Perfusfind S.L.
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CytoSorb in the management of severe septic shock after coronary artery bypass graft surgery

This case reports on a 58-year-old male was hospitalized with a 2-day history of chest pain and dyspnea on exertion (New York Heart Association Class III).   [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2021/02/CytoSorb-in-the-management-of-severe-septic-shock-after-coronary-artery-bypass-graft-surgery_compressed.pdf" title="CytoSorb..

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Cytosorb for Management of Acute Kidney Injury due to Rhabdomyolysis in a Child

This case reports on a 6-year-old, previously healthy girl who presented to the hospital with a febrile illness and profound pain in her lower extremities.   [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2021/02/Cytosorb-for-Management-of-Acute-Kidney-Injury-due-to-Rhabdomyolysis-in-a-Child_compressed.pdf" title="Cytosorb for..

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Terapia CytoSorb: Manejo de la tormenta de citokinas en pacientes con COVID-19

Actualmente se dispone de opciones de tratamiento limitadas para pacientes graves de COVID-19 en UCI, pudiendo alcanzar tasas de mortalidad de hasta el 50 %.   [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2021/02/cytosorb-covid19_compressed.pdf" title="cytosorb covid19_compressed"]  

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CytoSorb complementa la terapia ECMO

El tratamiento con CytoSorb se aplicó de forma prospectiva y se analizó de forma retrospectiva en el grupo de control, en los pacientes con sepsis de orígen pulmonar y SDRA..

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Neonatal and Pediatric General and Cardiac Anaesthesia and ICU: what’s new in 2017/2018 ? -Bari Pediatric Hospital Experience-Italy

Abstract This review wants to give an overview to most of the controversial fields in the clinical therapeutic assistance in neonatal and pediatric general and cardiothoracic surgery in anaesthesia and..

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In vitro assays and clinical trials in red blood cell aging: Lost in translation

Abstract The age of  (EC) in  and the  when transfusing long-term-stored EC are highly controversial issues. Whereas the definition of a short-term-stored EC or a long-term-stored EC is unclear in clinical trials, data..

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Identification of Plasma Metabolites Prognostic of Acute Kidney Injury after Cardiac Surgery with Cardiopulmonary Bypass

Abstract Acute kidney injury (AKI) is a frequent complication after cardiopulmonary bypass, but early detection of postoperative AKI remains challenging. Protein biomarkers predict AKI excellently in homogeneous cohorts but are..

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Assessment of Cerebral Autoregulation Patterns with Near-infrared Spectroscopy during Pharmacological-induced Pressure Changes

Abstract Background: Previous work has demonstrated paradoxical increases in cerebral oxygen saturation (ScO2) as blood pressure decreases and paradoxical decreases in ScO2 as blood pressure increases. It has been suggested that..

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Feasibility of smaller arterial cannulas in venoarterial extracorporeal membrane oxygenation

Abstract To facilitate venoarterial extracorporeal membrane oxygenation (ECMO) insertion for cardiogenic shock, we recently adopted a strategy of using a 15F arterial cannula in all patients, rather than 1 designed..

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Extracorporeal Life Support

Abstract This is a review of the University of Michigan experience with extracorporeal life support (ECLS) also known as extracorporeal membrane oxygenation (ECMO). Two thousand patients were managed with ECMO..

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Visceral organ protection in aortic arch surgery: safety of moderate hypothermia

Abstract OBJECTIVES Although antegrade selective cerebral perfusion (ASCP) provides good brain protection during aortic arch surgery, the issue of distal organ protection during circulatory arrest remains to be clarified. The..

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Platelet factor 4/heparin-particle gel immunoassay (PaGIA) is a weak method for heparin-induced thrombocytopenia (HIT) evaluation of post cardio-pulmonary bypass surgery…

Abstract Diagnosis of heparin induced thrombocytopenia (HIT) is not always easy, especially when a confirmatory functional test is not available. In most cases the diagnosis relies on the combination of..

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The Efficacy, Safety and Cost-Effectiveness of Intra-Operative Cell Salvage in High-Bleeding-Risk Cardiac Surgery with Cardiopulmonary Bypass: A Prospective Randomized and…

Abstract Objective: Intra-operative cell salvage (CS) was reported to be ineffective, safe and not cost-effective in low-bleeding-risk cardiac surgery with cardiopulmonary bypass (CPB), but studies in high-bleeding-risk cardiac surgery are limited...

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Post-Operative Bleeding Risk Stratification in Cardiac Pulmonary Bypass Patients Using Artificial Neural Network

Abstract The prediction of bleeding risk in cardiopulmonary bypass (CPB) patients plays a vital role in their postoperative management. Therefore, an artificial neural network (ANN) to analyze intra-operative laboratory data..

