Yearly Archives: 2024

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Open-Source Image-Based Tool to Experimentally Evaluate Blood Residence Time in Clinical Devices

Abstract This article introduces an open-source tool to experimentally compare blood residence time in biomedical devices using an image-based method. The experimental setup and the postprocessing workflow are comprehensively elucidated..

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Perfusion During Aortic Arch Surgery—Keep it Physiologic!

Abstract We read with great interest the case presentation by Kaskar et al in the current issue of the World Journal for Pediatric and Congenital Heart Surgery. The authors describe two cases..

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The correlation of non-invasive hemoglobin testing and lab hemoglobin in surgical patients: A systematic review and meta-analysis

Abstract Background The decision regarding intraoperative transfusion has traditionally been based on hemodynamic instability and estimated blood loss. We performed a systematic review to determine the validity of the oximetry..

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Clinical Outcomes, Blood Utilization, and Ethical Considerations for Pediatric Patients in a Bloodless Medicine and Surgery Program

Abstract BACKGROUND: Pediatric patients requesting bloodless care represent a challenging clinical situation, as parents cannot legally refuse lifesaving or optimal interventions for their children. Here, we report clinical outcomes for..

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Initial experience and outcomes with a hybrid extracorporeal membrane oxygenation and cardiopulmonary bypass circuit for lung transplantation

Abstract Background The utilization of extracorporeal life support (ECLS) for intraoperative support during lung transplantation has increased over the past decade. Although veno-arterial extracorporeal membrane oxygenation (VA-ECMO) has recently emerged..

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Cardiac surgery elicits pericardial inflammatory responses that are distinct compared with postcardiopulmonary bypass systemic inflammation

Abstract Objectives Cardiac surgery using cardiopulmonary bypass contributes to a robust systemic inflammatory process. Local intrapericardial postsurgical inflammation is believed to trigger important clinical implications, such as postoperative atrial fibrillation..

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Finding a common definition of heparin resistance in adult cardiac surgery: communication from the ISTH SSC subcommittee on perioperative and…

Abstract Ensuring adequate anticoagulation for patients requiring cardiac surgery and cardiopulmonary bypass (CPB) is important due to the adverse consequences of inadequate anticoagulation with respect to bleeding and thrombosis. When..

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Effect of Glutamine Administration After Cardiac Surgery on Kidney Damage in Patients at High Risk for Acute Kidney Injury: A…

Abstract BACKGROUND: Acute kidney injury (AKI) is a common complication after cardiac surgery and is associated with increased morbidity and mortality. However, no specific treatment options are available, emphasizing the..

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The effects of pulsatile versus nonpulsatile flow on cerebral pulsatility index, mean flow velocity at the middle cerebral artery, regional…

Abstract Objective The objective of this retrospective review was to evaluate whether or not pulsatile flow improves cerebral hemodynamics and clinical outcomes in pediatric congenital cardiac surgery patients. Methods This..

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Creatinine Reduction Ratio Is a Prognostic Factor for Acute Kidney Injury following Cardiac Surgery with Cardiopulmonary Bypass: A Single-Center Retrospective…

Abstract Acute kidney injury (AKI) after cardiac surgery is a common complication that can lead to death. We previously reported that the creatinine reduction ratio (CRR) serves as a useful..

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Electroencephalography as a tool to predict cerebral oxygen metabolism during deep-hypothermic circulatory arrest in neonates with critical congenital heart disease

Abstract Objectives Recent research suggests that increased cerebral oxygen use during surgical intervention for neonates with congenital heart disease may play a role in the development of postoperative white matter..

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Blood flow and emboli transport patterns during venoarterial extracorporeal membrane oxygenation: A computational fluid dynamics study

Abstract Problem Despite advances in Venoarterial Extracorporeal Membrane Oxygenation (VA-ECMO), a significant mortality rate persists due to complications. The non-physiological blood flow dynamics of VA-ECMO may lead to neurological complications..

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Thrombotic Microangiopathic Anemia After Cardiac Surgery

Abstract THROMBOTIC MICROANGIOPATHIES (TMAs) are characterized by intravascular platelet activation, hemolysis, and microvascular thrombosis, causing multiorgan dysfunction. Precipitants include genetic predispositions, acquired immune dysregulation, infection, trauma, medications, organ transplantation, and..

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Efficacy of electroacupuncture on myocardial protection and postoperative rehabilitation in patients undergoing cardiac surgery with cardiopulmonary bypass: a systematic review…

Abstract OBJECTIVE: To evaluate the efficacy of electroacupuncture (EA) intervention on myocardial protection and postoperative rehabilitation in patients undergoing cardiac surgery with cardiopulmonary bypass (CPB). METHODS: Eight databases, including PubMed,..

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Venoarterial Extracorporeal Membrane Oxygenation Implementation in Septic Shock Rat Model

Abstract Septic shock, a global health concern, boasts high mortality rates. Research exploring the efficacy of venoarterial extracorporeal membrane oxygenation (VA-ECMO) in septic shock remains limited. Our study aimed to..

