Abstract Background: Hemolysis, defined as the rupture of red blood cells (RBCs) with the release of hemoglobin into plasma, is a common concern during blood collection and extracorporeal circulation. Although..
Read MoreAbstract To the Editor: I wish to share the results of a retrospective observational correlation study I completed recently. While it is well established that the platelet count is negatively..
Read MoreSecuring data management systems in perfusion: A narrative review on cybersecurity and clinical risk
Abstract Background The increasing digitization of perfusion practice has led to the integration of advanced data management systems (DMS) that record and analyze intraoperative variables in real time. While these..
Read MoreAbstract Objective: Unfractionated heparin (UFH) is the most widely used anticoagulant during extracorporeal membrane oxygenation (ECMO). Optimal dosing of UFH for children undergoing ECMO is unknown, leading to suboptimal exposure...
Read MoreAbstract Microfluidic oxygenators promise to advance extracorporeal membrane oxygenation (ECMO) devices with enhanced hemodynamics and low prime volume. We are developing a silicon-based membrane oxygenator that will offer improved gas..
Read MoreAbstract Objectives: While potential risks for limb ischemia have been explored in studies of venoarterial extracorporeal membrane oxygenation (ECMO), they remain inadequately defined for patients undergoing extracorporeal cardiopulmonary resuscitation (ECPR)...
Read MoreAbstract Background and Aims To date, thromboelastometry has not been investigated as an assay to monitor profound heparin anticoagulation, such as is required for a safe cardiopulmonary bypass (CPB). The..
Read MoreAbstract The use of venoarterial extracorporeal membrane oxygenation (VA-ECMO) is increasing worldwide. Patients with cardiogenic shock were the first indication for VA-ECMO according to the Extracorporeal Life Support Organization (ELSO)..
Read MoreAbstract Background There is a paucity of data informing on the current use, adverse events, outcomes, and prognostic drivers for patients receiving venopulmonary extracorporeal life support (VP ECLS). We aimed..
Read MoreAbstract Purpose Tissue factor pathway inhibitor (TFPI) is an intrinsic anticoagulant factor, and its plasma concentration is elevated by heparin administration. Because several hours are required to return to normal..
Read MoreAbstract Objectives: Establishing an effective “chain of survival” for out-of-hospital cardiac arrest (OHCA) requires addressing gender disparities, which have been reported in both prehospital and in-hospital treatments. However, evidence of..
Read MoreAbstract Objective We test the hypothesis that pediatric arterial (“peds art”) cannulae as distal perfusion catheters (DPCs) for venoarterial extracorporeal membrane oxygenation provide more favorable distal limb hemodynamics than introducer..
Read MoreAbstract SINCE THE FIRST lung transplant in 1963 and the introduction of extracorporeal membrane oxygenation (ECMO) as a bridge to transplant (BTT) in 1977, both have advanced remarkably. Lung transplantation is now..
Read MoreAbstract Background: Delirium after cardiac surgery is associated with poor outcomes. Cardiopulmonary bypass (CPB) increases blood-brain barrier (BBB) permeability and neuroinflammation, contributing to delirium. While microglial activation after CPB has..
Read MoreAbstract Background and Objective Pulsatile blood flow is considered more potential for delivering hemodynamic energy and enhancing microcirculatory perfusion in patients compared to non-pulsatile flow in ECMO. This study aims..
Read MoreAbstract Objective We aimed to evaluate the early and midterm mortality of young patients treated for cardiogenic shock with venoarterial extracorporeal membrane oxygenation (VA-ECMO) after adult cardiac surgery. Methods Studies..
Read MoreAbstract Objectives: To evaluate the feasibility of randomizing children on extracorporeal membrane oxygenation (ECMO) to one of two prophylactic platelet transfusion thresholds. Design: Randomized controlled trial. Setting: Ten ECMO centers..
Read MoreAbstract Vasoplegic syndrome is a life-threatening condition characterized by uncontrolled peripheral vasodilation, leading to profound arterial hypotension. Treatments include catecholamines, vasopressin, methylene blue (MB), hydroxocobalamin, angiotensin II, and ascorbic acid...
Read MoreAbstract A previously well 23-year-old man presented to the Trauma Department of a large urban Level 1 Trauma Centre in South Africa. The patient sustained a stab wound to the..
Read MoreAbstract Aim To assess health care professionals’ knowledge and opinions regarding extracorporeal membrane oxygenation (ECMO) use, training, standards, and resource availability. Methods This cross-sectional study employed an online self-administered survey..
Read MoreAbstract BACKGROUND: While the immediate goal of cardiopulmonary resuscitation is to achieve return of spontaneous circulation, the patient-centered goal is to minimize neurological injury. Several medications used during cardiac arrest..
Read MoreAbstract Objectives: This study aims to compare intraoperative blood transfusion and perioperative outcomes for patients undergoing left ventricular assist device (LVAD) implantation before and after the implementation of a blood..
Read MoreAbstract Background and Aims Pediatric heart transplantation remains hampered by the limited availability of donor organs. The introduction of ABO-incompatible (ABOi) heart transplantation for infants in the early 2000s expanded..
Read MoreTwo and half days entirely dedicated to practical VA and VV ECMO management, with numerous simulation sessions, practical hands-on, and discussion of concrete cases at the ICU bedside. This course is restricted to a maximum..
Read MoreAbstract Objectives: To establish the first national standards and guidelines for best practice in perfusion for patients undergoing cardiothoracic surgery in Saudi Arabia. Cardiopulmonary bypass (CPB) enables complex cardiac surgeries;..
Read MoreEl Congreso de la AEP es una cita de referencia para los profesionales de la perfusión en España, orientada a la actualización científica, el intercambio de conocimiento y la..
Read MoreAbstract Veno-arterial extracorporeal membrane oxygenation (V-A ECMO) has become an essential life-saving therapy for patients with refractory cardiogenic shock, cardiac arrest, and severe cardiopulmonary failure. Despite its expanding use and..
Read MoreAbstract Pulmonary hypertension is a risk factor for increased morbidity and mortality in cardiac surgery. The use of a combination of inhaled vasodilator agents could have an improved effect on..
Read MoreAbstract Background Hemogram is a novel biodegradable powdered hemostatic agent developed by binding calcium ions (Ca²+) to carboxymethyl starch (CM-starch) and applying granulation technology to enhance blood absorption and hemostatic..
Read MoreAbstract Cardiogenic shock (CS) remains a high-mortality condition that demands rapid diagnosis, coordinated multidisciplinary management, and timely initiation of mechanical circulatory support. As more institutions implement dedicated CS teams, substantial..
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