Yearly Archives: 2024

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Impact of hyperoxia on the gut during critical illnesses

Abstract Molecular oxygen is typically delivered to patients via oxygen inhalation or extracorporeal membrane oxygenation (ECMO), potentially resulting in systemic hyperoxia from liberal oxygen inhalation or localized hyperoxia in the..

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Perioperative acetaminophen is associated with reduced acute kidney injury after cardiac surgery

Abstract Background Cardiac surgery–associated  (AKI) is associated with increased postoperative morbidity and mortality. Evidence suggests an association between perioperative  administration and decreased incidence of postoperative AKI in  cardiac surgery patients; however, an effect..

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Respiratory extracorporeal membrane oxygenation

Abstract Background The use of extracorporeal membrane oxygenation (ECMO) for patients with acute respiratory distress syndrome (ARDS) has increased substantially. With modern trials supporting its efficacy, ECMO has become an..

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The Influence of High-Dose Parenteral Vitamin C on the Incidence and Severity of Postoperative Pulmonary Complications in Cardiac Surgery with…

Abstract Cardiac surgery (CS) with extracorporeal circulation (ECC), induces intense oxidative stress (OS) and systemic inflammatory response (SIR), which may seriously affect postoperative lung function. We aimed to test if..

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What the pediatric nurse needs to know about the Impella cardiac assist device

Abstract Background: Cardiogenic shock in children still carries a high mortality risk despite advances in medical therapy. The use of temporary mechanical circulatory supports is an accepted strategy to bridge patients..

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The approach to extracorporeal cardiopulmonary resuscitation (ECPR) in children. A narrative review by the paediatric ECPR working group of EuroELSO

Abstract Extracorporeal Cardiopulmonary Resuscitation (ECPR) has potential benefits compared to conventional Cardiopulmonary Resuscitation (CCPR) in children. Although no randomised trials for paediatric ECPR have been conducted, there is extensive literature..

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Association between improved compliance with enhanced recovery after cardiac surgery guidelines and postoperative outcomes: A retrospective study

Abstract Objective Enhanced recovery after cardiac surgery is a multidisciplinary clinical  that relies on a bundle of interventions, aiming to reduce the stress response to surgery and promote early recovery of..

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Clinical decision making for VA ECMO weaning in patients with cardiogenic shock A formative qualitative study

Abstract Weaning and liberation from VA ECMO in cardiogenic shock patients comprises a complex process requiring a continuous trade off between multiple clinical parameters. In the absence of dedicated international..

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Rehabilitation for adult patients undergoing extracorporeal membrane oxygenation

Abstract Background and purpose Current information on the latest rehabilitative practices is limited, with previous reviews only covering data up to October 2021, and some considering only patients on awake..

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Effect of Retrograde Autologous Priming on Coagulation Assessed by Rotation Thromboelastometry in Patients Undergoing Valvular Cardiac Surgery

Abstract Objectives To investigate the effect of retrograde autologous priming (RAP) on coagulation function using rotation thromboelastometry (ROTEM) in patients undergoing valvular cardiac surgery. Design A prospective, randomized, patient- and outcome assessor-blinded study...

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Perioperative Apixaban: Bleeding, Clotting, or Both?

Abstract Anticoagulation for Subclinical Atrial Fibrillation Recently, the ARTESIA study addressed this question in a randomized trial of 4,012 patients with subclinical atrial fibrillation identified by an implanted device, and..

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The role of inflammation and antithrombin supplementation on thromboelastographic parameters during veno-venous ECMO for respiratory failure

Abstract Introduction Extracorporeal membrane oxygenation (ECMO) may act as a driver or propagator of systemic inflammation. In turn, cytokine release can modify thromboelastographic (TEG) tests which are commonly used for..

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Extracorporeal membrane oxygenation from last resort to indispensable tool in the treatment of respiratory and/or circulatory failure

Abstract Extracorporeal membrane oxygenation (ECMO) continues to be an indispenable tool in critical care settings, in particular in patients with severe respiratory and/or cardiac failure. The COVID-19 pandemic highlighted the..

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Introduction smartcanula

Why choose smartcanula? The venous smartcanula is a disposable, wall-less canula, for less invasive canulation in conjunction with extracorporeal circulation. The smartcanula principle: “collapsed canula insertion and expansion in situ”...

