Perfusfind S.L.
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The level of urinary IL-18 in acute kidney injury after cardiopulmonary bypass

ABSTRACT This study investigated the diagnostic value of urinary interleukin-18 (uIL-18) in acute kidney injury (AKI) after cardiopulmonary bypass (CPB) in clinical practice. A total of 103 patients who underwent..

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Prostacyclins in Cardiac Surgery: Coming of Age

Abstract Prostacyclin (prostaglandin I2 [PGI2]) is an eicosanoid lipid mediator produced by the endothelial cells. It plays pivotal roles in vascular homeostasis by virtue of its potent vasodilatory and antithrombotic effects...

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Trends and Patterns of Corticosteroid Use During Coronary Artery Bypass Grafting Surgery in the United States

Abstract Background: Several clinical trials have documented clinical benefits associated with prophylactic corticosteroid administration at the time of coronary artery bypass graft (CABG) surgery, including a reduction in the risk..

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Reference change values of plasma and urine NGAL in cardiac surgery with cardiopulmonary bypass

Abstract Objective As with any biomarker, interpretation of changes of  concentration must consider its variability in a specific clinical setting. The aim of this study was to calculate the reference change..

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Intraoperative oxygen concentration and neurocognition after cardiac surgery: study protocol for a randomized controlled trial

Abstract Background Postoperative cognitive dysfunction (POCD) is a common complication of cardiac surgery. Studies have identified potentially injurious roles for cardiopulmonary bypass (CPB) and subsequent reperfusion injury. Cognitive dysfunction has..

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Incidence and etiological mechanism of stroke in cardiac surgery

Abstract Objective We studied patients who had experienced a stroke in the postoperative period of cardiac surgery, aiming to analyse their progression and determine the factors that may influence prognosis..

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Deep hypothermic circulatory arrest or tepid regional cerebral perfusion: impact on haemodynamics and myocardial integrity in a randomized experimental trial

Abstract OBJECTIVES Organ protective management during aortic arch surgery comprises deep hypothermic (18°C) circulatory arrest (DHCA), or moderate hypothermia (28°C/ ‘tepid’) with regional cerebral perfusion (TRCP). The aim of this..

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Open Cardiac Surgery without Blood and Blood Products Transplantation

ABSTRACT Background: Blood transfusions are the most common type of tissue and organ transplantation. Perioperative and postoperative transfusions may cause morbidity and mortality and transfusion should based on only hematocrit values..

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Postcardiotomy VA-ECMO for refractory cardiogenic shock

Abstract Postcardiotomy cardiogenic shock (PCCS) is a rare but catastrophic syndrome that can occur following separation from cardiopulmonary bypass or at any time during the immediate postoperative course. The management..

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A novel augmented venous-drainage model of cardiopulmonary bypass for deep hypothermic circulatory arrest without blood priming

Abstract Objective: Cardiopulmonary bypass (CPB) and deep hypothermic circulatory arrest (DHCA) are commonly used in cardiac surgery. However, the mortality and morbidity are still high in practice. Developing novel protective..

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An Absorbable Hydrogel Spray Reduces Postoperative Mediastinal Adhesions After Congenital Heart Surgery

Abstract Background Adhesions encountered during reoperative cardiac surgery can prolong operative time and increase operative risk. The purpose of this clinical study was to investigate the antiadhesion property of a..

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Perioperative Management of the Adult Patient on Venovenous Extracorporeal Membrane Oxygenation Requiring Noncardiac Surgery

Abstract The use of venovenous extracorporeal membrane oxygenation is increasing worldwide. These patients often require noncardiac surgery. In the perioperative period, preoperative assessment, patient transport, choice of anesthetic type, drug..

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Understanding the impact of accreditation on quality in healthcare: A grounded theory approach

Abstract Objective To explore how organizations respond to and interact with the accreditation process and the actual and potential mechanisms through which accreditation may influence quality. Design Qualitative grounded theory..

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Mortality and morbidity of patients on the waiting list for coronary artery bypass graft surgery

Abstract OBJECTIVES The public health care system in Brazil has extensive waiting lists of patients requiring complex operations such as coronary artery bypass grafting (CABG). The purpose of this study..

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Percutaneous left atrial unloading to prevent pulmonary oedema and to facilitate ventricular recovery under extracorporeal membrane oxygenation therapy

Abstract OBJECTIVES Left-sided unloading during extracorporeal membrane oxygenation (ECMO) therapy is crucial to prevent pulmonary oedema and facilitate ventricular recovery. We present the case of a 55-year-old man under ECMO..

