Archivos anuales: 2025

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Minimally Invasive vs Conventional Coronary Bypass Surgery for Multivessel Coronary Disease

Abstract Background Despite sternum sparing and without cardiopulmonary bypass, the actual value of minimally invasive coronary surgery (MICS) is still debatable. This study aimed to compare the completeness of revascularization..

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Venovenous extracorporeal membrane oxygenation with mechanical chest compression for cardiopulmonary resuscitation: A porcine model study

Abstract Objective To evaluate the effectiveness of venovenous (VV) extracorporeal membrane oxygenation (ECMO) using a dual-lumen cannula coupled with continuous mechanical chest compressions (cMCC) for cardiopulmonary resuscitation and compare it..

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Hypotension During Cardioplegia Administration: Does the Route of Delivery Matter?

Abstract Objective To determine if the route of administration of whole blood cardioplegia (cardioplegia) is significantly associated with the frequency of profound transient hypotension (intermittent “vasoplegia”) often observed during cardioplegia..

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A Continuous, Real-Time Coagulation State Monitor for ECMO Patients

Abstract For patients undergoing extracorporeal membrane oxygenation (ECMO), clot formation is a critical complication requiring high-risk circuit changes. Blood tests used to assess clotting risk may be drawn only four..

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Red blood cell transfusion practices in extracorporeal membrane oxygenation: A single-center study

Abstract Objectives Evaluating blood transfusion practices and their impact on morbidity and mortality across extracorporeal membrane oxygenation (ECMO) configurations. Background As ECMO becomes increasingly utilised in critical care, the ideal..

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Arterial Cannula Size Selection for Percutaneous Femoral Venoarterial Extracorporeal Membrane Oxygenation in Children and Young Adults: Solving a Goldilocks Paradox?

Abstract The correct arterial cannula size for percutaneous femoral venoarterial extracorporeal membrane oxygenation (VA-ECMO) cannulation is imperative for adequate circulatory support. We aimed to describe the relationship between cannula size,..

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The Relationship Between the Type of Microorganisms Isolated in Cultures and Outcomes in Children on Extracorporeal Membrane Oxygenation Support Following…

Abstract Objetives Extracorporeal membrane oxygenation (ECMO) after surgery for congenital heart disease (CHD) provides hemodynamic support to patients when their myocardial function is temporarily affected. Postoperative infections in children with..

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Hematocrit and total protein elimination as quality control parameters of cell salvage

Abstract Background:   The use of cell salvage reduces homologous blood transfusions during operations and avoids associated complications. Therefore, autotransfusion is an integral part of Patient Blood Management (PBM). The..

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Investigation of contamination and environmental exposure of cold/heated water supply systems for extracorporeal circulation used in ECMO and other applications

Abstract Infection cases have been reported where Legionella spp. and NTM (non-tuberculous mycobacteria) increased due to the contamination of circulating water in cold/heated water supply systems for extracorporeal circulation used in cardiac..

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New Findings on Pulsatile ECMO: Verification of the Potential to Improve Antithrombogenicity of a Membrane Oxygenator Using Pump-Generated Pulsatile Flow…

Abstract Background Extracorporeal membrane oxygenation (ECMO) provides mechanical circulatory and respiratory support. However, thrombus formation in the circuit can lead to hemorrhagic complications, requiring improvements in ECMO anti-thrombogenicity. Few studies..

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Refractory anaphylactic shock to peanut ingestion in a pediatric patient requiring extracorporeal life support

Abstract Introduction Current guidelines advise that anaphylactic shock refractory to traditional treatments may be managed with extracorporeal life support (ECLS), but reports have been exclusive to adults. Case Report We..

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Comparative analysis of perioperative outcomes between hybrid system and MiECC: A prospective pilot study

Abstract Background: Minimally invasive extracorporeal circulation (MiECC) has been introduced to mitigate the inflammatory response and reduce blood transfusion needs compared to conventional cardiopulmonary bypass (CPB) perioperatively. A hybrid system..

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Successful Treatment of Extracorporeal Membrane Oxygenation Induced Digital Ischemia in Infants Using Botulinum Toxin Type A

Abstract Digital ischemia following extracorporeal membrane oxygenation (ECMO) therapy is a known complication with potential devastating long-term sequela. Onabotulinum toxin type A (BTX-A) has been demonstrated to be effective for..

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The Effect of Hypotension on Cerebral Metabolism and Perfusion in Adults Undergoing Cardiopulmonary Bypass: A Prospective Cohort Study

Abstract BACKGROUND:  Current blood pressure management strategies cannot accommodate large interindividual variations in cerebral autoregulation, which may result in inadvertent cerebral ischemia. A novel optical neuromonitoring device was developed to..

