Yearly Archives: 2024

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Polymerized Human Hemoglobin–Based Oxygen Carrier Preserves Lung Allograft Function During Normothermic Ex Vivo Lung Perfusion

Abstract Normothermic ex vivo lung perfusion (EVLP) can resuscitate marginal lung allografts to increase organs available for transplantation. During normothermic perfusion, cellular metabolism is more active compared with subnormothermic perfusion, creating a..

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Effects of albumin and crystalloid priming strategies on red blood cell transfusions in on-pump cardiac surgery: a network meta-analysis

Abstract Background In on-pump cardiac surgery, the albumin priming strategy could maintain colloid osmotic pressure better than crystalloid solutions and reduce excessive perioperative fluid balance. However, a high-quality meta-analysis is..

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Predicting long-term time to cardiovascular incidents using myocardial perfusion imaging and deep convolutional neural networks

Abstract Myocardial perfusion imaging (MPI) is a clinical tool which can assess the heart's perfusion status, thereby revealing impairments in patients' cardiac function. Within the MPI modality, the acquired three-dimensional..

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Agreement of pCO2 in venous to arterial blood gas conversion models in undifferentiated emergency patients

Abstract Background Venous blood gas sampling has replaced arterial sampling in many critically ill patients, though interpretation of venous pCO2 still remains a challenge. Lemoël et al., Farkas and Zeserson et..

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Effect of intranasal insulin administration on postoperative delirium prevention in elderly cardiac surgery patients: study protocol for a multicenter, double-blind,…

Abstract Background Postoperative delirium (POD) is a complication after surgery which leads to worse outcomes. The frequency of this syndrome is increasing as more elderly patients undergo major surgery. The..

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Post-Operative Delirium and Cognitive Dysfunction in Aged Patients Undergoing Cardiac Surgery: A Randomized Comparison between Two Blood Oxygenators

Abstract In elderly patients undergoing cardiac surgery, extracorporeal circulation affects the incidence of post-operative delirium and cognitive impairment with an impact on quality of life and mortality. In this study,..

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Intraoperative circulatory arrest secondary to high-risk pulmonary embolism. Case series and updated literature review

Abstract Background Intraoperative pulmonary embolism (PE) with cardiac arrest (CA) represents a critical and potentially fatal condition. Available treatments include systemic thrombolysis, catheter-based thrombus fragmentation or aspiration, and surgical embolectomy...

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Simulated cardiopulmonary bypass: a high fidelity model for developing and accessing clinical perfusion skills

Abstract Background Traditionally, novice perfusionists learn and practice clinical skills, during live surgical procedures. The profession’s accrediting body is directing schools to implement simulated cardiopulmonary bypass (CPB) into the curriculum...

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Cardiopulmonary Bypass Circuit Obstruction and Urgent Replacement After the Administration of Andexanet Alfa

Abstract Thrombus occlusion in the cardiopulmonary bypass (CPB) circuit is a life-threatening adverse event. Herein, the authors present a case of Stanford type A aortic dissection in which the CPB..

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Hemolysis Precedes Urine Color Change in Patients Undergoing Open-Heart Surgery on Cardiopulmonary Bypass

Abstract Purpose: Red-colored urine often occurs in patients in the perioperative period who undergo cardiac surgery using cardiopulmonary bypass (CPB). This urine color change has been utilized for approximating hemolysis..

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Preoperative continuation of aspirin before isolated heart valve surgery and postoperative bleeding and transfusion: a single-center retrospective study

Abstract Background The risks and benefits of preoperative aspirin continuation in patients undergoing isolated heart valve replacement surgery are unclear. We investigated the effect of aspirin continuation on the risk..

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Randomized controlled trial of remote ischemic preconditioning in children having cardiac surgery

Abstract Background Children undergoing cardiac surgery are at risk for acute kidney injury (AKI) and cardiac dysfunction. Opportunity exists in protecting end organ function with remote ischemic preconditioning. We hypothesize..

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Mechanical Ventilation During Cardiopulmonary Bypass

Con: Mechanical Ventilation During Cardiopulmonary Bypass Abstract The ventilatory strategy to adopt during cardiopulmonary bypass is still being debated. The rationale for using continuous positive airway pressure or mechanical ventilation..

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Capillary refill time assessment after fluid challenge in patients on venoarterial extracorporeal membrane oxygenation: A retrospective study

Abstract Background Monitoring fluid therapy is challenging in patients assisted with Veno-arterial ECMO. The aim of our study was to evaluate the usefulness of capillary refill time to assess the..

