Archivos mensuales: julio2025

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Unsupervised machine learning to explore inflammation following cardiopulmonary bypass

Abstract Introduction Cardiac surgery with cardiopulmonary bypass (CPB) often induces systemic inflammatory reaction syndrome (SIRS), affecting postoperative outcome. We aimed to explore adaptive/maladaptive inflammation using unsupervised machine learning. Methods We..

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Survival After Amniotic Fluid Embolism and Extracorporeal Membrane Oxygenation Support

Abstract Background Amniotic fluid embolism is a rare potential complication in the peripartum period. Case Summary A 27-year-old nulliparous woman presented for elective induction at 41 weeks' gestation. Due to..

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The dynamic interplay between endothelial reactivity, temperature, and vascular resistance in cardiopulmonary bypass

Abstract Cardiopulmonary bypass serves as a cornerstone in cardiac surgery, enabling life-sustaining circulatory and respiratory support during complex procedures that necessitate the temporary cessation of cardiac activity. This intricate process..

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“When I walk away and wonder, did I make the best decision?”: A decisional needs assessment among providers involved in…

Abstract Purpose Extracorporeal cardiopulmonary resuscitation (ECPR) is an advanced resuscitation therapy for cardiopulmonary arrest refractory to standard CPR. ECPR treatment recommendations are not supported by strong evidence, and institutional criteria..

Lee mas
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The Effects of Preoperative Resting Blood Pressure and Nighttime Blood Pressure on the Associations between Perioperative Blood Pressures and Postoperative…

Abstract Objectives To describe the associations between perioperative blood pressures and clinical postoperative outcomes, and to investigate if these associations depend on the preoperative resting and nadir nighttime blood pressures...

Lee mas
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Prone positioning and bleeding risk during extracorporeal membrane oxygenation in severe ARDS patients

Abstract Purpose To assess whether prone positioning (PP) increases bleeding risk compared to supine positioning in ARDS patients undergoing veno venous Extracorporeal Membrane Oxygenation (VV ECMO). Materials and Methods A..

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The role of acute normovolemic hemodilution and retrograde autologous priming in reducing intraoperative packed red blood cell transfusion needs in…

Abstract Background Acute normovolemic hemodilution (ANH) and retrograde autologous priming (RAP) are blood conservation techniques designed to reduce transfusion requirements. Purpose This study evaluated the impact of combining ANH and..

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Removal of EpCAM-positive tumor cells during intraoperative blood salvage– A pivotal multicenter clinical study (REMOVE)

Abstract Background Intraoperative blood salvage can reduce the need for allogeneic blood transfusions, minimizing immunological risks and infection by reusing the patient's own blood. However, in cancer surgery, a key..

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Hyperoxia and acute brain injury

Abstract We read the interesting work of Romero‑Garcia and colleagues on the association between partial pressure of O2 in arterial blood (PaO2) and neurological outcomes in a context of acute brain..

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Incidence, Risk Factors, and Outcomes of Seizures in Extracorporeal Cardiopulmonary Resuscitation Patients: An Analysis of the Extracorporeal Life Support Organization…

Abstract Extracorporeal cardiopulmonary resuscitation (ECPR) for refractory cardiac arrest is increasing in usage, but risk factors for seizures are largely unknown. We included adult ECPR patients in the Extracorporeal Life..

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Inflammatory Markers During Extracorporeal Membrane Oxygenation in Neonates With Congenital Diaphragmatic Hernia

Abstract This study aimed to assess whether the proinflammatory markers procalcitonin (PCT), C-reactive protein (CRP), or interleukin 6 (IL-6) are associated with mortality in neonates with congenital diaphragmatic hernia (CDH)..

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Investigating optimal drainage cannula for venovenous extracorporeal membrane oxygenation: impact of side holes on blood oxygenation – an in vitro…

Abstract Venovenous extracorporeal membrane oxygenation (VV ECMO) relies on effective blood drainage, and cannula design plays a crucial role in optimizing blood oxygenation. Recirculation, where oxygenated blood returns to the..

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A Miniaturized Centrifugal Pump ECMO System Enhances Hemocompatibility in Small Animal Models

Abstract Extracorporeal membrane oxygenation (ECMO) is a fundamental treatment for cardiovascular and severe pulmonary diseases, with small animal models providing critical insights into organ protection during cardiopulmonary bypass and ECMO..

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The impact of antithrombin III supplementation on prognosis during extracorporeal membrane oxygenation: a systematic review and meta-analysis

Abstract Extracorporeal membrane oxygenation (ECMO) is a mechanical circulatory and respiratory support system that facilitates gas exchange and hemodynamic stabilization through an external circuit. ECMO has been increasingly utilized for..

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Extracorporeal Membrane Oxygenation in Pregnancy: An Analysis of the Extracorporeal Life Support Organization Registry

Abstract Objectives:  We examined data from the International Registry of the Extracorporeal Life Support Organization to identify risk factors for mortality in pregnant and peripartum patients receiving extracorporeal membrane oxygenation...

