Perfusfind S.L.
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Unveiling the hidden risk: a case of severe jaundice triggered by intra-aortic balloon pump after cardiac surgery

Abstract Background The Intra-Aortic Balloon Pump (IABP) is a widely utilized technique to provide circulatory support for critically ill patients with cardiac dysfunction. While IABP therapy offers clinical benefits, the..

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Litigation associated with the use of extracorporeal membrane oxygenation

Abstract Introduction Extracorporeal membrane oxygenation (ECMO) is a high-risk treatment but the legal risk surrounding its use is unknown. Methods Retrospective review of the Westlaw legal database was used to..

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Does Levosimendan hasten veno-arterial ECMO weaning? A propensity score matching analysis

Abstract Background Preliminary evidence from small, single-center studies suggests levosimendan may improve the likelihood of successful venoarterial extracorporeal membrane oxygenation (VA-ECMO) weaning in patients with cardiogenic shock. However, the literature..

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The Readability of Extracorporeal Membrane Oxygenation Patient Education Materials

Abstract The National Institute of Health (NIH) recommends that healthcare education material be written at a 6th–7th grade reading level. There are yet to be studies that investigate the readability..

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The Power of Education to Reduce the Carbon Footprint of Volatile Anesthetics in Clinical Practice

Abstract BACKGROUND:  Due to their chemical nature as fluorinated hydrocarbon compounds, volatile anesthetics are highly potent greenhouse gases, with desflurane having by far the largest CO2-equivalent (CO2e) footprint. In everyday..

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Fibrinogen levels and bleeding risk in adult extracorporeal cardiopulmonary resuscitation: multicenter observational study subanalysis

Abstract Introduction Venoarterial extracorporeal membrane oxygenation (VA-ECMO) is an essential life-support system in critical care specifically engineered to assist cardiac and respiratory function by externally maintaining blood perfusion and oxygenation..

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Brief hypothermic oxygenated perfusion provides cardioprotection in a pig model of donation after circulatory death

Abstract OBJECTIVES Donation after circulatory death provides excellent patient outcomes in heart transplantation; however, warm ischaemic graft damage remains a concern. We have reported that a brief period of hypothermic..

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Direct perfusion for mesenteric ischaemia in acute type A aortic dissection: a glimpse into the mist of uncertainties

Abstract Management of mesenteric malperfusion or ischaemia in patients with acute type A aortic dissection (ATAAD) has been controversial and it remains unclear as to the best strategy for mesenteric..

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A Retrospective Analysis of the Effects of Concomitant Use of Intra-Aortic Balloon Pump (IABP) and Veno-Arterial Extracorporeal Membrane Oxygenation (va-ECMO)…

Abstract Background/Objectives: Brain ischemia is a frequent complication in patients undergoing veno-arterial extracorporeal membrane oxygenation (va-ECMO) therapy due to hypoperfusion, low oxygenation, and thromboembolism. While concomitant intra-aortic balloon pump (IABP) therapy..

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Exploring the experiences of cardiovascular perfusionists during philanthropic cardiac surgery in low-income countries

Abstract Background: Medical mission trips address the global burden of cardiac disease, particularly in Sub-Saharan Africa, where limited access to cardiac surgery exacerbates challenges faced by affected individuals. However, a..

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Retained blood syndrome after cardiac surgery

Abstract OBJECTIVES Retained blood syndrome (RBS) is defined as the postoperative retention of blood within the thoracic cavity. In addition to the mechanical impacts on cardiac and pulmonary function, RBS..

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Conventional Cardiopulmonary Resuscitation Versus Extracorporeal Membrane Oxygenation-Assisted CPR in Children: A Retrospective Analysis of Outcomes and Factors Associated with Conversion…

Abstract Background/Objectives: Conventional cardiopulmonary resuscitation (CCPR) has been the foundational resuscitation approach for decades. Where CCPR is unsuccessful, extracorporeal membrane oxygenation-assisted CPR (ECPR) may improve outcomes. Predicting failure of CCPR..

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Access to hospitals with extracorporeal membrane oxygenation capabilities as a potential of driver of disparities

Abstract Extracorporeal membrane oxygenation (ECMO) is a rapidly growing resource for the most critically ill patients with respiratory and/or circulatory failure. [1,2] ECMO is one of the most resource intensive..

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Flow Mode-Dependent Regulation of von Willebrand Factor Degradation in Mechanical Circulatory Support

Abstract Background Among patients reliant on continuous-flow (CF) mechanical circulatory support devices, bleeding is primarily caused by an acquired von Willebrand factor (vWF) deficiency, precipitated by the high shear stress..

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Is altitude friend or foe in unrepaired congenital heart disease? A case report

Abstract Background Some unrestrictive congenital shunts put patients at high risk for developing irreversible pulmonary vascular disease if not closed in the first year of life. Living at high altitude..

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Impaired cerebral autoregulation in children

Abstract Managing acute brain injury involves protecting the brain from secondary injury by addressing the mismatch between metabolic demand and cerebral perfusion. Observational studies have associated impaired cerebral autoregulation, a..

