Perfusfind S.L.
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Antithrombin III is associated with acute liver failure in patients with end-stage heart failure undergoing mechanical circulatory support

Abstract Objective There are few data on the role of  in patients with end-stage heart failure supported by mechanical . The aim of our study was to investigate predictors for  in patients with..

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Thirty-Year Mortality After Coronary Artery Bypass Graft Surgery

Abstract Background Data are sparse on long-term mortality after coronary artery bypass graft (CABG) surgery. We examined short-term and long-term mortality of patients undergoing CABG surgery and a general population..

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Monitoring the quality of cardiac surgery based on three or more surgical outcomes using a new variable life-adjusted display

Abstract Quality problem or issue The traditional variable life-adjusted display (VLAD) is a graphical display of the difference between expected and actual cumulative deaths. The VLAD assumes binary outcomes: death..

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Air in intravenous lines: a need to review old opinions

Abstract At the time of writing this editorial, I have been in health care for exactly 45 years. These years have taken me through many challenging settings, including intensive cares,..

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Development and Evaluation of Heartbeat: A Machine Perfusion Heart Preservation System

Abstract Static cold storage is accompanied with a partial safe ischemic interval for donor hearts. In this current study, a machine perfusion system was built to provide a better preservation..

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Use of CytoSorb in a patient with septic shock in the context of mastitis and gangrenous cholecystitis

This report describes the case of a 63-year-old female patient, who was admitted to the Intensive Care Unit with the diagnosis of septic shock. [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2021/03/caso-semana-cyto_compressed.pdf" title="caso semana cyto_compressed"]

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Neuroprotective effect of pressure-oriented flow regulation and pH-stat management in selective antegrade brain perfusion during total aortic arch repair

Abstract OBJECTIVES The aim of this study was to assess the safety and effectiveness of our selective antegrade brain perfusion (SABP) strategy, which is characterized by moderate hypothermic and low-pressure..

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Shortening cardioplegic arrest time in patients undergoing combined coronary and valve surgery: results from a multicentre randomized controlled trial: the…

Abstract OBJECTIVES:  Combined coronary artery bypass grafting and valve surgery requires a prolonged period of cardioplegic arrest (CA) predisposing to myocardial injury and postoperative cardiac-specific complications. The aim of this..

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Clear fluids fasting for elective paediatric anaesthesia

Guidelines for the management of pre-operative paediatric clear fluid fasting historically recommend a minimum of 2 h. In particular, the published guideline from European Society of Anaesthesiology (ESA) in 2011,..

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European Society of Anaesthesiology evidence-based and consensus-based guideline on postoperative delirium

The purpose of this guideline is to present evidence-based and consensus-based recommendations for the prevention and treatment of postoperative delirium. The cornerstones of the guideline are the preoperative identification and..

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International survey on the perioperative management of pulmonary endarterectomy: the perfusion perspective

Abstract Introduction: Pulmonary endarterectomy (PEA) is the most effective treatment available for chronic thromboembolic pulmonary hypertension (CTEPH). Patient selection, surgical technique and perioperative management have improved patient outcomes, which are..

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Measurement of gaseous microemboli in the prime before the initiation of cardiopulmonary bypass

Abstract Introduction: The use of cardiopulmonary bypass is associated with a risk of neurocognitive deficit caused by gaseous microemboli. Flushing the empty bypass circuit with carbon dioxide, which is more..

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Silicon Micropore‐Based Parallel Plate Membrane Oxygenator

Abstract Extracorporeal membrane oxygenation (ECMO) is a life support system that circulates the blood through an oxygenating system to temporarily (days to months) support heart or lung function during cardiopulmonary..

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Fluid Management in Cardiac Surgery: Results of a Survey in European Cardiac Anesthesia Departments

Abstract Objective To evaluate the current practice of perioperative fluid management in cardiac surgery patients. Design Multiple choice survey with 26 questions about existing practice of perioperative fluid management in..

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Hemodilution on Cardiopulmonary Bypass: Thromboelastography Patterns and Coagulation-Related Outcomes

Abstract Objective  has been associated with both  and  in studies based on  (TEG). Severe hemodilution during  (CPB) is a risk factor for morbidity in cardiac surgery. This study investigated the effects of different degrees..

