Monthly Archives: noviembre 2025

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Differential Hypoxemia During Veno-Arterial Extracorporeal Organ Support: Its Impact on Mortality and Different Treatment Strategies

Abstract Objectives Extracorporeal Life Support (ECLS) has evolved into an established treatment for severe cardiogenic shock. As most patients have residual antegrade left ventricular output toward the descending aorta that..

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Characteristics Associated with Mortality in 623 Patients Who Received Recombinant Factor VIIa for Bleeding in Cardiac Surgery

Abstract Objectives Activated recombinant factor VII (rFVIIa) has been used to treat cardiac surgical bleeding in an off-label manner. Due to the high risk of mortality with ongoing hemorrhage, assessing..

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Routine administration of enoximone in neonates and infants undergoing cardiac surgery with cardiopulmonary bypass to prevent and treat early low…

Abstract Low cardiac output syndrome (LCOS) is defined by an insufficient cardiac output to meet metabolic demands, leading to tissue hypoperfusion and potential organ dysfunction. Although it affects up to 42%..

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Dose-Dependent Changes in Clot Firmness in Thromboelastometry After Administration of Fibrinogen Concentrate: A Retrospective Observational Study

Abstract Introduction Viscoelastic point-of-care diagnostics are crucial in cardiac surgery. In the FIBTEM assay of rotational thromboelastometry (ROTEM), guidelines suggest target maximum clot firmness values to reduce perioperative bleeding. The..

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Advances and Challenges in Artificial Womb for Respiratory Support in Extremely Low Gestational Age Neonates: A Narrative Review

Abstract Background Respiratory management of extremely low gestational age neonates (ELGANs) is a major challenge in neonatal intensive care, as they face high mortality and morbidity due to complications such..

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Cerebral Hemodynamic Changes and Postoperative Brain Function in Patients Undergoing Cardiac Valve Surgery With Cardiopulmonary Bypass: A Prospective Cohort Study

Abstract Background Cardiopulmonary bypass (CPB) during cardiac surgery disrupts cerebral hemodynamics, potentially leading to postoperative neurological complications such as delirium. Transcranial Doppler (TCD) offers non-invasive monitoring of cerebral blood flow..

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Thrombus formation in neonates and early infants undergoing congenital heart surgery

Abstract Objective This study evaluated thrombus formation and its impact on outcomes in neonates and early infants undergoing congenital heart surgery. Methods Neonates and early infants (≤90 days) undergoing congenital..

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Comparison of post-operative inflammatory biomarkers between minimal invasive extracorporeal circulation and conventional extracorporeal circulation in cardiac surgery. A meta-analysis of…

Abstract Background/Aim Recent literature suggested that the use of Minimal Invasive Extracorporeal Circulation (MIECC) may mitigate the inflammatory response in patients undergoing cardiac surgery. We aimed to perform a meta-analysis..

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Towards goal-directed perfusion - Part II: Temperature dependence of Q10, oxygen-demand dependence on age and weight, further clinical insights

Abstract Background Goal-directed perfusion (GDP) during cardiopulmonary bypass (CPB) seeks to match oxygen delivery with patient-specific metabolic demand, yet determinants of oxygen demand and dynamics of oxygen extraction ratio (OER)..

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Congenital diaphragmatic hernia: Exclusion criteria for repair or ECMO?

Abstract Background Mortality in congenital diaphragmatic hernia (CDH) approximates 30 %. Both severe lung hypoplasia and other anomalies contribute to demise regardless of repair and/or extracorporeal membrane oxygenation (ECMO). We..

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Knowledge and behaviours of the operating room personnel regarding protection from ionising radiation

Abstract Introduction: Ensuring radiation safety in healthcare settings is crucial to minimising risks associated with ionising radiation exposure. This study aimed to evaluate the knowledge and behaviours of operating room..

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Clinical study of area-decreasing technique and conventional post-closure technique for V-A ECMO weaning application: study protocol of a randomised controlled…

Abstract Introduction Two techniques are commonly used for the femoral artery puncture closure during decannulation in venoarterial extracorporeal membrane oxygenation (V-A ECMO): the conventional post-closure technique and the small-sheath technique, also..

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Association between parenteral nutrition and extracorporeal membrane oxygenation circuit dysfunction in critically ill adults requiring extracorporeal life support: A retrospective…

Abstract Background Extracorporeal life support is influenced by membrane integrity and nutrition. The impact of parenteral nutrition with lipid injectable emulsions on membrane function remains uncertain. Methods This retrospective cohort..

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Effect of Perioperative Dexmedetomidine in Cardiac Surgery: A Narrative Review

Abstract Cardiac procedures carry a higher perioperative risk than other operations for major adverse cardiovascular events and kidney injury, especially since patients with multiple comorbidities have been accepted as candidates..

