Yearly Archives: 2025

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Vasoplegia in Cardiac Surgery: A Systematic Review and Meta-analysis of Current Definitions and Their Influence on Clinical Outcomes

Abstract Objectives To identify differences in the reported vasoplegia incidence, intensive care unit (ICU) length of stay (LOS), and 30-day mortality rates as influenced by different vasoplegia definitions used in..

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Fluid management in adult patients undergoing venoarterial extracorporeal membrane oxygenation: A scoping review

Abstract Background The use of venoarterial extracorporeal membrane oxygenation (VA-ECMO) as a cardiocirculatory support has tremendously increased in critically ill patients. Although fluid therapy is an essential component of the..

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Summary of the best evidence for the management of kinesiophobia in patients after cardiac surgery

Abstract Background This study aimed to systematically search for relevant evidence on the management of kinesiophobia in patients after cardiac surgery both home and abroad. The evidence was evaluated and..

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Carboxyhemoglobin and Methemoglobin as Biomarkers of Hemolysis and Mortality in Acute Respiratory Distress Syndrome Treated by Veno-Venous Extracorporeal Membrane Oxygenation

Abstract BACKGROUND:  Critically ill patients who receive circulatory or respiratory assist using extracorporeal membrane oxygenation (ECMO) may develop hemolysis, which can complicate the delivery of supportive care and be a..

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Aortic Regurgitation - Regurgitacion Aortica

      The echo lady; Lorena De Vanna, is a cardiac and respiratory physiologist graduated from the Central University of Venezuela. She currently holds British Society of Echocardiography accreditation..

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Preparing lung transplant with Ex Vivo Lung Perfusion Device

Preparing the Child lung for transplant into the Adult patient with usage of EVLPD or Ex Vivo Lung Perfusion Device a practical application which every Perfusionist should be familiar with...

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Totally Robotic Left Atrial Myxoma Removal

Totally Robotic Left Atrial Myxoma Removal with Ant.Lat Thoracotomy of the right chest limited accress femoral and Int.Jugular Cannula inserted for total inflow occlusion technique as well as cardio with..

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Lung procurement with ex vivo lung perfusion

A complete advance series of lung procurement and usage of ex vivo lung perfusion technologies or device either in the presence of pulmonary thromboembolism.   Dr.Sam Zeraatian Nejad Davani, CEO..

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Circular Shunt: A Loop Not to Be Ignored

Abstract A circular shunt, initially described by Shone et al. in 1962, refers to abnormal blood recirculation through complete intracardiac or intra- and extracardiac communications, bypassing the capillary beds. This..

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Left Ventricular Unloading Using Intra-aortic Entrainment Pumping Before Reperfusion Reduces Post-AMI Infarct Size

Abstract Background Anterior myocardial infarction standard of care prioritizes swift coronary reperfusion. Recent studies show left ventricular (LV) unloading with transvalvular axial flow pumps for 30 minutes before reperfusion (vs..

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Total bilirubin as a marker for hemolysis and outcome in patients with severe ARDS treated with veno-venous ECMO

Abstract Background Hemolysis is a common complication in critically ill patients with sepsis, acute respiratory distress syndrome (ARDS) or therapy with extracorporeal membrane oxygenation (ECMO). Heme degradation product bilirubin might..

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The impact of thyroid function on surgical prognosis in patients undergoing cardiac and major vascular surgeries

Abstract Objective This study aims to elucidate the relationship between thyroid function and surgical prognosis in patients undergoing cardiac and major vascular surgeries. Methods A retrospective cohort study was conducted..

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Prothrombotic Microvesicle Generation in Pediatric Cardiopulmonary Bypass: A Pilot Observational Study

Abstract Over 10% of children develop thrombosis after cardiac surgery for congenital heart disease. Children with a single ventricle physiology have the highest risk of thrombosis associated with increased length..

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Prevalence, Risk Factors, and Outcomes of Hospital-Acquired Infections in Children After Congenital Heart Surgery

Abstract Background Hospital-acquired infections (HAIs) are associated with morbidity and mortality in children following congenital cardiac surgery. Our center performs approximately 200 congenital surgeries a year, but infection rates and..

