Monthly Archives: julio 2026

thumbnail
0 comment

Intestinal Ischemia/Reperfusion Injury: Mechanisms, Diagnosis, and Therapeutic Advances

Abstract Intestinal ischemia/reperfusion (I/R) injury is a critical clinical syndrome precipitated by the restoration of blood flow following intestinal ischemia, a common occurrence in perioperative settings such as abdominal aortic..

Read More
thumbnail
0 comment

Impact of transient return of spontaneous circulation and downtime on neurological outcomes following extracorporeal cardiopulmonary resuscitation for refractory out-of-hospital cardiac…

Abstract Background Despite recent advancements in cardiopulmonary resuscitation (CPR), the prognosis of out-of-hospital cardiac arrest (OHCA) remains poor. Extracorporeal cardiopulmonary resuscitation (ECPR) offers potential benefits to improve outcomes of patients..

Read More
thumbnail
0 comment

Perioperative Patient Blood Management: Evidence-Based Strategies for Surgeons and Anesthesiologists: A Narrative Review

Abstract Patient Blood Management (PBM) has evolved from a transfusion-centered practice to a structured, patient-focused perioperative strategy aimed at improving surgical outcomes while preserving blood resources. In the operating room,..

Read More
thumbnail
0 comment

Low intraoperative oxygen extraction during heart transplant reduces primary graft dysfunction risk in allografts with prolonged ischemic time

Abstract Objective Prolonged ischemic time remains a major barrier to donor use and is strongly associated with primary graft dysfunction in heart transplantation. We evaluated whether intraoperative recipient metabolic adequacy,..

Read More
thumbnail
0 comment

Effects of transcutaneous auricular vagus nerve stimulation or combined vagal and trigeminal nerve stimulation on platelet function and laboratory hemostasis…

Abstract Background Traumatic or surgical hemorrhage causes substantial morbidity and mortality. Electrical vagus nerve stimulation (VNS) reduces traumatic hemorrhage in animal models. VNS targets acetylcholine-producing T lymphocytes in the spleen..

Read More
thumbnail
0 comment

Reference intervals for haptoglobin in neonates and children 30 days to 18 years old

Abstract Background Discovered in 1938, haptoglobin is a liver-produced α2-glycoprotein that binds free hemoglobin, mitigating its toxic effects, and serves as a biomarker for hemolysis. The current study, under the..

Read More
thumbnail
0 comment

2026 American Association for Thoracic Surgery Expert Consensus Document: Diagnosis and management of heparin-induced thrombocytopenia in patients who undergo cardiac…

Abstract Background: Heparin-induced thrombocytopenia (HIT) in patients who undergo cardiac surgery presents unique diagnostic and management challenges due to universal perioperative heparin exposure, postoperative platelet kinetics, and the high prevalence..

Read More
thumbnail
0 comment

Surgical Procurement of a Donor Heart with Complex Congenital and Venous Anomalies

    Surgical Procurement of a Donor Heart with Complex Congenital and Venous Anomalies: PLSVC, Coronary Sinus Dilation, RA Aneurysm, and Patent Ductus Arteriosus (PDA) In thoracic organ transplantation, discovering..

Read More
thumbnail
0 comment

Partial Heart and Lung Transplantation with Two Recipients from One Donor

    Partial Heart and Lung Transplantation: Maximizing Donor Organ Utilization Through Two-Recipient Transplantation Partial heart and lung transplantation is an innovative organ utilization strategy that allows transplantation of thoracic..

Read More
thumbnail
0 comment

Managing aortic and pulmonary root enlargement in donor organs

      Managing aortic and pulmonary root enlargement in donor organs requires a meticulous, proactive strategy to ensure structural stability before implantation into an emergency recipient. Utilizing a double..

Read More
thumbnail
0 comment

Perioperative blood management in Jehovah’s Witnesses

Abstract Background Jehova′s Witnesses refuse the administration of allogenic blood products for religious reasons. This stance represents a special challenge for the perioperative management and requires individualized ethically sensitive and..

Read More
thumbnail
0 comment

Impact of three-dimensional heart models on surgical planning and outcomes in congenital heart disease: a systematic review and meta-analysis

Abstract Background Congenital heart disease surgery includes intricate structures that are perhaps hard to completely understand by traditional two-dimensional shapes. Individualised, centre-based three-dimensional (3D) heart models may enhance structural imaging and..

Read More
thumbnail
0 comment

Early versus late surgical start times for on‐pump cardiac surgery

Abstract Rationale Circadian rhythms affect cardiovascular function, and the timing and severity of stroke and myocardial infarction (commonly known as a heart attack). Afternoon cardiac surgery may improve outcomes by..

Read More
thumbnail
0 comment

Early oxygenator failure during cardiopulmonary bypass with preserved neurological outcome: a case report

Abstract Background Oxygenator failure during cardiopulmonary bypass (CPB) is a rare but potentially catastrophic intraoperative event that can result in sudden hypoxemia and neurological injury if not promptly recognized and..

Read More
thumbnail
0 comment

Low cardiac index during periods of arterial hypotension and risk of acute kidney injury in cardiac surgery

Abstract Background Cardiac index (CI) and mean arterial pressure (MAP) are concurrent determinants of renal perfusion. Hypotension is associated with acute kidney injury (AKI), but clinical trials focused solely on..