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ISHLT Consensus Statement on the Perioperative use of ECLS in Lung Transplantation: Part I: Preoperative Considerations

Abstract The use of extracorporeal life support (ECLS) throughout the perioperative phase of lung transplantation requires nuanced planning and execution by an integrated team of multidisciplinary experts. To date, no..

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The TEG6s-Derived R ratio accurately reflects the anti-Xa level after cardiac surgery: A proof-of-concept study

Abstract Introduction In the postoperative intensive care setting after cardiac surgery with cardiopulmonary bypass (CPB), particularly in patients requiring continued anticoagulation for prosthetic devices such as mechanical valves or extracorporeal..

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Safely combining renal replacement therapy and extracorporeal membrane oxygenation

Abstract Extracorporeal membrane oxygenation (ECMO) is an extracorporeal technique used in acute circulatory and respiratory failures refractory to conventional therapies. ECMO patients are at risk of developing severe acute kidney..

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THE PITIE ECMO DIPLOMA - New dates 2026

GENERAL INFORMATION     Language will be English. Intensive teaching program: 1 week (total fo over 50 hours). The program will be interactive, with lectures, case studies and a lot of time devoted..

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2025 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care

Abstract In these guidelines, the American Heart Association provides updated guidance for resuscitation of adults and children in cardiac arrest or with a life-threatening condition due to special circumstances, including..

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Risk Models for Monitoring Postoperative Complication Rates After Paediatric Cardiac Surgery

Abstract Objectives As postoperative mortality for paediatric cardiac surgery is very low, we aimed to develop methods for monitoring of postoperative complication rates, given their impact upon children’s health and..

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Impact of changes in cardiopulmonary bypass circuit design on pressure loss, wall shear stress, and venous drainage flow

Abstract Introduction Blood damage during cardiopulmonary bypass can trigger postoperative inflammatory responses and organ injury. Therefore, optimizing the blood circuit design to minimize damage remains essential. However, variations in venous..

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Current State of Patient Blood Management in Cardiovascular Surgery: Insights from a Survey of Leading Centers

Abstract Objective To determine the state of patient blood management (PBM) practice in leading US cardiac surgery centers. Design A survey tool addressing PBM program structure and PBM program operations..

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Aerosolization of Mycobacterium chelonae from heater-cooler-devices: a continuing risk of exposure during cardiac surgery

Abstract Background Following identification of widespread Mycobacterium chimaera infections in 2013 associated with aerosolization from Sorin heater-cooler-devices (HCD), microbiological monitoring of HCDs has become mandatory in Switzerland. Methods Since 01/2016, four Maquet..

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Early Haptoglobin Decrease During a Microaxial Flow Pump Support: Association With High Pump Performance Level

Abstract Hemolysis is a recognized complication of a microaxial flow pump (Impella CP) support, but its incidence and associated risk factors remain unclear. We retrospectively analyzed 24 patients with cardiogenic..

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Patient blood management for patients undergoing cardiac surgery in Middle Eastern countries: Multicenter survey

Abstract Background:  The purpose of this survey was to delineate and compare patient blood management (PBM) approaches in cardiac surgery across nine Middle Eastern countries while identifying the main challenges..

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Entropy-guided sevoflurane administration during cardiopulmonary bypass surgery in the paediatric population

Abstract Background Maintaining optimal anesthetic depth during cardiopulmonary bypass (CPB) in pediatric patients is challenging due to altered physiology and unreliable conventional monitoring. Entropy, a processed electroencephalogram metric, offers a..

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Mobile ECMO for inter-hospital transport of pediatric patients: experience from 22 cases

Abstract Objective To summarize the management experience of inter-hospital transport of critically ill children with extracorporeal membrane oxygenation (ECMO) in our hospital and provide evidence for the mobile ECMO for..

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Practice of Apnea Testing and Determination of Brain Death During Extracorporeal Membrane Oxygenation: A Multicenter Retrospective Analysis

Abstract To explore whether reducing airflow and maintaining blood flow can improve the success rate of the apnea test (AT) and whether two auxiliary test strategies can improve the completion..

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Between Air and Artery: A History of Cardiopulmonary Bypass and the Rise of Modern Cardiac Surgery

Abstract Cardiopulmonary bypass (CPB) is one of the most groundbreaking medical innovations in history, enabling safe and effective heart surgery by temporarily replacing the function of the heart and lungs...

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Outcomes of central versus peripheral arterial cannulation for intraoperative extracorporeal membrane oxygenation support in lung transplantation

Abstract Background Intraoperative venoarterial extracorporeal membrane oxygenation (VA ECMO) is becoming the most common mode of extracorporeal life support (ECLS) in lung transplantation (LTx). We compared rates of primary graft..

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