Yearly Archives: 2022

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The emerging concept of fluid tolerance: A position paper

Abstract Fluid resuscitation is a core component of emergency and critical care medicine. While the focus of clinicians has largely been on detecting patients who would respond to fluid therapy, relatively..

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Histidine–tryptophan–ketoglutarate solution versus multidose cardioplegia for myocardial protection in cardiac surgeries: a systematic review and meta-analysis

Abstract Background Surgical procedures in the heart requires protection of the heart from ischemia–reperfusion injury. Cardioplegia is the primary myocardial protective method in use. Histidine–tryptophan–ketoglutarate (HTK) solution is an intracellular..

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Simultaneous electrical online estimation of changes in blood hematocrit and temperature in cardiopulmonary bypass

Abstract Two equations have been developed from multi-frequency measurements of blood impedance Zb for a simultaneous electrical online estimation of changes in blood hematocrit ΔH [%] and temperatures ΔT [K] in cardiopulmonary bypass (CPB). Zb of fixed blood..

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Pharmacokinetics of Cefazolin in Patients With Obesity Undergoing Surgery Requiring Cardiopulmonary Bypass

Abstract Objective The authors’ objective was to determine the adequacy of an institutional standard dosing practice for infection prophylaxis in open cardiac surgery in patients heavier than 120 kg undergoing..

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Bacterial endocarditis of mitral valve

Patient with renal transplantation and bacterial endocarditis of mitral valve undergone MVR with two stage cannulation valve débridement and annulus reconstruction with good post op course.  Dr.Sam Zeraatian Nejad Davani,..

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Pulmonary valve replacement with previous trans annular patch

Pulmonary valve replacement in patient with previous trans annular patch and severe Pulmonary insufficiency.  Dr.Sam Zeraatian Nejad Davani, CEO of rockingham medical research ADKWA center as well as Head of..

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Minimized Extracorporeal Circulation Is Associated with Reduced Plasma Levels of Free-Circulating Mitochondrial DNA Compared to Conventional Cardiopulmonary Bypass: A Secondary…

Abstract The use of minimized extracorporeal circulation (MiECC) during cardiac surgery is associated with a reduced inflammatory reaction compared to conventional cardiopulmonary bypass (cCPB). Since it is unknown if MiECC..

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Understanding base excess (BE): merits and pitfalls

Abstract Base excess (BE) was introduced by Siggaard-Andersen in 1960 as an answer to the forty-year-long quest for a reliable, stand-alone marker of metabolic acidosis/alkalosis, independent from co-existing respiratory derangements,..

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Role of Hypothermia in Adult Cardiac Surgery Patients: A Systematic Review and Meta-analysis

Abstract Objective To review studies that assessed systemic hypothermia as an organ protection strategy in adults undergoing cardiac surgery with cardiopulmonary bypass. Design A systematic review and meta-analysis. Setting and..

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On-Hours Compared to Off-Hours Pediatric Extracorporeal Life Support Initiation in the United States Between 2009 and 2018—An Analysis of the…

Abstract OBJECTIVES:  We aimed to investigate whether there are differences in outcome for pediatric patients when extracorporeal life support (ECLS) is initiated on-hours compared with off-hours. DESIGN:  Retrospective cohort study...

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Safe sedation management using volatile anesthetics during cardiopulmonary bypass

Abstract Several pieces of evidence suggest that volatile anesthetics (VAs), which were originally used as sedatives, have myocardial protective effects against cardiac ischemia–reperfusion injury. In Europe and the United States,..

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Ex Vivo Lung Perfusion: A Review of Current and Future Application in Lung Transplantation

Abstract The number of waitlisted lung transplant candidates exceeds the availability of donor organs. Barriers to utilization of donor lungs include suboptimal lung allograft function, long ischemic times due to..

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Preoperative Iron Supplementation in Pediatric Cardiac Surgical Patients: A Preliminary Single-Center Experience

Abstract Objective To assess preoperative hemoglobin and perioperative red blood cell transfusion in children undergoing cardiac surgery after the implementation of a preoperative patient blood management (PBM) clinic with oral..

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Injection of Recombinant Tissue Plasminogen Activator into Extracorporeal Membrane Oxygenators Postpones Oxygenator Exchange in COVID-19

Abstract Coronavirus disease 2019 (COVID-19) has drastically increased the number of patients requiring extracorporeal life support. We investigate the efficacy and safety of low-dose recombinant tissue-type plasminogen activator (rtPA) injection..