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Extracorporeal Membrane Oxygenation Ouroboros: A Rare Cause of Mass Recirculation During Femoro-Jugular Venovenous ECMO

Abstract A 53 year old female was referred to our quaternary center for venovenous extracorporeal membrane oxygenation (ECMO) retrieval. Following a brief admission for a cosmetic procedure, she had represented..

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Pao2 and Mortality in Neonatal Extracorporeal Membrane Oxygenation: Retrospective Analysis of the Extracorporeal Life Support Organization Registry, 2015–2020

Abstract Objectives:  Extracorporeal life support can lead to rapid reversal of hypoxemia but the benefits and harms of different oxygenation targets in severely ill patients are unclear. Our primary objective..

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Antibiotic Prophylaxis in Patients On Extracorporeal Membrane Oxygenation: A Systematic Review

Abstract Despite the frequent use of prophylactic antibiotics in hospitals for extracorporeal membrane oxygenation (ECMO) patients, the Extracorporeal Life Support Organization (ELSO) Infectious Disease Task Force does not recommend routine..

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HeartMate 3 implantation with an emphasis on the biventricular configuration

Abstract Objectives Right ventricular failure following implantation of a durable left ventricular assist device (LVAD) is a major driver of mortality. Reported survival following biventricular (BiVAD) or total artificial heart..

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Successful heart transplant after 12 h preservation aboard a commercial flight

Abstract For the first time, a heart transplant has been successfully performed after transport of a donor heart across the Atlantic Ocean, marking a substantial advancement in the realm of..

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Top Three Considerations When Establishing An ECMO Program

Abstract Extracorporeal Membrane Oxygenation (ECMO) has emerged as a vital therapy offering a lifeline to critically ill patients with severe respiratory or cardiac failure. Its life-saving potential is undeniable, with survival..

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Venovenous Extracorporeal Membrane Oxygenation Candidacy Decision-Making

Abstract Background Use of venovenous extracorporeal membrane oxygenation (ECMO) is increasing, but candidacy selection processes are variable and subject to bias. Research Question What are the reasons behind venovenous ECMO..

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Extracorporeal Membrane Oxygenation (ECMO) Use as Supportive Therapy in a Patient With Acute Respiratory Distress Syndrome Due to Rupture of…

Abstract Pulmonary echinococcosis is a parasitic infection that accounts for 20% of the infected cases with echinococcosis. Patients may present after a cyst rupture associated with a variety of complications,..

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Unmasking the Impact of Oxygenator Induced Hypocapnia on Blood Lactate in Veno-Arterial Extracorporeal Membrane Oxygenation

Abstract Extracorporeal membrane oxygenation (ECMO) is often associated with disturbances in acid/base status that can be triggered by the underlying pathology or the ECMO circuit itself. Extracorporeal membrane oxygenation is..

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Improving ECMO therapy: Monitoring oxygenator functionality and identifying key indicators, factors, and considerations for changeout

Abstract Introduction: The optimal timing for extracorporeal membrane oxygenation (ECMO) circuit change-out is crucial for the successful management of patients with severe cardiopulmonary failure. This comprehensive review examines the various..

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Epidemiologic trends, risk factors and outcomes for pediatric myocarditis in the COVID era

Abstract Background During the peak of the COVID pandemic, there was a high degree of awareness around myocarditis as a potential manifestation. However, it is not very clear if hospitalizations..

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Percutaneous Venopulmonary Extracorporeal Membrane Oxygenation as Bridge to Lung Transplantation

Abstract Mechanical circulatory support (MCS) as a bridge to lung transplant is an infrequent but accepted pathway in patients who have refractory end-stage pulmonary failure. The American Association of Thoracic..

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Incorporating intraoperative blood pressure time-series variables to assist in prediction of acute kidney injury after type a acute aortic dissection…

Abstract Background: Acute kidney injury (AKI) is a common and serious complication after the repair of Type A acute aortic dissection (TA-AAD). However, previous models have failed to account for the..

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Microcirculatory Alterations in Cardiac Surgery: A Comprehensive Guide

Abstract Microcirculation is essential for cellular life and its functions. It comprises a complex network of capillaries, arterioles, and venules, which distributes oxygenated blood across and within organs based on..

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Urinary Collectrin as Promising Biomarker for Acute Kidney Injury in Patients Undergoing Cardiac Surgery

Abstract Background: Early detection of acute kidney injury (AKI) is crucial for timely intervention and improved patient outcomes after cardiac surgery. This study aimed to evaluate the potential of urinary..

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Risk of fluid accumulation after cardiac surgery

Abstract Objective Patients undergoing heart surgery are at high risk of postoperative fluid accumulation due to long procedures and cardiopulmonary bypass. In the present study, we sought to investigate the..

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