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CPR-induced consciousness in hypothermic cardiac arrest: Where is the limit of tolerance of the human brain? A case report

Abstract BackgroundCPR-induced consciousness (CPRIC) is defined as consciousness during CPR, ranging from eye opening to combative behaviour and vocalisation, despite the absence of spontaneous circulation. CPRIC has not previously been..

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Clinical evaluation of SafeCEC® one-way valve in hemolysis during CPB: Pilot study

Abstract Introduction: In cardiopulmonary bypass (CPB), blood circulation is temporarily maintained by an artificial blood-pumping device during cardiac surgery. Worldwide, approximately half of the CPB procedures utilize either centrifugal or..

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Minimally invasive, transapical dual-lumened cannula for short-term left ventricular support in a clinically relevant large animal model†

Abstract OBJECTIVES Cardiogenic shock is still a major clinical challenge, despite the available devices. We developed a minimally invasive, transapical dual-lumened cannula, which can provide antegrade circulatory support and unloading..

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The protective effect of pulmonary artery infusion with HTK solution on the lungs during prolonged cardiopulmonary bypass surgery

Abstract Background Studies have proved that artery infusion during CPB operations can reduce lung injury led by CPB surgery. This study was undertaken to investigate the effects of HTK solution..

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The 10 Commandments of On-Table Extubation After Cardiac Surgery: Why and How to Increase Adoption

Abstract Introduction It is around 4 PM when the surgeon, having just transferred his afternoon theater patient to the intensive care unit (ICU), approaches the patient’s family with a reassuring..

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On-Table Reanimation of a Pediatric Heart from Donation after Circulatory Death

Abstract Cardiac allotransplantation is warranted in children with end-stage heart failure or irreparable congenital heart disease. A dearth of organs for transplantation has contributed to long wait-list times and resultant..

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Assisted artificial intelligence in medical writing: a primer for humans

Abstract Assisted artificial intelligence (A-AI) has rapidly become a gold standard approach for conducting data analysis and medical writing []. From executing complex statistical tasks to extracting relevant information and..

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Technique of Intra-Aortic Balloon Pump Insertion Through Axillary Artery Over a Chimney Graft

Abstract Intra-aortic balloon pump (IABP), which augments coronary blood flow and reduces cardiac afterload, is the most widely used temporary mechanical circulatory support (TMCS) device. It has been used in..

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Is hyperoxia in early pediatric veno-veno extracorporeal life support associated with mortality?

Abstract Background: Data is limited regarding the effects of supraphysiologic blood oxygen tension (hyperoxia) in patients requiring extracorporeal life support (ECLS). We sought to evaluate the association between hyperoxia and..

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Time-dose response of oxygen delivery during cardiopulmonary bypass in mitral valve surgery: does surgical approach matter?

Abstract Introduction Increased time-dose-response (TDR) of suboptimal oxygen delivery (DO2) during cardiopulmonary bypass (CPB) has been associated with increased postoperative complications. The impact of surgical approach - minimally invasive vs...

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Randomized Trials in Cardiac Surgery: Why and How

Abstract OBJECTIVES Randomized clinical trials (RCTs) are the gold standard for comparative effectiveness. However, they face unique challenges in cardiac surgery. The objective of this work is to summarize the..

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Efficacy of hemadsorption combining with cardiopulmonary bypass used in patients with acute type A aortic dissection

Abstract Background It is hypothesized that combining HA380 with cardiopulmonary bypass (CPB) in acute type A aortic dissection (ATAAD) surgery could reduce the inflammatory response induced by CPB and subsequently..

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Unilateral Versus Bilateral Antegrade Cerebral Perfusion in Aortic Arch Surgery: Systematic Review and Meta-Analysis of Randomised Controlled Trials and Propensity-Matched…

Abstract Background Selective antegrade cerebral perfusion, via unilateral antegrade cerebral perfusion (uACP) or bilateral antegrade cerebral perfusion (bACP) approaches, is used in aortic arch surgery to protect the brain during..

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Work in Europe: schools and Board

We are getting a lot of questions about working in Europe as a Perfusionist. Each country has its own regulations, its perfusion qualification, but we always say that a great..

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Mitochondrial Dysfunction in Cardiac Surgery

Abstract The human heart has one of highest metabolic requirements in the body: even in a resting physiologic state it must work to circulate approximately 5 L/min to 8 L/min..

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Activated Clotting Time Measured by Hemochron Signature Elite in Adult Cardiac Surgery: Implications for Clinical Practice

Abstract Objectives To assess concordance between Hemochron Response (ACTr) and the three-activator device Hemochron Signature Elite (ACTe) in adult cardiac surgery patients. To evaluate the correlation between ACTe and anti-Xa..

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