Monthly Archives: junio 2026

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Core components of transitional care for ECMO survivors after ICU discharge: a three-round modified Delphi study

Abstract Background Survivors of extracorporeal membrane oxygenation (ECMO) may experience persistent physical, cognitive, psychological, social, and quality-of-life impairments after intensive care unit (ICU) discharge. However, the core components of early..

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Extracorporeal Membrane Oxygenation Combined With Mechanical Thrombectomy Versus Extracorporeal Membrane Oxygenation Alone for High-Risk Pulmonary Embolism: A Systematic Review and…

Abstract Objectives To compare clinical outcomes of venoarterial (VA) extracorporeal membrane oxygenation (ECMO) combined with mechanical thrombectomy (MT) versus VA-ECMO alone in high-risk pulmonary embolism (PE). Design Systematic review and..

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Evaluating the Clinical Significance of Pre- and Postoperative Platelet Function Testing in Coronary Artery Bypass Grafting Surgery

Abstract Background/Objectives: Postoperative bleeding remains a major complication following coronary artery bypass grafting (CABG), contributing to transfusion requirements, reintervention, and morbidity. The objective of this study was to assess the..

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Extracorporeal life support in adult critically ill patients: mechanisms of benefit in respiratory and cardiac failure

Abstract Extracorporeal life support provides temporary cardiorespiratory support for patients with severe, potentially reversible cardiac and/or respiratory failure refractory to conventional measures. Its application has broadened across a wide spectrum..

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Impact of Colloid Cardiopulmonary Bypass Priming Strategy on Perioperative Acid-Base Balance in Coronary Artery Bypass Surgery: Physicochemical Analysis of a…

Abstract Objective To determine whether colloid choice within the cardiopulmonary bypass (CPB) priming strategy independently modifies the perioperative acid-base trajectory. Design Preplanned analysis of a single-center, double-blind, 3-arm randomized controlled..

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Impact of microplastics and nanoplastics on cardiovascular health

Abstract Plastics serve multiple functions in an industrialized society, including major applications in all aspects of healthcare such as single use syringes, coatings and implantable devices. Plastics break down into..

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Glycocalyx degradation is associated with increased circulating unmeasured ions after cardiopulmonary bypass

Abstract Unmeasured anions are commonly detected in critically ill patients, yet their nature remains unclear. We examined whether endothelial glycocalyx degradation may be related to this unexplained anionic burden through..

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Awake venoarterial extracorporeal membrane oxygenation as a bridge to foetal maturation in severe pulmonary hypertension: a case report

Abstract A 37-year-old patient (gravida 10, para 0–1–8-0) with class III obesity, obstructive sleep apnoea requiring continuous positive airway pressure and previous pulmonary emboli presented at 19 + 6 weeks' gestation with severe..

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Pre‒Cardiopulmonary Bypass Furosemide Administration and Intraoperative Urinary Oxygen Tension During Coronary Artery Bypass Surgery: A Prospective Observational Study

Abstract Objectives To evaluate whether furosemide administration before cardiopulmonary bypass (CPB) is associated with altered intraoperative urinary oxygen tension (PuO₂) and early postoperative renal outcomes in patients undergoing elective on-pump..

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Risk factors for in-hospital mortality in elderly patients receiving veno-venous extracorporeal membrane oxygenation: A single-center retrospective study

Abstract Background Veno-venous extracorporeal membrane oxygenation (VV-ECMO) is an established therapy for severe respiratory failure; however, few studies have examined the validity of and prognostic factors for VV-ECMO implementation in..

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The Unknown Others of Neonatal Respiratory Extracorporeal Membrane Oxygenation

Abstract Increasingly, more neonatal respiratory extracorporeal membrane oxygenation (ECMO) patients in the Extracorporeal Life Support Organization (ELSO) registry have a primary diagnosis of Other. These patients, in addition to those..

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Oxygenation Indices with Oxygen Challenge Test in Neonates During VA ECMO

Abstract Objective: To evaluate the response of various oxygenation indices to the oxygen challenge test (OCT), prior to decannulation, in neonates supported with VA ECMO for respiratory indications, and to..

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Perioperative mechanical ventilation strategies in adult cardiac surgery with cardiopulmonary bypass: a meta-analysis of randomised controlled trials

Abstract Background Pulmonary complications occur frequently after cardiac surgery. Various intraoperative and perioperative mechanical ventilation strategies were investigated to reduce postoperative lung injury. Evidence of their benefits remains inconclusive. Methods..

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Progress in Understanding Brain Injury After Cardiopulmonary Bypass in Cardiac Surgery: A Narrative Review

Abstract The application of cardiopulmonary bypass (CPB) has significantly advanced cardiovascular surgery. However, CPB-associated brain injury remains a critical complication that affects patient prognosis and quality of life. Overt stroke..

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Noninvasive Respiratory Support Before Extracorporeal Membrane Oxygenation for Acute Respiratory Distress Syndrome: A Meta-Analysis

Abstract The optimal timing for transitioning from noninvasive respiratory support to invasive mechanical ventilation and extracorporeal membrane oxygenation (ECMO) in severe acute respiratory distress syndrome (ARDS) remains controversial. PubMed and..

