Perfusfind S.L.
thumbnail
0 comment

Klotho as an Early…

Abstract Acute kidney injury is a common complication following cardiac surgery (CSA-AKI). Serum creatinine levels require a minimum of 24–48 h to indicate renal injury. Nevertheless, early diagnosis remains critical..

Read More
thumbnail
0 comment

Heart transplantation using donation…

Abstract Objectives Heart donation after circulatory death was recently reintroduced in the United States with hopes of increasing donor heart availability. We examined its national use and outcomes. Methods The..

Read More
thumbnail
0 comment

Normoxic Management during Cardiopulmonary…

Abstract Optimal oxygen management during pediatric cardiopulmonary bypass (CPB) is unknown. We previously demonstrated an increase in cortical mitochondrial reactive oxygen species and decreased mitochondrial function after CPB using hyperoxic..

Read More
thumbnail
0 comment

Pediatric Hematology and Oncology…

Abstract Objective:  To describe characteristics associated with survival for pediatric patients with an oncologic diagnosis or hematopoietic cell transplant (HCT) supported with extracorporeal membrane oxygenation (ECMO). Design:  Multicenter, retrospective study...

Read More
thumbnail
0 comment

Advances in remote and…

Abstract Introduction Simulation-based learning has become an essential element in entry-level perfusion education. While the use of simulation has been demonstrated to improve patient outcomes, few institutions possess the budgetary..

Read More
thumbnail
0 comment

Pulsatility of Pulmonary Artery…

Abstract Despite technological advances in left ventricular assist device (LVAD) technology, which have made survival competitive with heart transplantation at 2 years, right ventricular failure (RVF), with an incidence of..

Read More
thumbnail
0 comment

Blood Transfusion During Extracorporeal…

Abstract The threshold for packed red blood cell (pRBC) transfusion has been an important focus in the management of critically ill patients since the publication of randomized control trials (RCTs)..

Read More
thumbnail
0 comment

Mechanical-Enhanced and Durable Zwitterionic…

Abstract Blood-contact medical devices are indispensable for clinical interventions, yet their susceptibility to thrombosis and bacterial infections poses substantial risks to treatment efficacy and patient well-being. This study introduces a..

Read More
thumbnail
0 comment

Immediate Clinical Complications Occurring…

Abstract The clinical tolerance of extracorporeal membrane oxygenation (ECMO) membrane changes in acute respiratory distress syndrome (ARDS) patients under veno-venous ECMO (VV-ECMO) has not been reported. The aim of this..

Read More
thumbnail
0 comment

Actual Cost of Extracorporeal…

Abstract OBJECTIVES:  To determine the actual cost and drivers of the cost of an extracorporeal cardiopulmonary resuscitation (E-CPR) care cycle. PERSPECTIVE:  A time-driven activity-based costing study conducted from a healthcare..

Read More
thumbnail
0 comment

Science of left ventricular…

Abstract The concept of left ventricular unloading has its foundation in heart physiology. In fact, the left ventricular mechanics and energetics represent the cornerstone of this approach. The novel sophisticated..

Read More
thumbnail
0 comment

Optimizing Contrast-Enhanced Thoracoabdominal CT…

Abstract Rationale and Objectives To evaluate the quality and value of contrast-enhanced (CE) chest- and abdominal computed tomography (CT) and CT angiography in neonates, children, and adults undergoing extracorporeal membrane..

Read More
thumbnail
0 comment

The Role of Imaging…

Abstract OBJECTIVE. Extracorporeal membrane oxygenation (ECMO) is increasingly widely used in pediatric respiratory failure. Despite playing a key part in patient management during ECMO, the role of radiology is not widely..

Read More
thumbnail
0 comment

Anticoagulation Management in V-V…

Abstract Background: Extracorporeal membrane oxygenation (ECMO) is a complex procedure affecting both the risk of thrombosis and bleeding. High-quality data to personalize anticoagulation management in ECMO are lacking, resulting in..

