenic shock (CS) remains a high-mortality condition that demands rapid diagnosis, coordinated multidisciplinary management, and timely initiation of mechanical circulatory support. As more institutions implement dedicated CS teams, substantial..

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