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Ex-vivo perfusion of donor hearts for human heart transplantation (PROCEED II): a prospective, open-label, multicentre, randomised non-inferiority trial

Abstract Background The Organ Care System is the only clinical platform for ex-vivo perfusion of human donor hearts. The system preserves the donor heart in a warm beating state during..

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Ventricular assist devices: The future is now

Abstract Heart failure has become a global epidemic. For advanced heart failure, a broad assortment of device options have been introduced for both acute and prolonged intervals of  assistance. Durable implantable  (VADs)..

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Severe antiphospholipid syndrome and cardiac surgery: Perioperative management

Abstract Antiphospholipid syndrome is an antiphospholipid antibody-mediated prothrombotic state leading to arterial and venous thrombosis. This condition alters routine in-vitro coagulation tests, making results unreliable. Antiphospholipid syndrome patients requiring cardiac..

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Intra‐aortic balloon pump counterpulsation (IABP) for myocardial infarction complicated by cardiogenic shock

Abstract Background Intra‐aortic balloon pump counterpulsation (IABP) is currently the most commonly used mechanical assist device for patients with cardiogenic shock due to acute myocardial infarction. Although there has been..

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Timing and Strategy for Weaning From Venoarterial ECMO are Complex Issues

Abstract Objective Weaning from venoarterial extracorporeal membrane oxygenation (VA ECMO) usually is performed without clear guidelines; yet, patients still die after removal of extracorporeal circulation because of inadequate heart or..

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Tissue near infra red spectroscopy change is not correlated with patients' outcome in elective cardiac surgery

Abstract Background Microcirculatory disturbances following cardiac surgery with cardiopulmonary bypass (CPB) are thought to be at the origin of organ dysfunction, although few studies have correlated microvascular alterations with outcome...

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The prothrombotic paradox of severe obesity after cardiac surgery under cardiopulmonary bypass

Abstract Background Obesity is suggested to reduce postoperative bleeding in patients undergoing cardiac surgery with cardiopulmonary bypass (CPB) but perioperative hemostasis variations have not been studied. Therefore, we investigated the..

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Multidisciplinary Approach to Transvenous Lead Extraction: A Single Center’s Experience

Abstract Objective To evaluate the success and complication rates of a single center’s multidisciplinary approach to transvenous lead extraction. Setting One university hospital. Participants One hundred ninety-five patients scheduled for..

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Red Blood Cells and Mortality After Coronary Artery Bypass Graft Surgery: An Analysis of 672 Operative Deaths

Abstract Background Prior studies have implicated transfusion as a risk factor for mortality in coronary artery bypass graft surgery (CABG). To further our understanding of the true association between transfusion..

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Prolonged Outbreak of Mycobacterium chimaera Infection After Open-Chest Heart Surgery

Abstract Background. Invasive Mycobacterium chimaera infections were diagnosed in 2012 in 2 heart surgery patients on extracorporeal circulation. We launched an outbreak investigation to identify the source and extent of the potential outbreak..

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Genetic variation influences the risk of bleeding after cardiac surgery: novel associations and validation of previous findings

Abstract Background Severe post‐operative bleeding in cardiac surgery is associated with increased morbidity and mortality. We hypothesized that variation in genetic susceptibility contributes to post‐operative bleeding in addition to clinical..

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Combined Cerebral and Renal Near-Infrared Spectroscopy After Congenital Heart Surgery

Abstract The maintenance of an adequate oxygen supply to tissues after congenital heart surgery is essential for good outcomes. The objective of this study was to assess the usefulness of..

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Peripheral circulation evaluation with near-infrared spectroscopy in skeletal muscle during cardiopulmonary bypass

Abstract Background: We designed a non-invasive, observational, real-time study, using near-infrared spectroscopy (NIRS) to assess the in vivo effects of cardiopulmonary bypass (CPB) on patients’ skeletal muscle as well as..

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Protection strategies during cardiopulmonary bypass

Abstract Purpose of review  To provide an update of research findings regarding the protection strategies utilized for patients undergoing cardiopulmonary bypass (CPB), including perioperative ventilatory strategies, different anesthetic regimens, and..

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Cardiogenic Shock

Cardiogenic Shock The unresolved clinical challenge. Cardiogenic shock (CS) can present in many different stages. It ranges from those at high risk of developing shock to those critically ill with..

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Sensation Fiber-optic IAB Catheter

Smaller catheters are better for the patient, potentially reducing vascular complications. Sensation 7 Fr. is the smallest IAB catheter available today.   [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2021/02/ca_sensation_brochure_9878_rev_a_eng-en-global_compressed.pdf"]  

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