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Physiology of Extracorporeal Gas Exchange

Abstract Circulating venous blood outside the body, through an artificial lung (membrane oxygenator), andreturning oxygenated blood to the patient is extracorporeal gas exchange. Oxygen and carbondioxide exchange in a membrane..

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Does Size Matter? The Effect of Size of Distal Perfusion Catheter on Acute Limb Ischemia: A Meta-Analysis

Abstract Prevention of limb ischemia in patients with venoarterial extracorporeal membrane oxygenation (VA-ECMO) is primarily achieved through the use of distal perfusion catheters (DPC). Our objective was to assess the..

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A novel versatile concept of cardioplegia delivery in cardiac surgery: The ReverseTWO cardioplegia circuit system

Abstract Nowadays, the necessity of having a cardioplegia circuit capable of being adapted in order to administer different types of cardioplegia is strategically fundamental, both for the perfusionist and for..

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How to manage differential hypoxemia during veno-arterial extracorporeal membrane oxygenation

Abstract Over the past decade, veno-arterial extracorporeal membrane oxygenation (VA-ECMO) has expanded rapidly as a salvage strategy to provide temporary circulatory and respiratory support allowing cardiac function recovery or bridging..

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A Pilot Study of Renin-Guided Angiotensin-II Infusion to Reduce Kidney Stress After Cardiac Surgery

Abstract BACKGROUND:  Vasoplegia is common after cardiac surgery, is associated with hyperreninemia, and can lead to acute kidney stress. We aimed to conduct a pilot study to test the hypothesis..

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The impact of small movements with dual lumen cannulae during venovenous extracorporeal membrane oxygenation: A computational fluid dynamics analysis

Abstract Background and objectives Venovenous Extracorporeal Membrane Oxygenation (VV ECMO) provides respiratory support to patients with severe lung disease failing conventional medical therapy. An essential component of the ECMO circuit..

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Epidemiology of anticoagulation for children supported by extracorporeal membrane oxygenation in the United States: A Pediatric Hospital Information System database…

Abstract Introduction Due to the risk of thrombosis, nearly all children supported by extracorporeal membrane oxygenation (ECMO) receive systemic anticoagulation. While heparin has traditionally been used, there are reports of..

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Conferences/Events 2024

You can meet us and learn more about SmartCanula at these events. We are waiting for you!   SECCE (National Cardiac Surgery Congress) – 2024, June 5-7 – Madrid, Spain..

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Mechanical ventilation during extracorporeal membrane oxygenation support – New trends and continuing challenges

Abstract Background The impact of mechanical ventilation on the survival of patients supported with veno-venous extracorporeal membrane oxygenation (V-V ECMO) due to severe acute respiratory distress syndrome (ARDS) remains still..

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ECMO Alone Versus ECPELLA in Patients Affected by Cardiogenic Shock: The Multicenter EVACS Study

Abstract The objective was to investigate the outcomes of concomitant venoarterial extracorporeal membrane oxygenation (ECMO) and left ventricular unloading with Impella (ECPELLA) compared with ECMO alone to treat patients affected..

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Prone positioning during extracorporeal membrane oxygenation for severe acute respiratory distress syndrome.

PRO Building solid evidence in intensive care medicine is challenging, mostly due to patient heterogeneity and concomitant treatment interactions. In the context of acute respiratory distress syndrome (ARDS), only two..

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The intricate physiology of veno-venous extracorporeal membrane oxygenation: an overview for clinicians

Abstract During veno-venous extracorporeal membrane oxygenation (V-V ECMO), blood is drained from the central venous circulation to be oxygenated and decarbonated by an artificial lung. It is then reinfused into..

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Brochure smartcanula

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The physiology of venoarterial extracorporeal membrane oxygenation - A comprehensive clinical perspective

Abstract Venoarterial extracorporeal membrane oxygenation (VA ECMO) has become a standard of care for severe cardiogenic shock, refractory cardiac arrest and related impending multiorgan failure. The widespread clinical use of..

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Left ventricular unloading in patients supported with veno-arterial extra corporeal membrane oxygenation; an international EuroELSO survey

Abstract Introduction Veno-arterial extracorporeal membrane oxygenation (V-A ECMO) improves end-organ perfusion in cardiogenic shock but may increase afterload, which can limit cardiac recovery. Left ventricular (LV) unloading strategies may aid..

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