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Impact of Heparin- or Nonheparin-Coated Circuits on Platelet Function in Pediatric Cardiac Surgery

Abstract Background: Extracorporeal circuit coating has been shown to improve coagulation derangements during pediatric cardiopulmonary bypass (CPB). This study compared platelet function and hemostasis activation in pediatric cardiac surgery conducted with..

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Persistent cardiac injury – An important component of long COVID-19 syndrome

Abstract As the COVID-19 pandemic goes on, we continue to identify the long-term complications or symptoms among patients who recovered from this infection, be it mild or severe.    These..

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Efficacy, Safety, and Strategies for Recombinant-Activated Factor VII in Cardiac Surgical Bleeding: A Narrative Review

Abstract As perioperative bleeding continues to be a major source of morbidity and mortality in cardiac surgery, the search continues for an ideal  for use in this patient population. Transfusion of..

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Extracorporeal interval support for organ retrieval delivery regional experience with sharing equipe, equipment & expertise to increase conventionally defined as…

Abstract Donation after circulatory death (DCD) programs are expanding in Europe, in the attempt to expand donors pool. Even in controlled DCD donors, however, a protracted warm ischemia time occurring..

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Early Blood Pressure Variables Associated With Improved Outcomes in VA-ECLS: The ELSO Registry Analysis

Abstract Background As utilization of veno-arterial  (VA-ECLS) in treatment of  (CS) continues to expand, clinical variables that guide clinicians in early recognition of myocardial recovery and therefore, improved survival, after VA-ECLS are..

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Patient blood management in critically ill children undergoing cardiac surgery: A cohort study

Abstract Objective The objective of this study was to audit current patient blood management practice in children throughout cardiac surgery and paediatric intensive care unit (PICU) admission. Design This was..

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Disseminated intravascular coagulation: epidemiology, biomarkers, and management

Abstract Disseminated intravascular coagulation (DIC) is a systemic activation of the coagulation system, which results in microvascular thrombosis and, simultaneously, potentially life-threatening haemorrhage attributed to consumption of platelets and coagulation..

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Echocardiography in Anderson-Fabry Disease

Abstract Echocardiography is the most common diagnostic tool to screen for Fabry cardiomyopathy as it is fast, non-invasive, low-cost, widely available, easily applicable and reproducible. Echocardiography is the first-line investigation,..

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Temporary Left Ventricular Support Device as a Bridge to Heart-Liver or Heart-Kidney Transplant: Pushing the Boundaries of Temporary Support

Abstract In patients with severe cardiogenic shock, temporary mechanical circulatory support has become a viable strategy to bridge patients to heart transplantation. However, end-stage heart failure is often associated with progressive organ..

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New trend: Surgical correction of Ebstein's anomaly using modified cone repair and a combination of different techniques

Abstract Background Ebstein's anomaly,a rare cardiac disease that accounts for <1% of all congenital heart diseases, is a right ventricular myopathy with varying degrees of delamination in the endocardium under..

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Severe mitral stenosis and tricuspid regurgitation

Patient with severe MS and TR undergone single incision MV replacement and TV repair with modified repair technique bilateral tricuspid valve weaned from CPB uneventfully.  Dr.Sam Zeraatian Nejad Davani, CEO..

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Ascending aorta and arch dissection

Patient with ascending aorta and arch dissection undergone direct arch cannulation and total circulation arrest with valve preservation ascending aorta replacement and innominate artery reimplantation. [playlist ids="29322"]   Dr.Sam Zeraatian..

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Veno Venöz Ekstrakorporeal Membran Oksijenasyonu (VV ECMO) ile Desteklenen Yetişkin Hastaların Yönetimi.

Veno Venöz Ekstrakorporeal Membran Oksijenasyonu (VV ECMO) ile Desteklenen Yetişkin Hastaların Yönetimi. Düzenleyen : Perfüzyonist Sedat Gündöner GİRİŞ Bu kılavuzda VV ECMO ile desteklenen yetişkin hastalar klinik yönetimi için öneriler..

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Use of Cytosorb in persistent hyperinflammation associated with lung infiltrates and pleural effusion

This case reports on a 63-year-old male, who was admitted to the hospital with a 2-month history of exertional shortness of breath, a periodic cough with purulent sputum and right..

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Redo mitral valve operation

Redo mitral valve operation with previous ascending aorta replacement.  Dr.Sam Zeraatian Nejad Davani, CEO of rockingham medical research ADKWA center as well as Head of IUMS transplant and cardiovascular surgery..

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