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Engineered Protein Cages for Selective Heparin Encapsulation

Abstract A heparin-specific binding peptide was conjugated to a cowpea chlorotic mottle virus (CCMV) capsid protein, which was subsequently allowed to encapsulate heparin and form capsid-like protein cages. The encapsulation..

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Health System Needs to Establish Cardiac Surgery Centers

Abstract Cardiovascular diseases are the leading cause of mortality worldwide, responsible for nearly 18 million deaths each year. More than 80% of these take place in low- and middle-income countries..

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Molecular Cardioprotection and the Role of Exosomes: The Future Is Not Far Away

Abstract Heart disease is the leading cause of death in men and women in the United States. During the past several decades, research into the role of specific intracellular mediators,..

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Red Blood Cell Exosome Hemoglobin Content Increases After Cardiopulmonary Bypass and Mediates Acute Kidney Injury in an Animal Model

Abstract Objective Hemolysis, characterized by formation of free hemoglobin (Hb), occurs in patients undergoing cardiopulmonary bypass (CPB). However, there is no study of the dynamic changes in red blood cell..

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Dose Estimation for Bivalirudin during Pediatric Cardiopulmonary Bypass

Abstract Aim A typical adult based bivalirudin regimen during cardiopulmonary bypass uses a loading dose of 1 mg.kg‐1 and a circuit prime (volume L x 13 mg) with a subsequent intravenous..

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Validation of Transcutaneous Carbon Dioxide Monitoring Using an Artificial Lung During Adult Pulsatile Cardiopulmonary Bypass

Abstract Measurements of transcutaneous carbon dioxide (tcCO2) have been used in multiple venues, such as during procedures utilizing jet ventilation, hyperbaric oxygen therapy, as well as both the adult and..

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Cardiopulmonary Bypass-Induced Coagulopathy in Paediatric Patients: The Role of Platelets in Postoperative Bleeding. A Preliminary Study

Abstract Introduction Paediatric patients are particularly prone to cardiopulmonary bypass (CPB)‐induced coagulopathy mainly due to haemodilution, consumption of coagulation factors and hypothermia. The aim of the present study was to..

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Neural Network-Based Modeling of the Number of Microbubbles Generated with Four Circulation Factors in Cardiopulmonary Bypass

Abstract The need for the estimation of the number of microbubbles (MBs) in cardiopulmonary bypass surgery has been recognized among surgeons to avoid postoperative neurological complications. MBs that exceed the..

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Cardiac Surgery Outcomes in an Epicenter of the COVID-19 Pandemic

Abstract As New York State quickly became the epicenter of the COVID-19 pandemic, innovative strategies to provide care for the COVID-19 negative patients with urgent or immediately life threatening cardiovascular..

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Endoprótesis vasculares a medida con impresión 3D

A partir de la utilización de impresión 3D, el paciente recibió una respuesta rápida para tratar su patología y fue intervenido con éxito en un procedimiento rápido, efectivo y preciso...

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Aneurisma aórtico abdominal: Del 3D al stent personalizado

Utilizar un modelo 3D para crear la prótesis endovascular a medida le permitió al equipo quirúrgico reducir el tiempo total de la intervención y además generó un ahorro de insumos...

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Simulación a medida en cirugía pediátrica: Drenaje venoso pulmonar anómalo

La reconstrucción virtual fue de suma utilidad para reconocer fácilmente las estructuras y sus límites debido a los marcadores de color.    

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Simulación en cirugía vascular: Entrenamiento 3D para cateterismo

La simulación es una actividad de relevancia ya que provee una manera de aprender procedimientos dentro de un ambiente controlado, brindando protección y mayor seguridad para los pacientes.    

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Tecnología 3D para tomar decisiones en cardiopatías congénitas complejas

En este reporte se analizarán dos casos de alta complejidad y muy similares entre si de dos pacientes pediátricos con cardiopatías congénitas.    

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A case of cytokine hemofiltration and extracorporeal life support as treatment of coronavirus disease 2019 (COVID-19) respiratory failure

Despite the critical role of cytokines in the modulation of the immune response, cytokine hyperactivity has been implicated in the pathogenesis of severe organ failure secondary to sepsis, cardiac surgery,..

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