Abstract Intestinal ischemia/reperfusion (I/R) injury is a critical clinical syndrome precipitated by the restoration of blood flow following intestinal ischemia, a common occurrence in perioperative settings such as abdominal aortic..
Read MoreAbstract Background Despite recent advancements in cardiopulmonary resuscitation (CPR), the prognosis of out-of-hospital cardiac arrest (OHCA) remains poor. Extracorporeal cardiopulmonary resuscitation (ECPR) offers potential benefits to improve outcomes of patients..
Read MoreAbstract Patient Blood Management (PBM) has evolved from a transfusion-centered practice to a structured, patient-focused perioperative strategy aimed at improving surgical outcomes while preserving blood resources. In the operating room,..
Read MoreAbstract Objective Prolonged ischemic time remains a major barrier to donor use and is strongly associated with primary graft dysfunction in heart transplantation. We evaluated whether intraoperative recipient metabolic adequacy,..
Read MoreAbstract Background Traumatic or surgical hemorrhage causes substantial morbidity and mortality. Electrical vagus nerve stimulation (VNS) reduces traumatic hemorrhage in animal models. VNS targets acetylcholine-producing T lymphocytes in the spleen..
Read MoreAbstract Background Discovered in 1938, haptoglobin is a liver-produced α2-glycoprotein that binds free hemoglobin, mitigating its toxic effects, and serves as a biomarker for hemolysis. The current study, under the..
Read MoreAbstract Background: Heparin-induced thrombocytopenia (HIT) in patients who undergo cardiac surgery presents unique diagnostic and management challenges due to universal perioperative heparin exposure, postoperative platelet kinetics, and the high prevalence..
Read MoreSurgical Procurement of a Donor Heart with Complex Congenital and Venous Anomalies: PLSVC, Coronary Sinus Dilation, RA Aneurysm, and Patent Ductus Arteriosus (PDA) In thoracic organ transplantation, discovering..
Read MorePartial Heart and Lung Transplantation: Maximizing Donor Organ Utilization Through Two-Recipient Transplantation Partial heart and lung transplantation is an innovative organ utilization strategy that allows transplantation of thoracic..
Read MoreManaging aortic and pulmonary root enlargement in donor organs requires a meticulous, proactive strategy to ensure structural stability before implantation into an emergency recipient. Utilizing a double..
Read MoreAbstract Background Jehova′s Witnesses refuse the administration of allogenic blood products for religious reasons. This stance represents a special challenge for the perioperative management and requires individualized ethically sensitive and..
Read MoreAbstract Background Congenital heart disease surgery includes intricate structures that are perhaps hard to completely understand by traditional two-dimensional shapes. Individualised, centre-based three-dimensional (3D) heart models may enhance structural imaging and..
Read MoreAbstract Rationale Circadian rhythms affect cardiovascular function, and the timing and severity of stroke and myocardial infarction (commonly known as a heart attack). Afternoon cardiac surgery may improve outcomes by..
Read MoreAbstract Background Oxygenator failure during cardiopulmonary bypass (CPB) is a rare but potentially catastrophic intraoperative event that can result in sudden hypoxemia and neurological injury if not promptly recognized and..
Read MoreAbstract Background Cardiac index (CI) and mean arterial pressure (MAP) are concurrent determinants of renal perfusion. Hypotension is associated with acute kidney injury (AKI), but clinical trials focused solely on..
Read MoreAbstract We describe a case of establishing cardiopulmonary bypass (CPB) before general anesthesia in a person who has an obstructive right atrial myxoma protruding into the right ventricle (RV). A..
Read MoreAbstract Background Thromboelastometry is often used to guide coagulation management, but validation outside cardiac surgery is limited. We evaluated correlations between thromboelastometry parameters and conventional laboratory tests in noncardiac patients..
Read MoreAbstract Purpose This study aimed to evaluate the clinical effects of sodium bicarbonate Ringer’s solution(BRS) as a priming fluid for cardiopulmonary bypass (CPB). Methods A total of 159 patients undergoing..
Read MoreAbstract Patient blood management (PBM) aims to improve patient outcome by managing and preserving a patient’s own blood and its components. Among the many recommended interventions, reducing intraoperative blood loss..
Read MoreAbstract Background In 2019, the American Society of Extracorporeal Technology (AmSECT) approved the inaugural Standards and Guidelines for Pediatric and Congenital Perfusion Practice. These standards and guidelines were created with the..
Read MoreAbstract Background: Postoperative thrombocytopenia is a frequent complication in cardiac surgery, associated with increased morbidity and mortality. Our study aimed to describe platelet count after cardiac surgery and identify predictors..
Read MoreAbstract Importance Timely identification of acute brain injury (ABI) in children receiving extracorporeal membrane oxygenation (ECMO) support is critical for early neuroprotective interventions. Objectives To determine if elevations in plasma glial fibrillary..
Read MoreAbstract Objectives To determine if the administration of coagulation products in cardiac surgery depends on the anesthesiologist’s exposure/number of cases per year, being on-call the same night as the surgery,..
Read MoreIntroduction Takayasu’s arteritis (TA) is an idiopathic vasculitis that mainly affects the aorta and its proximal branches. The female-to-male ratio is 8:1. The mean age at the time of diagnosis..
Read MoreAbstract Andexanet alfa (Ondexxya) currently holds UK marketing authorisation (MA) for adult patients treated with a direct factor Xa (FXa) inhibitor (apixaban or rivaroxaban) when reversal of anticoagulation is indicated..
Read MoreAbstract The integration of artificial intelligence (AI) into medical training is accelerating faster than the educational frameworks designed to govern it. This Perspective identifies a risk that has received insufficient..
Read MoreAbstract Background Postoperative delirium (POD) is a common complication of cardiac surgery with cardiopulmonary bypass (CPB), and it is associated with systemic inflammation and gut–brain axis dysregulation. This study investigated..
Read MoreAbstract Effective coagulation management is pivotal to optimizing outcomes in cardiac surgery, influencing bleeding risk, transfusion requirements, and overall perioperative safety. This comprehensive review examines current strategies, limitations, and emerging..
Read MoreAbstract Background The contact activation system is triggered when blood comes into contact with artificial surfaces. Cardiopulmonary bypass (CPB) induces such activation, however the extent of factor XII (FXII) reduction..
Read MoreAbstract Background: Cardiopulmonary bypass (CPB) is an essential technique for cardiac surgery but significantly increases the risk of perioperative neurological complications. Electroencephalography (EEG) enables real-time monitoring of brain function and..
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