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Safety of nitric oxide added to the ECMO circuit: a pilot study in children

Abstract We describe our experience of 30 consecutive children supported with ECMO and receiving 20 ppm of nitric oxide in the oxygenator of the ECMO circuit. Administration of nitric oxide..

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Independent Predictors of the Duration and Overall Burden of Postoperative Delirium After Cardiac Surgery in Adults: An Observational Cohort Study

Abstract Objective  (POD) is a common complication after cardiac surgery and is associated with increased patient morbidity and mortality. The objective of this study was to identify risk factors for..

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Posttransfusion Increase of Hematocrit per se Does Not Improve Circulatory Oxygen Delivery due to Increased Blood Viscosity

Abstract BACKGROUND:  Blood transfusion is used to treat acute anemia with the goal of increasing blood oxygen-carrying capacity as determined by hematocrit (Hct) and oxygen delivery (DO2). However, increasing Hct..

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Remote ischaemic preconditioning reduces acute kidney injury in adult patients undergoing cardiac surgery with cardiopulmonary bypass: a meta-analysis

Abstract This article represents the first attempt to perform a pooled analysis about remote ischaemic preconditioning (RIPC) in reduction of acute kidney injury (AKI) of adult patients undergoing cardiac surgery..

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Direct oral anticoagulants and heparins: laboratory values and pitfalls in ‘bridging therapy’

Abstract OBJECTIVES:  The three direct oral anticoagulants (DOACs) dabigatran, apixaban and rivaroxaban are now widely used in clinical practice. For patients requiring perioperative interruption of DOACs, heparin bridging is still..

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Aortic root surgery with circulatory arrest: Predictors of prolonged postoperative hospital stay

Abstract Objective Little is known about the outcomes of  operations that involve inducing hypothermic circulatory arrest for relatively extensive proximal . We attempted to identify predictors of postoperative hospital length of stay..

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NGAL expression during cardiopulmonary bypass does not predict severity of postoperative acute kidney injury

Abstract Background Renal injury is a serious complication after cardiac surgery and therefore, early detection and much more prediction of postoperative kidney injury is desirable. Neutrophil gelatinase-associated lipocalin (NGAL) is..

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Myocardial energy metabolism and ultrastructure with polarizing and depolarizing cardioplegia in a porcine model.

Abstract OBJECTIVES:  This study investigated whether the novel St. Thomas’ Hospital polarizing cardioplegic solution (STH-POL) with esmolol/adenosine/magnesium offers improved myocardial protection by reducing demands for high-energy phosphates during cardiac arrest..

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External validation of predictive models for acute kidney injury following cardiac surgery

Abstract BACKGROUND  Four predictive models for acute kidney injury associated with cardiac surgery were developed by Demirjian in the United States in 2012. However, the usefulness of these models in..

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Recirculation in Extracorporeal Membrane Oxygenation: The Warning Comes From the Cannula

We are writing to point out a simple clinical sign in a pedagogic way, about recirculation in venovenous extracorporeal membrane oxygenation (ECMO). These last years, ECMO has emerged as a..

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Enhanced Hemocompatibility and In Vivo Analytical Accuracy of Intravascular Potentiometric Carbon Dioxide Sensors via Nitric Oxide Release

Abstract In this letter, the innate ability of nitric oxide (NO) to inhibit platelet activation/adhesion/thrombus formation is employed to improve the hemocompatibility and in vivo accuracy of an intravascular (IV) potentiometric PCO2 (partial pressure..

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Air embolism: diagnosis and management

Abstract Air embolism is an uncommon, but potentially life-threatening event for which prompt diagnosis and management can result in significantly improved patient outcomes. Most air emboli are iatrogenic. Arterial air..

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Do we have enough evidence for minimally-invasive cardiac surgery? A critical review of scientific and non-scientific information

Abstract Reducing surgical trauma by minimizing skin incisions has transformed abdominal surgery resulting in significant improvements in outcome. In cardiac surgery, such efforts have also been made, but similar benefits..

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In Vitro Evaluation of Pediatric Hollow‐Fiber Membrane Oxygenators on Hemodynamic Performance and Gaseous Microemboli Handling: An International Multicenter/Multidisciplinary Approach

Abstract The objective of this study was to compare the hemodynamic performances and gaseous microemboli (GME) handling ability of two pediatric oxygenators in a simulated pediatric cardiopulmonary bypass (CPB) model..

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