Read More
thumbnail
0 comment

Establishing Cardiopulmonary Bypass Before General Anesthesia in a Patient Undergoing Right Atrial Myxoma Resection

Abstract We describe a case of establishing cardiopulmonary bypass (CPB) before general anesthesia in a person who has an obstructive right atrial myxoma protruding into the right ventricle (RV). A..

Read More
thumbnail
0 comment

A Retrospective Analysis of Thromboelastometry and Conventional Laboratory Values in Nonsurgical and Noncardiac Surgery Patients: Not What One Might Expect…

Abstract Background Thromboelastometry is often used to guide coagulation management, but validation outside cardiac surgery is limited. We evaluated correlations between thromboelastometry parameters and conventional laboratory tests in noncardiac patients..

Read More
thumbnail
0 comment

Effectiveness of sodium bicarbonate Ringer’s solution as a priming fluid for cardiopulmonary bypass: a propensity score matching study

Abstract Purpose This study aimed to evaluate the clinical effects of sodium bicarbonate Ringer’s solution(BRS) as a priming fluid for cardiopulmonary bypass (CPB). Methods A total of 159 patients undergoing..

Read More
thumbnail
0 comment

Combined Platelet and Red Blood Cell Salvage During Cardiac Surgery

Abstract Patient blood management (PBM) aims to improve patient outcome by managing and preserving a patient’s own blood and its components. Among the many recommended interventions, reducing intraoperative blood loss..

Read More
thumbnail
0 comment

The American Society of ExtraCorporeal Technology Standards and Guidelines for Pediatric and Congenital Perfusion Practice: 2025 Update

Abstract Background In 2019, the American Society of Extracorporeal Technology (AmSECT) approved the inaugural Standards and Guidelines for Pediatric and Congenital Perfusion Practice. These standards and guidelines were created with the..

Read More
thumbnail
0 comment

Thrombocytopenia After Cardiac Surgery: A Single-Center Retrospective Study

Abstract Background: Postoperative thrombocytopenia is a frequent complication in cardiac surgery, associated with increased morbidity and mortality. Our study aimed to describe platelet count after cardiac surgery and identify predictors..

Read More
thumbnail
0 comment

Plasma Biomarkers of Brain Injury in Critically Ill Children Receiving Extracorporeal Membrane Oxygenation

Abstract Importance  Timely identification of acute brain injury (ABI) in children receiving extracorporeal membrane oxygenation (ECMO) support is critical for early neuroprotective interventions. Objectives  To determine if elevations in plasma glial fibrillary..

Read More
thumbnail
0 comment

Influence of Human Factors on Coagulation Management in Cardiac Surgery: A Retrospective Analysis

Abstract Objectives To determine if the administration of coagulation products in cardiac surgery depends on the anesthesiologist’s exposure/number of cases per year, being on-call the same night as the surgery,..

Read More
thumbnail
0 comment

Perioperative Management and Surgical Approaches in a Rare Case of Coronary Artery Bypass Grafting Surgery in a Patient with Takayasu’s…

Introduction Takayasu’s arteritis (TA) is an idiopathic vasculitis that mainly affects the aorta and its proximal branches. The female-to-male ratio is 8:1. The mean age at the time of diagnosis..

Read More
thumbnail
0 comment

Use of andexanet alfa: A British Society for Haematology position statement

Abstract Andexanet alfa (Ondexxya) currently holds UK marketing authorisation (MA) for adult patients treated with a direct factor Xa (FXa) inhibitor (apixaban or rivaroxaban) when reversal of anticoagulation is indicated..

Read More
thumbnail
0 comment

AI-induced never-skilling in medical education

Abstract The integration of artificial intelligence (AI) into medical training is accelerating faster than the educational frameworks designed to govern it. This Perspective identifies a risk that has received insufficient..

Read More
thumbnail
0 comment

Intestinal microbiota dynamics in postoperative delirium following cardiac surgery with cardiopulmonary bypass: an observational study

Abstract Background Postoperative delirium (POD) is a common complication of cardiac surgery with cardiopulmonary bypass (CPB), and it is associated with systemic inflammation and gut–brain axis dysregulation. This study investigated..

Read More
thumbnail
0 comment

Comprehensive Coagulation Management in Cardiac Surgery: Anticoagulants, Heparin Resistance, Monitoring, and Bleeding Risks

Abstract Effective coagulation management is pivotal to optimizing outcomes in cardiac surgery, influencing bleeding risk, transfusion requirements, and overall perioperative safety. This comprehensive review examines current strategies, limitations, and emerging..

Read More
thumbnail
0 comment

FXII decline during cardiopulmonary bypass and the limits of routine coagulation assays: a prospective observational analysis

Abstract Background The contact activation system is triggered when blood comes into contact with artificial surfaces. Cardiopulmonary bypass (CPB) induces such activation, however the extent of factor XII (FXII) reduction..

Read More
thumbnail
0 comment

A Systematic Review of How Cardiopulmonary Bypass Parameters Influence Electroencephalogram Signals

Abstract Background: Cardiopulmonary bypass (CPB) is an essential technique for cardiac surgery but significantly increases the risk of perioperative neurological complications. Electroencephalography (EEG) enables real-time monitoring of brain function and..

Read More