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Factors Influencing Unfractionated Heparin Pharmacokinetics and Pharmacodynamics During a Cardiopulmonary Bypass

Abstract Background Unfractionated heparin (UFH) is commonly used during cardiac surgery with a cardiopulmonary bypass to prevent blood clotting. However, empirical administration of UFH leads to variable responses. Pharmacokinetic and..

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After ECMO Decannulation, Are Patients Thriving or Just Surviving?

Abstract The use of extracorporeal membrane oxygenation (ECMO) to support patients with cardiac arrest, cardiogenic shock, and acute respiratory distress syndrome is rising worldwide.1 While ECMO may save the lives of..

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Volume Displacement Pulsatile Veno-Arterial Extracorporeal Membrane Oxygenation: Preliminary Data From In Vitro Tests

Abstract Veno-arterial extracorporeal membrane oxygenation (V-A ECMO) is increasingly used to treat refractory cardiogenic shock, despite randomized clinical trials reporting no difference in outcomes., Although traditional ECMO pumps maintain a constant flow..

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What’s new in VA-ECMO for acute myocardial infarction-related cardiogenic shock

Abstract Cardiogenic shock (CS) is a critical clinical syndrome  characterized by inadequate tissue perfusion and oxygen  delivery resulting from severe heart dysfunction, leading  to multi-organ failure. Diagnostic criteria include hypoperfusion..

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European practices on antithrombotic management during percutaneous mechanical circulatory support in adults: A survey of the Association for Acute CardioVascular…

Abstract Background Bleeding and thrombotic complications compromise outcomes in patients undergoing percutaneous mechanical circulatory support (pMCS) with veno-arterial extracorporeal membrane oxygenation (V-A ECMO) and/or microaxial flow pumps like the Impella™...

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Heart Transplantation From DCD Donors in Australia: Lessons Learned From the First 74 Cases

Abstract Heart transplantation from donation after circulatory death (DCD) donors has the potential to substantially increase overall heart transplant activity. The aim of this report is to review the first..

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Infection in Patients with ECLS

Infection in Patients with ECLS: next Euro ELSO webinar moderated by Peter Schellongowski Jordi Riera Marta Hernandez-Meneses Stephanie Thomas    

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Lactate and lactate clearance as predictors of one-year survival in extracorporeal cardiopulmonary resuscitation – An international, multicentre cohort study

Abstract Aim Extracorporeal cardiopulmonary resuscitation (ECPR) can be considered in selected patients with refractory cardiac arrest. Given the risk of patient futility and high resource utilisation, identifying ECPR candidates, who..

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Mechanical ventilation settings during weaning from venovenous extracorporeal membrane oxygenation

Abstract Objectives: To describe clinical characteristics, mechanical ventilation strategies, and outcomes in patients with severe acute respiratory distress syndrome (ARDS) during weaning from venovenous extracorporeal membrane oxygenation (VV ECMO). Design: Retrospective, multicenter cohort..

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Physiologic Effects of ECMO in Patients with Severe Acute Respiratory Distress Syndrome

Abstract Rationale: Blood flow rate affects mixed venous oxygenation (SvO2) during venovenous extracorporeal membrane oxygenation (ECMO), with possible effects on the pulmonary circulation and the right heart function. Objectives: We..

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Ethics in ECMO

Ethics in ECMO Moderators: Jonathan Smith, Francisco Abecasis Ethics in ECMO - the clinicians challenges Michael Broomé Ethics in ECMO - what literature has argued Alexandra Schou Ethics in ECMO..

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Determining ECMO Candidacy in the Age of Few Contraindications

Joint Webinar EuroELSO/ESPNIC - Determining ECMO Candidacy in the Age of Few Contraindications: A Panel Discussion 25 March 2024 Organizers: Dr. Elise Zivick (Chair) & Dr. Katie Doane for the..

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An architecturally rational hemostat for rapid stopping of massive bleeding on anticoagulation therapy

Abstract Hemostatic devices are critical for managing emergent severe bleeding. With the increased use of anticoagulant therapy, there is a need for next-generation hemostats. We rationalized that a hemostat with..

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Direct and continuous dosing of propofol can saturate Ex vivo ECMO circuit to improve propofol recovery

Abstract Background: Extracorporeal membrane oxygenation (ECMO) is a cardiopulmonary bypass device that provides life-saving complete respiratory and cardiac support in patients with cardiorespiratory failure. The majority of drugs prescribed to..

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Unresponsive Low Mixed Venous Oxygen Saturation During Early Intensive Care Unit Stay is Associated With Increased Risk of Organ Dysfunction…

Abstract Objectives The aim of the study was to determine if unresponsive mixed venous  (SvO2) values during early postoperative hours are associated with postoperative organ dysfunction. Design A single-center retrospective observational..

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