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Open-access Cost-effectiveness of the timing of respiratory extracorporeal membrane oxygenation initiation in pediatric patients

Abstract Objective:  The aim of this study was to assess the cost-effectiveness of early versus late initiation of extracorporeal membrane oxygenation (ECMO) in pediatric patients with acute respiratory distress syndrome..

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Perioperative Antithrombin Activity and Postoperative Outcomes in Adult Cardiac Surgery: A Prospective Cohort in Contemporary Plasma-Sparing Practice

Abstract Objectives To determine whether low pre- or post-bypass antithrombin (AT) activity identifies adult cardiac surgery patients at increased risk of adverse outcomes in settings where plasma transfusion is rare...

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Progress Toward a Portable Artificial Lung: A Systematic Review

Abstract Background Chronic respiratory diseases are the third leading global cause of death. As lung transplantation is a definitive treatment for highly selected candidates, extracorporeal membrane oxygenation (ECMO) can be..

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Road Map of Extracorporeal Membrane Oxygenation in the Early Post–Lung Transplant Period

Abstract Extracorporeal membrane oxygenation is increasingly used in the early postoperative period after lung transplantation, mainly to support patients with primary graft dysfunction and severe right ventricular failure. Recipients with..

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Thermal heterogeneity after deep hypothermic circulatory arrest: a new framework for understanding rewarming and physiological recovery

Abstract Deep hypothermic circulatory arrest (DHCA) is widely used during complex aortic arch surgery to reduce metabolic demand and protect vital organs. Conventional temperature management assumes that restoration of core..

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Acute Severe Asthma in the Intensive Care Unit: From Bronchodilators to Extracorporeal Membrane Oxygenation

Abstract Acute severe asthma exacerbations are life-threatening critical care emergencies characterized by profound airflow obstruction, respiratory acidosis, and risk for cardiopulmonary arrest. For the purposes of this review, the term..

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Nurse-led acute care post-operative interventions in adult cardiac surgery: a systematic review

Abstract Aims The primary aim of this systematic review was to identify nurse-led clinical interventions evaluated in randomized controlled trials (RCTs) for adults who had undergone cardiac surgery. The secondary..

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The Perioperative Management of Cold-Induced Urticaria in Cardiac Surgery With Hypothermia on Cardiopulmonary Bypass

Abstract Cold-induced urticaria is a chronic urticaria subtype which can result in a severe, life-threating, anaphylaxis type reaction to cold stimuli. While a rare condition, it has potentially significant implications..

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Neuroprognostication After Extracorporeal Cardiopulmonary Resuscitation: ECMO-Specific Challenges and a Multimodal Time-Sensitive Framework

Abstract Extracorporeal cardiopulmonary resuscitation (ECPR) has emerged as a promising strategy for selected patients with refractory cardiac arrest, improving survival and the likelihood of favorable neurological outcomes. However, neurological prognostication..

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East-West Syndrome in Extracorporeal Membrane Oxygenation: Implications for Clinical Nursing Practice

Abstract As extracorporeal membrane oxygenation technology has evolved, interest in awake peripheral venoarterial extracorporeal membrane oxygenation has grown. This approach poses new challenges in patient monitoring. East-west syndrome is a..

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Severity and timing of elevated lactate correlates with mortality after cardiac surgery

Abstract Objective Extreme serum hyperlactatemia is common after cardiac surgery but can portend organ ischemia and mortality. Thus, we sought to determine which lactate thresholds warrant concern at various time..

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Experimental Extracorporeal Circulation System: A Pilot Study in Rats

Abstract Background Extracorporeal circulation (ECC) has become an important component in cardiac surgery, for cardiopulmonary support, and as a bridge to transplantation. Optimization of systems, components, and management requires further..

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Assessment of Microcirculation and Microcirculatory Function During Cardiopulmonary Bypass Using Hyperspectral Imaging and a Vascular Occlusion Test: An Observational Pilot…

Abstract Objectives To evaluate perioperative changes in cutaneous microcirculation and microvascular reactivity using hyperspectral imaging (HSI) with a standardized vascular occlusion test (VOT) in cardiac surgery with cardiopulmonary bypass (CPB),..

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In Situ Venous Cannula Puncture: A Simplified Technique for Extracorporeal Membrane Oxygenation Blood Salvage

Abstract Salvaging residual circuit blood upon extracorporeal membrane oxygenation (ECMO) discontinuation is a clinically valuable blood conservation strategy, mirroring standard cardiopulmonary bypass protocols. We describe a simplified technique using an..

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Randomized Clinical Trial Comparing Effects of Pulsatile vs Nonpulsatile Cardiopulmonary Bypass on Neurologic Outcomes

Abstract Background The objective of this secondary analysis was to examine the impact of 2 perfusion modalities on S100 calcium-binding protein B (S100B) levels and neural injury outcomes in patients..

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