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Increased VA-ECMO Pump Speed Reduces Left Atrial Pressure: Insights from a Novel Biventricular Heart Model

Abstract Background and aims:  The effect of veno-arterial extracorporeal membrane oxygenation (VA-ECMO) on left atrial pressure (LAP) in the presence of interventricular interaction and the Frank–Starling mechanism is unknown. We..

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Effect of Respiratory Support Type and Total Duration on Weaning From Venovenous Extracorporeal Membrane Oxygenation in COVID-19 Patients

Abstract Background: We evaluated the impact of noninvasive respiratory support (NRS) and invasive mechanical ventilation duration before venovenous extracorporeal membrane oxygenation (VV-ECMO) on weaning from venovenous ECMO and survival.   Methods: In..

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Minimal invasive extracorporeal circulation versus conventional cardiopulmonary bypass in cardiac surgery: a contemporary systematic review and meta-analysis

Abstract OBJECTIVES The question whether minimally invasive extracorporeal circulation (MiECC) represents the optimal perfusion strategy in cardiac surgery remains unanswered. We sought to systematically review the entire literature and thoroughly..

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Vascular Closure Device vs Open Decannulation for Femoral Venoarterial Extracorporeal Membrane Oxygenation

Abstract Background Traditional decannulation of femoral venoarterial (VA) extracorporeal membrane oxygenation (ECMO) involves femoral cutdown. Percutaneous methods have been developed, but data supporting their use are limited. This study sought..

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Venoarterial Extracorporeal Membrane Oxygenation Therapy in Patients with Sickle Cell Disease: Case Series and Review for Intensive Care Physicians

Abstract Sickle cell disease (SCD) is associated with substantial morbidity and early mortality in afflicted adults. Cardiopulmonary complications that occur at increased frequency in SCD such as pulmonary embolism, pulmonary..

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Characteristics and risk factors of delirium in patients on veno-arterial extracorporeal membrane oxygenation

Abstract Purpose Sparse data exist on delirium in VA-ECMO. We aim to describe the characteristics, risk factors, and outcomes of delirium in VA-ECMO. Methods We retrospectively reviewed adults’s electronic medical..

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Redefining ECMO cannulation: A case for TEE-guided VP ECMO and flotation catheter

Abstract Venopulmonary ECMO (VP ECMO) is an advanced support strategy for patients with severe respiratory failure and right ventricular (RV) dysfunction, providing pulmonary protection by oxygenating blood and unloading the..

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Effect of cardiopulmonary bypass on late-onset hyperlactatemia after pediatric cardiac surgery

Abstract Background: This study aimed to investigate the effect of operative and postoperative parameters on late-onset hyperlactatemia (LOHL) after cardiac surgery in the pediatric patient population.Methods: One hundred fifty-nine ventricular septal defect..

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Trauma-related psychopathologies after extracorporeal membrane oxygenation support: A systematic review and meta-analysis

Abstract Extracorporeal Membrane Oxygenation (ECMO) use is associated with substantial psychiatric morbidity in patients and their families. This systematic review and meta-analysis quantifies the prevalence of post-traumatic stress disorder (PTSD),..

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Performance Comparison of Centered and Tilted Blunt and Lighthouse Tip Cannulae for Drainage in Extracorporeal Life Support

Abstract Introduction Extracorporeal membrane oxygenation is a lifesaving treatment for patients with refractory acute respiratory, circulatory, or combined cardiopulmonary failure. The patient is cannulated with one or two cannulae for..

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Prolonged Use of Extracorporeal Membrane Oxygenators for COVID-19–Associated Acute Respiratory Distress Syndrome: A Retrospective Analysis

Abstract Whether an anticoagulation strategy combining bivalirudin and aspirin during extracorporeal membrane oxygenation (ECMO) would prolong oxygenator use is unknown. No clear data exist on oxygenator life span during prolonged..

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Early Intra-Aortic Balloon Support for Heart Failure-Related Cardiogenic Shock: A Randomized Clinical Trial

Abstract Background The impact of intra-aortic balloon pump (IABP) on survival and successful bridging to heart replacement therapies (HRT) in patients with heart failure–cardiogenic shock (HF-CS) remains unclear. Objectives The..

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Cerebral Inflammation in an Animal Ischemia–Reperfusion Model Comparing Histidine-Tryptophan-α-Ketoglutarate and Del Nido Cardioplegia

Abstract Brain injury and cerebral inflammation are frequent complications following cardiopulmonary bypass (CPB) resulting in neurocognitive dysfunction, encephalopathy, or stroke. We compared cerebral inflammation induced by del Nido and histidine-tryptophan-α-ketoglutarate..

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Branch-first technique with continuous perfusion in aortic arch repair—our initial experience

Abstract The branch-first technique (BFT) for aortic arch replacement eliminates deep hypothermia and global circulatory arrest, reducing cardiopulmonary bypass and ischemic times. We present our initial experience with BFT in..

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