Perfusfind S.L.
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Experiences of surgeons and perfusionists using del Nido cardioplegia in paediatric cardiac surgery: A qualitative sub-study of the DESTINY trial

Abstract Introduction del Nido cardioplegia had not been commercially available in the United Kingdom prior to the DESTINY trial, a multi-centre individually randomised controlled trial to evaluate whether del Nido..

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Optimizing cardiac surgery outcomes in morbid obesity: Surgical, anesthetic, perfusion, and critical care considerations, a narrative review

Abstract Introduction: The global prevalence of morbid obesity is increasing, presenting challenges in cardiac surgery. Morbid obesity (body mass index ≥40 kg/m2) is associated with a high burden of cardiometabolic comorbidities..

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The Predictive Value of Combined Lactate and Leukocyte Levels for Postoperative Morbidity after Prolonged Cardiopulmonary Bypass

Abstract Objectives To identify a critical cardiopulmonary bypass (CPB) duration threshold predictive of a complicated postoperative course after elective cardiac surgery in the absence of technical complications and to find..

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Introduction of modified blood priming technique in the neonatal and infant populations undergoing congenital heart surgery

Abstract Background: Allogenic blood product transfusion has well-documented risks and adverse outcomes. To limit perioperative transfusions for neonates and infants undergoing cardiac surgery, our institution launched a blood conservation program..

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In situ exploration of endothelial function in vasoplegic syndrome after cardiac surgery with cardiopulmonary bypass: protocol for a single-centre prospective…

Abstract Introduction Vasoplegic syndrome (VS) is a severe complication after cardiac surgery with cardiopulmonary bypass (CPB), characterised by vasodilation, hypotension and vasopressor dependence. Endothelial dysfunction, dysregulated nitric oxide signalling, inflammation..

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Minimally invasive versus conventional extracorporeal circulation in cardiac surgery: A meta-analysis of 41 randomized controlled trials

Abstract Objective We aimed to compare postoperative clinical outcomes between minimally invasive extracorporeal circulation (MiECC) and conventional extracorporeal circulation (CECC) in patients undergoing cardiac surgery. Methods We performed a meta-analysis..

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Hypotension during cardioplegia: a cardiac depressor reflex?

Abstract Profound, transient hypotension refractory to α1-agonists and increased bypass flow during cardioplegia administration (intermittent vasoplegia) is a well-recognized yet unexplained phenomenon in cardiac surgery. Retrograde cardioplegia has been shown..

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Impact of Antegrade Selective Cerebral Perfusion Flow Ranges on Clinical and Neurological Outcomes in Aortic Arch Surgery

Abstract Objectives To evaluate the association between selective antegrade cerebral perfusion (SACP) flow ranges and early clinical outcomes in a large cohort of patients undergoing aortic arch surgery. Methods We..

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Management of Preoperative Anemia: Review of Best Practices in Cardiac Surgery

Abstract Up to 40% of cardiac surgery patients present with preoperative anemia, which is associated with significant risks and management challenges. This review highlights the increased perioperative risk attributable to..

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Cytokine trajectories after cardiopulmonary bypass in children: a systematic review and quantitative synthesis

Abstract Introduction Cardiopulmonary bypass (CPB) provokes a systemic inflammatory response with important consequences for infants and children undergoing repair of congenital heart disease [, , ]. Inflammation engages overlapping coagulation..

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Intraoperative monitoring of myocardial oxygenation during open-heart surgery: feasibility and initial performance

Abstract Myocardial protection during cardiopulmonary bypass relies on intermittent administrations of cardioplegia without continuous, tissue‑level feedback on myocardial oxygen supply and mitochondrial metabolic status. Extended near‑infrared spectroscopy (eNIRS) can enable..

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The Heart–Microbiome Axis: Emerging Relevance in Pediatric Cardiology

Abstract The gut microbiome has emerged as an important regulator of cardiovascular physiology through interconnected metabolic, immune, inflammatory, and endocrine pathways. Although the gut–heart axis has been extensively investigated in..

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Feasibility Study of Renal Negative Pressure Treatment After Cardiac Surgery With Cardiopulmonary Bypass

Abstract Background We conducted a technical feasibility and safety study of intraureteric renal negative pressure treatment (rNPT) in patients with chronic kidney disease undergoing elective cardiac surgery with cardiopulmonary bypass..

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Association of acute normovolemic hemodilution with hematologic inflammatory indices and early clinical outcomes after coronary artery bypass grafting

Abstract Background and Objectives Acute normovolemic hemodilution (ANH) is an established patient blood management strategy in cardiac surgery, but its effects on postoperative inflammatory biomarkers remain unclear. In this study,..

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Early Lower Pulmonary Arterial Diastolic Pressure Monitored With Pulmonary Arterial Catheters Is Associated With Improved Survival During VA ECMO for…

Abstract Background Venoarterial (VA) extracorporeal membrane oxygenation (ECMO) is used to support refractory cardiogenic shock (CS) but may increase peripheral afterload. Invasive hemodynamic measurement and cardiopulmonary congestion during VA ECMO..