Read More
thumbnail
0 comment

International Perfusionist Equivalency Assessment…

PROCESS SUMMARY & APPLICATION FORM Overview  The International Perfusionist Equivalency Assessment (IPEA) provides a pathway for internationally trained Perfusionists to become certified in Canada. This process ensures that candidates meet..

Read More
thumbnail
0 comment

Extubated, Rehabilitation-Focused Extracorporeal Membrane…

Abstract During the coronavirus 2019 (COVID-19) pandemic, children suffered severe lung injury resulting in acute respiratory distress syndrome requiring support with extracorporeal membrane oxygenation (ECMO). In this case series, we..

Read More
thumbnail
0 comment

Hemoadsorption therapy for myoglobin…

Abstract Background Rhabdomyolysis describes a syndrome characterized by muscle necrosis and the subsequent release of creatine kinase and myoglobin into the circulation. Myoglobin elimination with extracorporeal hemoadsorption has been shown..

Read More
thumbnail
0 comment

Novel weaning assessment for…

Abstract Introduction Pump-controlled retrograde trial off (PCRTO) is described as an effective weaning strategy for veno-arterial extracorporeal membrane oxygenation (ECMO) in the guidelines. Contrastingly, there is no established weaning strategy..

Read More
thumbnail
0 comment

Signs of Hemolysis Predict…

Abstract Cell-free hemoglobin (CFH) is used to detect hemolysis and was recently suggested to trigger acute lung injury. However, its role has not been elucidated in severe acute respiratory distress..

Read More
thumbnail
0 comment

COVID-19 Drug Treatments Are…

Abstract Drug treatments for coronavirus disease 2019 (COVID-19) dramatically improve patient outcomes, and although extracorporeal membrane oxygenation (ECMO) has significant use in these patients, it is unknown whether ECMO affects..

Read More
thumbnail
0 comment

Insights into the Molecular…

Abstract The endothelial glycocalyx (EGC) is a layer of proteoglycans (associated with glycosaminoglycans) and glycoproteins, which adsorbs plasma proteins on the luminal surface of endothelial cells. Its main function is..

Read More
thumbnail
0 comment

Multiobjective Optimization of Rotodynamic…

Abstract Comprehensive optimization of rotodynamic blood pumps (RBPs) requires the consideration of three partially conflicting objectives: size, hemocompatibility, and motor efficiency. Optimizing these individual objectives independently, the potential of multiobjective..

Read More
thumbnail
0 comment

Perfusion quality odds (PEQUOD)…

Abstract OBJECTIVES The multifactorial dynamic perfusion index was recently introduced as a predictor of cardiac surgery-associated acute kidney injury. The multifactorial dynamic perfusion index was developed based on retrospective data..

Read More
thumbnail
0 comment

Definition and management of…

Abstract Purpose Veno-venous extracorporeal membrane oxygenation (VV-ECMO) is an integral part of the management algorithm of patients with severe respiratory failure refractory to evidence-based conventional treatments. Right ventricular injury (RVI)..

Read More
thumbnail
0 comment

Haptoglobin Administration for Intravascular…

Abstract Introduction Exogenous haptoglobin administration may enhance plasma-free hemoglobin (pfHb) clearance during hemolysis, and reduce its end-organ damage: we sought to systematically review and summarize available evidence on the use..

Read More
thumbnail
0 comment

Activated clotting time value…

Abstract OBJECTIVES Activated clotting time (ACT) is commonly used to monitor anticoagulation during cardiac surgeries. Final ACT values may be essential to predict postoperative bleeding and transfusions, although ideal values..

Read More
thumbnail
0 comment

Outcomes of an extracorporeal…

Abstract Objective To analyze if the implementation of a multidisciplinary extracorporeal cardiopulmonary resuscitation (ECPR) program in a tertiary hospital in Spain is feasible and could yield survival outcomes similar to..

Read More
thumbnail
0 comment

A pharmacokinetic framework describing…

Abstract Cardiopulmonary bypass (CPB) can alter pharmacokinetic (PK) parameters and the drug may adsorb to the CPB device, altering exposure. Cefazolin is a beta-lactam antibiotic used for antimicrobial prophylaxis during..

Read More