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An intraoperative nightmare: sudden bilateral lower limb malperfusion during type A acute aortic dissection surgery

Abstract Lower limb malperfusion for type A acute aortic dissection (ATAAD) is a challenging complication, particularly when it occurs suddenly during the operation. We report a 76‐year‐old female with ATAAD..

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Dynamic and interpretable deep learning model for predicting respiratory failure following cardiac surgery

Abstract Background Postoperative respiratory failure following cardiac surgery (CS-PRF) remains a critical complication with substantial morbidity and mortality. Current risk prediction models are limited by static assessments and suboptimal accuracy...

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Delayed neurological recovery in patients after extracorporeal resuscitation compared to conventional resuscitation. Implications for outcome assessment after cardiac arrest

Abstract Introduction Extracorporeal cardiopulmonary resuscitation (eCPR) is a rescue therapy for refractory cardiac arrest, with evidence suggesting improved outcomes when performed at experienced centres. Unlike conventional CPR (cCPR), eCPR patients..

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Re-evaluating the impact of mechanical ventilation strategies during cardiac surgery with cardiopulmonary bypass: work in progress

Abstract Cardiac surgery is a commonly performed procedure worldwide, with an estimated 1–1.5 million cases per year and figures destined to increase in the next few years []. A significant..

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Blood perfusion through ventricular assist devices induces erythrocytes to interact with leukocytes

Abstract Implantations of  (VADs) have significantly improved  and life expectancy of end-stage heart failure patients. However, despite the advancements in the VAD designs and patient management protocols, the VAD recipients remain at..

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Do Sex Differences Matter in Cardiac Surgery-Associated Acute Kidney Injury? – A Narrative Review

Abstract Cardiac surgery-associated acute kidney injury (CSA-AKI) is a common complication following cardiac surgery. Despite growing awareness of sexual dimorphism in cardiovascular and chronic kidney disease, little is known about..

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Impact of Venoarterial Extracorporeal Membrane Oxygenation on Hemodynamics and Cardiac Mechanics: Insights From Pressure-Volume Loop Analysis

Abstract Venoarterial extracorporeal membrane oxygenation (VA-ECMO) serves as a critical mechanical circulatory support modality, sustaining systemic circulation in cases of severe cardiac failure or cardiac arrest. While VA-ECMO improves hemodynamics,..

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Knowledge domains and hotspots in corticosteroid use for cardiac surgery: a 23-Year bibliometric and visualized analysis

Abstract Background The safety and efficacy of prophylactic corticosteroid administration during the perioperative period of cardiac surgery have undergone extensive and comprehensive examination. In this study, we conducted a bibliometric..

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The intra-aortic balloon pump: a modern practical perspective

Abstract Purpose of review  After more than 50 years from its invention, the intra-aortic balloon pump (IABP) is still one of the most widely used mechanical circulatory support devices to..

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Everolimus and Low-Dose Tacrolimus After Heart Transplant in Children

Abstract Importance  Studies suggest that everolimus may reduce the risk of rejection, cardiac allograft vasculopathy (CAV), chronic kidney disease (CKD), and cytomegalovirus (CMV) after heart transplant. Everolimus use is controversial because..

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Nutritional support in pediatric patients with extracorporeal membrane oxygenation: new insights

Abstract Nutritional support in pediatric patients receiving extracorporeal membrane oxygenation (ECMO) therapy is controversial. Although ECMO is increasingly used in pediatric intensive care units, there is no consensus on the..

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Intraoperative hypotension prediction in cardiac and noncardiac procedures: is HPI truly worthwhile? A systematic review and meta-analysis

Abstract Background Intraoperative hypotension (IOH), defined as a mean arterial pressure (MAP) below 65 mmHg, is a common complication during surgery and is associated with significant postoperative morbidity, including acute..

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Is it Time to Upgrade Neuromonitoring in ECPR Recipients to Evaluate Cerebral Perfusion Imbalances Adequately?

Abstract Veno-arterial extracorporeal membrane oxygenation (ECMO) brings many monitoring pitfalls due to the countercurrent blood flow, which may create left ventricular overload and perfusion imbalances between the two cerebral hemispheres...

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Exploring the Association Between Early PaCO2 Correction Speed and Cerebrovascular Autoregulation in a Porcine Model of Extracorporeal Resuscitation

Abstract Background Prior clinical research demonstrated that rapid reduction in arterial carbon dioxide (PaCO2) levels during extracorporeal membrane oxygenation (ECMO) is associated with acute brain injury (ABI), which may be..

Lee mas
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Relationship between intraoperative blood pressure variability and postoperative acute kidney injury in pediatric cardiac surgery

Abstract Background Cardiac surgery-associated acute kidney injury (CSA-AKI) is a notably common complication in pediatrics, with an incidence rate ranging from 15 to 64%. This rate is significantly higher than..

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