Monthly Archives: diciembre 2024

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2024 EACTS Guidelines on perioperative medication in adult cardiac surgery

Abstract Adult cardiac surgery is an essential therapeutic approach to reduce short- and long-term mortality and morbidity in patients with acute or chronic cardiac diseases. The outcomes after cardiac surgery..

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Cardiac Contributions to Brain Health: A Scientific Statement From the American Heart Association

Abstract The burden of neurologic diseases, including stroke and dementia, is expected to grow substantially in the coming decades. Thus, achieving optimal brain health has been identified as a public..

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Impact of Skin Pigmentation on Pulse Oximetry Blood Oxygenation and Wearable Pulse Rate Accuracy: Systematic Review and Meta-Analysis

Abstract Background: Photoplethysmography (PPG) is a technology routinely used in clinical practice to assess blood oxygenation (SpO2) and pulse rate (PR). Skin pigmentation may influence accuracy, leading to health outcomes..

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International Clinical Practice Guideline Recommendations for Acute Pulmonary Embolism: Harmony, Dissonance, and Silence

Abstract Despite abundant clinical innovation and burgeoning scientific investigation, pulmonary embolism (PE) has continued to pose a diagnostic and management challenge worldwide. Aging populations, patients living with a mounting number..

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Randomized Clinical Trials on Venoarterial Extracorporeal Membrane Oxygenation in Cardiogenic Shock: Why Are They All Negative?

Abstract Cardiogenic shock (CS) is one of the most challenging areas in cardiology, where hard evidence is often limited. Several factors contribute to this scarcity. Patients with CS are typically..

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A Randomized Controlled Trial Comparing Effectiveness of Different Fibrinogen Preparations in Restoring Clot Firmness

Abstract BACKGROUND:  Different preparations of fibrinogen concentrate are currently available. Two in vitro studies demonstrated the superiority of FibCLOT (LFB) in increasing clot firmness with respect to RiaSTAP (CSL Behring)...

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Ventilation and Oxygenation During and After Adult Cardiopulmonary Resuscitation: Changing Paradigms

Abstract Cardiac arrest (CA) remains a major cause of death despite advancements in cardiopulmonary resuscitation (CPR), post-resuscitation care, and international efforts to develop evidence-based guidelines. Effectively managing ventilation and oxygenation..

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Acute brain injury risk prediction models in venoarterial extracorporeal membrane oxygenation patients with tree-based machine learning: An Extracorporeal Life Support…

Abstract Objective We aimed to determine if machine learning can predict acute brain injury and to identify modifiable risk factors for acute brain injury in patients receiving venoarterial extracorporeal membrane..

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Changing the conversation: impact of guidelines designed to optimize interprofessional facilitation of simulation-based team training

Abstract Background Interprofessional simulation-based team training (ISBTT) is commonly used to optimize interprofessional teamwork in healthcare. The literature documents the benefits of ISBTT, yet effective interprofessional collaboration continues to be..

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Accidental Lumbar Vein Cannulation During Emergent Veno-Venous Extracorporeal Membrane Oxygenation Initiation: Case Report

Abstract A 31-year-old woman at 41 weeks gestation presented after a home-delivery attempt, resulting in an intrauterine fetal demise. A cesarean section revealed purulent amniotic fluid. The patient had a..

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Efficacy of a Single Day Extracorporeal Membrane Oxygenation Training Course for Critical Care Air Transport Team Eligible Personnel

Abstract Background Extracorporeal membrane oxygenation (ECMO) is an advanced medical technology that is used to treat respiratory and heart failure. The U.S. military has used ECMO in the care of..

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Priorities for Clinical Research in Pediatric Extracorporeal Membrane Oxygenation Anticoagulation From the Pediatric Extracorporeal Membrane Oxygenation Anticoagulation CollaborativE Consensus Conference

Abstract OBJECTIVES:  To identify and prioritize research questions for anticoagulation and hemostasis management of neonates and children supported with extracorporeal membrane oxygenation (ECMO) from the Pediatric ECMO Anticoagulation CollaborativE (PEACE)..

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Anticoagulant Medications: The Pediatric Extracorporeal Membrane Oxygenation Anticoagulation CollaborativE Consensus Conference

Abstract OBJECTIVES:  To derive systematic-review informed, modified Delphi consensus regarding the medications used for anticoagulation for pediatric extracorporeal membrane oxygenation (ECMO) for the Pediatric ECMO Anticoagulation CollaborativE (PEACE). DATA SOURCES: ..

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Spinal Cord Infarction During Extracorporeal Membrane Oxygenation:A Case Series and Review of the Literature

Abstract Background:  Little is known about extracorporeal membrane oxygenation (ECMO)-related spinal cord infarction (SCI), and reports regarding this rare and catastrophic complication are rare. Here, we report two cases of..

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Assessing Venous Thrombotic Risks in Extracorporeal Membrane Oxygenation-Supported Patients: A Systematic Review and Meta-Analysis

Abstract This study investigates the prevalence and risk factors associated with venous thrombotic events in patients receiving (ECMO) support. Systematic review and meta-analysis of case-control and cohort studies. PubMed, Cochrane..