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Assay of cardiopulmonary bypass system for porcine alveolar macrophages removing GFP-E. coli from erythrocyte surfaces

Abstract While it is established that complement receptor molecules on the surface of erythrocytes are crucial for the clearance of immune complexes in the body, the molecular mechanisms underlying the..

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Awake veno-venous extracorporeal membrane oxygenation: practical aspects and considerations

Abstract Veno-venous extracorporeal membrane oxygenation (ECMO) is a life-saving technique in the armamentarium of critical care medicine. It involves extracorporeal blood circulation outside the body, providing temporary respiratory support while..

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Association of carboxyhemoglobin and methemoglobin levels with hemolysis during extracorporeal membrane oxygenation

Abstract Introduction: Hemolysis, characterized by increased carboxyhemoglobin (COHb) and methemoglobin (MetHb) levels, is a complication of extracorporeal membrane oxygenation (ECMO). Methods: This prospective single-center study aimed to investigate the correlation..

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Principles and Functions of Cardiopulmonary Bypass (CPB).

Cardiopulmonary Bypass (CPB) is one of the most critical advancements in cardiac surgery. It allows the surgical team to operate on a non-beating heart by temporarily taking over the functions..

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Abrupt left coronary artery malperfusion secondary to acute type A aortic dissection after weaning from cardiopulmonary bypass: a case report

Abstract Introduction Acute Stanford type A aortic dissection (ATAAD) is a lethal emergency. However, even with instant surgical repair, early mortality is up to 20%. ATAAD complicated by coronary artery..

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Comparison of Manual and Mechanical Ventilation During Intensive Care Unit Transport Following Cardiac Surgery: Impact on Oxygenation, Ventilation, and Hemodynamic…

Abstract Objectives Following cardiac surgery, patients often require ventilatory support during transport to the intensive care unit (ICU). Manual ventilation using a bag valve mask (BVM) is commonly employed; however,..

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A comprehensive organ protection strategy in total arch replacement: a propensity-weighted analysis

Abstract OBJECTIVES The goal was to report the outcomes and determine the effectiveness of a comprehensive organ protection strategy in total arch replacement. METHODS A total of 350 patients who..

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A Review of Emerging Evidence and Clinical Applications of Hyperbaric Oxygen Therapy

Abstract Background: Hyperbaric Oxygen Therapy (HBOT) is a medical treatment that involves administering 100% oxygen at increased atmospheric pressure to enhance oxygen delivery to tissues. Initially developed for decompression sickness, HBOT..

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Capillary refill time and tissue oxygen saturation as factors influencing lower limb ischemia in VA-ECMO: a case-control study

Abstract Background and objectives Venous-Arterial Extracorporeal Membrane Oxygenation (VA-ECMO) is a pivotal means for rapid cardiopulmonary support, yet it may result in lower limb ischemia. This study aims to explore..

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The Impact of Blood Pressure Below Personalized Lower Cerebral Autoregulation Limit on Outcomes After Cardiac Surgery: A Retrospective Study

Abstract Objective The clinical importance of individualized blood pressure management in optimizing cerebral perfusion during cardiac surgery has been well established. However, consensus on blood pressure goals is lacking. The..

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Early CABG with intraoperative hemoadsorption in patients on ticagrelor: Real world data from the international Safe and Timely Antithrombotic Removal…

Abstract Objectives Severe perioperative bleeding occurs in over 30 % of patients on ticagrelor undergoing isolated coronary artery bypass grafting (i-CABG) before completing the recommended 3-day washout. Intraoperative ticagrelor removal with..

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The Association Between Platelet Transfusion and Acute Kidney Injury Following Fontan Surgery

Abstract Objectives: Previous studies have demonstrated an association between transfusion and increased organ dysfunction. We sought to determine the association between transfusion of blood components (red blood cell [RBC], plasma, platelet,..

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Lactate: The Fallacy of Oversimplification

Abstract Almost a quarter of a millennium after the discovery of an acidic substance in sour milk by Swedish chemist Carl Wilhelm Scheele and more than 100 years after the..

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The Effect of Extracorporeal Membrane Oxygenation on the Pharmacokinetics of Dexmedetomidine Hydrochloride

Abstract Objectives Our objective was to explore the effects of extracorporeal membrane oxygenation (ECMO) on the pharmacokinetics of dexmedetomidine hydrochloride via vitro and in vivo experiments Design A single-center animal..

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