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Tandem ECMO/CRRT medical nutrition therapy clinical practice points: A literature review and Delphi consensus on clinical practice

Abstract Background Patients who undergo tandem extracorporeal membrane oxygenation (ECMO) and continuous renal replacement therapy (CRRT) have a high risk of metabolic disturbances, malnutrition, and fluid imbalances. ECMO/CRRT tandem therapy..

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Feasibility and safety of intravenous tolvaptan administration immediately upon ICU admission after cardiac surgery with cardiopulmonary bypass

Abstract Purpose Tolvaptan sodium phosphate (TSP; Samtas®, Otsuka Pharmaceutical, Tokyo, Japan) is a novel intravenous aquaretic diuretic; however, evidence for its use in patients after cardiac surgery is limited. We..

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The Early Assessment of a Newly Developed Maglev Extracorporeal Mechanical Oxygenation System : 14 Day In Vivo Study Report

Abstract Extracorporeal membrane oxygenation (ECMO) is standard for cardiogenic shock, but outcomes remain limited. The BreathMo adult ECMO system with a maglev pump and a low-pressure drop oxygenator was developed...

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Optimising glycaemic control in cardiac surgery: narrative review and author recommendations

Abstract Objectives Diabetes and peri-operative hyperglycaemia are associated with increased morbidity and mortality following cardiac surgery. Despite this, specific guidance on peri-operative glycaemic management during cardiac surgery is lacking in United..

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A porous antioxidant membrane for ECMO: Remodeling oxidative stress response patterns and enhancing blood oxygenation efficiency

Abstract Oxidative stress injury is a critical complication during long-term extracorporeal membrane oxygenation (ECMO) support and is further aggravated in critically ill patients with diabetic metabolic comorbidities. Nevertheless, conventional ECMO..

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Combining Renal Replacement Therapy With ECMO: A Scoping Review of Circuit Configurations

What the review examined The investigators searched PubMed, the Cochrane Library, Web of Science, Embase, and ClinicalTrials.gov, with a final search on February 9, 2026. The review followed JBI and..

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Dysregulation of Autophagy in Circulating Platelets Is Associated with Platelet Dysfunction During Cardiopulmonary Bypass

Abstract Objectives To investigate whether cardiopulmonary bypass (CPB)-induced platelet dysfunction is associated with dysregulated autophagic flux in patients undergoing cardiac surgery. Design Prospective, single-center observational study. Setting A tertiary university..

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Comparative efficacy of leukocyte removal by blood filters in autologous cell salvage

Abstract Background Autotransfusion devices concentrate white blood cells (WBCs) within the washed product that may lead to undesirable clinical effects when reinfused to the patient. This quality improvement project evaluated..

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The Effects of Hollow Fiber Membrane Configuration on Hemodynamic Characteristics, Oxygen Transfer Performance and Thrombosis Risk in Oxygenators: A Numerical…

Abstract Background The effects of hollow fiber membrane (HFM) configuration on hemodynamic characteristics, oxygen transfer performance, and thrombosis risk in oxygenators are not clear, and the present study was accomplished..

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Pharmacology of vasopressors and inotropes during extracorporeal membrane oxygenation

Abstract Background This review aims to provide a concise summary of hemodynamic considerations and the pharmacology and current evidence of vasoactive support, including inotropes and vasopressors, during extracorporeal membrane oxygenation..

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Recent advances in Del Nido cardioplegia: A comprehensive analysis of randomized clinical trials in adult cardiac surgery

Abstract Background: Del Nido cardioplegia (DNC) has extensively been used for pediatric population undergoing cardiac surgery. However, its use in adult cardiac surgeries have been limited thus, its benefits are..

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1st isoppt congress - Febr 19/20

International Society for Organ Preservation and Perfusion Therapy (ISOPPT) 1st isoppt congress Date: February 19th-20th, 2027 Venue: Turin, Italy CONGRESS PRESIDENT: Renato Romagnoli

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Lunar phases, meteorological conditions, astrological signs, and postoperative outcomes of acute type A aortic dissection: Results of a retrospective cohort…

Abstract Background Acute type A aortic dissection (ATAAD) is a surgical emergency associated with high mortality. While patient-related risk factors are well-established, beliefs persist regarding the influence of lunar phases,..

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Reducing Anticoagulation in ECMO - 27 Oct

27th October 2026, 16:00-17:30 CET Reducing Anticoagulation in ECMO Moderators: Mark Davidson, Nina Buchtele Speakers and Schedule: 16:00 | Introduction            Mark Davidson (United Kingdom), Nina..

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EUROELSO 2027 - 28 April/1 May

Dear colleagues, members and friends, The EuroELSO Team and faculty are delighted to invite you to the EuroELSO Congress in Vienna, taking place from April 28th to May 1st, 2027,..

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