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Low Versus Standard Intensity Heparin Protocols in Adults Maintained on Extracorporeal Membrane Oxygenation: A Retrospective Cohort Study

Abstract Background:  Patients maintained on extracorporeal membrane oxygenation (ECMO) often require systemic anticoagulation to prevent circuit clotting and systemic thromboembolic complications. The optimal intensity of anticoagulation to balance the risk..

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Novel Flowable Hemostatic Agent ActiClot: Efficacy and Safety Assessment in Rat and Porcine Models

Abstract Background/Objectives: This study evaluated the hemostatic performance and safety of ActiClot (ATC), a new flowable hemostatic agent, through in vivo tests.  Methods: ATC was compared with the commercially available..

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The Ventilatory Ratio as a Predictor of Successful Weaning from a Veno-Venous Extracorporeal Membrane Oxygenator

Abstract Background:  Veno-venous extracorporeal membrane oxygenation (VV-ECMO) is a critical intervention for patients with severe lung failure, especially acute respiratory distress syndrome (ARDS). The weaning process from ECMO relies largely..

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Safety and feasibility of conversion from venoarterial to venovenous extracorporeal membrane oxygenation in pediatric patients: A case series

Abstract Introduction In children requiring venoarterial (VA) extracorporeal membrane oxygenation (ECMO) for long durations, conversion to venovenous (VV) support may be advantageous. The purpose of this study was to evaluate..

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Cardiogenic shock

Abstract Summary Cardiogenic shock is a complex syndrome defined by systemic hypoperfusion and inadequate cardiac output arising from a wide array of underlying causes. Although the understanding of cardiogenic shock..

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Post-Cardiac Arrest Care in Extracorporeal Cardiopulmonary Resuscitation

Abstract OBJECTIVES: Extracorporeal cardiopulmonary resuscitation (ECPR) serves as a lifesaving intervention for patients experiencing refractory cardiac arrest. With its expanding usage, there’s a burgeoning focus on improving patient outcomes through..

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“Awake” Cannulation of Patients for Venovenous Extracorporeal Membrane Oxygen: An Analysis of the Extracorporeal Life Support Organization Registry

Abstract IMPORTANCE:  “Awake” cannulation for venovenous extracorporeal membrane oxygenation (ECMO), where patients remain spontaneously breathing without invasive mechanical ventilation during the cannulation procedure, may reduce lung injury from positive pressure..

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Cardiac Function Decline After General Anesthesia and Cardiac Catheterization in Pediatric Cardiac Transplant Recipients

Abstract Background Pediatric cardiac transplant recipients undergo elective cardiac catheterization and endomyocardial biopsy (CC/EMB) for graft dysfunction surveillance often facilitated by general anesthesia (GA). GA and positive pressure ventilation (PPV)..

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Heparin treatment is associated with a delayed diagnosis of Alzheimer’s dementia in electronic health records from two large United States…

Abstract Recent studies suggest that heparan sulfate proteoglycans (HSPG) contribute to the predisposition to, protection from, and potential treatment and prevention of Alzheimer’s disease (AD). Here, we used electronic health..

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CIRBP Aggravation of Cardiac Fibrosis after Myocardial Infarction during ECMO Assistance

Abstract Background: Cold-induced RNA binding protein (CIRBP) is widely involved in critical physiological processes of myocardial fibrosis (MF), a crucial mechanism of cardiac insufficiency in myocardial infarction (MI). However, whether CIRBP..

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Systemic Inflammatory Responses in ECMO-Treated Patients: A Systematic Reviews and Meta-Analysis

Abstract Background: Extracorporeal membrane oxygenation (ECMO) is associated with significant inflammatory reactions that can impact patient outcomes. This meta-analysis aimed to evaluate the impact of ECMO on the functional ability of..

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Exploring Intraoperative Cognitive Biases in Cardiac Surgery Teams

Abstract This study focuses on understanding the influence of cognitive biases in the intra-operative decision-making process within cardiac surgery teams, recognizing the complexity and high-stakes nature of such environments. We..

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Association Between Individualized Versus Conventional Blood Glucose Thresholds and Acute Kidney Injury After Cardiac Surgery: A Retrospective Observational Study

Abstract Objectives This study was designed to compare individualized and conventional hyperglycemic thresholds for the risk of  (AKI) after cardiac surgery. Design This was an observational study. Setting The study took..

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Hemodynamic Effect of Hydroxocobalamin During Extracorporeal Membrane Oxygenation

Abstract Background: Hydroxocobalamin increases systemic blood pressure through nitric oxide pathway suppression. However, its effects on hypotension during extracorporeal membrane oxygenation (ECMO) are unknown. The objective of this study was to..

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Impact of Blood Sampling Methods on Blood Loss and Transfusion After Pediatric Cardiac Surgery: An Observational Study

Abstract Objectives The aims of this study were to assess the impact of the closed-loop sampling method on  and the need for  in pediatric patients following cardiac surgery. Design Retrospective observational study...

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