Perfusfind S.L.
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Biomarkers for acute kidney injury: a pragmatic approach

Abstract Traditionally, the diagnosis of kidney disease has relied primarily on serum creatinine (SCr). For acute kidney injury (AKI), changes in urine output (UO) have also been recognized as a..

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Sex differences in venoarterial extracorporeal membrane oxygenation utilisation and clinical outcomes in Australia

Abstract Background Venoarterial extracorporeal membrane oxygenation (VA-ECMO) is increasingly utilised in critically ill patients with severe cardiac failure and cardiac arrest, yet sex-specific differences in presentation, utilisation, and clinical outcomes..

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Applied physiology at the bedside: using invasive blood pressure as a true monitoring tool

Abstract Invasive arterial blood pressure (BP) monitoring is a cornerstone of hemodynamic assessment in critically ill patients. This review explores how the individual components of BP—systolic arterial (SAP), diastolic arterial..

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Child Opportunity, Race, and Language in Congenital Cardiac Surgery Outcomes

Abstract Racial and ethnic disparities and language barriers coexist with inequities in a child’s educational, environmental, and economic opportunity. We evaluated the association between surgical outcomes and a composite child..

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Acute normovolaemic haemodilution after cardiac surgery: a meta-analysis of randomised controlled trials

Abstract Background Acute normovolaemic haemodilution (ANH) is a widely adopted packed red blood cells (pRBC) transfusion sparing strategy after cardiac surgery. While the intraoperative effect is plausible and likely enhanced..

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Beyond Concentration: Importance of Functional and Temporal Assessment of Fibrinogen After Cardiopulmonary Bypass

Abstract Terada et al. presented an important study on the dynamic relationship between plasma fibrinogen concentration and functional clot strength after cardiopulmonary bypass (CPB). Their findings underscore the multifactorial nature of..

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Comparison of 6% hydroxyethyl starch 130/0.4 vs 5% albumin in cardiopulmonary bypass for cardiac surgery

Abstract BACKGROUND The choice of priming and volume replacement fluids during cardiopulmonary bypass (CPB) in cardiac surgery impacts hemodynamic stability, coagulation, renal function, and patient outcomes. Hydroxyethyl starch (HES) 130/0.4..

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Advances in Extracorporeal Life Support: A Pediatric Perspective

Abstract The last 10 years have seen an exponential rise in the use of extracorporeal life support (ECLS), also frequently referred to as ECMO (extracorporeal membrane oxygenation) when a membrane..

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Highlights of the Nineteenth International Conference on Pediatric Mechanical Circulatory Support Systems and Pediatric Cardiopulmonary Perfusion

Abstract The 19th International Conference on Pediatric Mechanical Circulatory Support Systems and Pediatric Cardiopulmonary Perfusion took place on May 16 and 17, 2025, at the InRad Events Center of the..

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Anticoagulation Management of Patients with Antiphospholipid Syndrome Undergoing Cardiopulmonary Bypass in Cardiac Surgery: Challenges and Current Strategies

Abstract The antiphospholipid syndrome (APS) is a complex autoimmune disease that causes a state of hypercoagulability that can result in recurrent venous and arterial thromboses. APS may lead to cardiac..

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Association between autologous blood transfusion and serum creatinine in patients with acute Stanford-A aortic dissection based on a retrospective study

Abstract Background Autologous blood transfusion (ABT), as a blood conservation strategy, is widely used in surgeries for acute Stanford-A aortic dissection(ATAAD). However, investigations into the correlation between ABT and postoperative..

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Risk factors, outcomes, and early prediction of cardiac surgery-associated acute kidney injury: a post hoc subgroup analysis of the Epidemiology…

Abstract Background Cardiac surgery-associated acute kidney injury (CSA-AKI) is a common and important complication. The risk factors for CSA-AKI remain poorly described. We aimed to identify risk factors for CSA-AKI..

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Central Aortic Cannulation as a Primary Strategy in Acute Type A Aortic Dissection Surgery

Abstract Objectives The central cannulation technique was introduced at our institution in 2018 and has evolved into a primary cannulation strategy for acute type A aortic dissection (ATAAD) surgery. This..

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Follow-up of neonates who received ECMO: how are they doing?

Abstract Extracorporeal membrane oxygenation (ECMO) has been used since 1975 to provide temporary cardiorespiratory support in neonates, children, and adults with severe cardiopulmonary conditions unresponsive to conventional therapy. Initially focused..

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Consequences of a toxic workplace environment on psychological safety in anaesthesia and intensive care

Abstract BACKGROUND  Toxic workplace environments in healthcare, characterised by discrimination, bullying, poor communication, and lack of support, have a negative effect on physicians’ well-being and patient safety. Anaesthesiologists and intensivists..

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Predicting intraoperative transfusion volumes of blood products in cardiovascular surgery: a retrospective study

Abstract Background and Objectives Red blood cells are often overprepared for surgery, leading to waste and increased costs, despite the need for cross-matching tests. This study aimed to develop a..

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Restoring the Morphology and Function of Damaged Red Blood Cells

Abstract Red blood cells (RBCs) play a crucial role in delivering oxygen to tissues with their distinctive shape. However, the mechanisms underlying cellular deformation and rupture due to stress, which..

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Extracorporeal Membrane Oxygenation (ECMO) for Acute Respiratory Distress Syndrome (ARDS) During Pregnancy: A Systematic Review

Abstract Acute respiratory distress syndrome (ARDS) in pregnancy is rare but life-threatening. Extracorporeal membrane oxygenation (ECMO) has been used as rescue therapy in refractory cases, though evidence remains limited. This..

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ECMO patient energy requirements: A descriptive, retrospective cohort study

Abstract Background Indirect calorimetry (IC) in patients receiving extracorporeal membrane oxygenation (ECMO) is complicated. This study presents a novel IC method for this population and compares energy expenditure (EE) from..

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Standard coagulation assays during cardiopulmonary bypass predict post-bypass levels in cardiac surgery

Abstract Background Cardiac surgery with cardiopulmonary bypass (CPB) requires precise hemostasis management to limit postoperative bleeding. Fibrinogen, platelet count, and pro-coagulant factors guide transfusion decisions, yet Clauss fibrinogen measurement during..

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Perioperative tight glucose control regimens for preventing surgical site infections following cardiac surgery-a systematic review and metanalysis of randomized controlled…

Abstract Background Perioperative hyperglycemia is common during cardiac surgery and has been linked to an increased risk of surgical site infections (SSIs). However, the benefits of perioperative tight glucose control..

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ECMO decannulation is associated with dynamic changes in coagulation profiles: an exploratory, nested cohort study

Abstract Background ECMO-associated coagulopathy is a common phenomenon in patients undergoing ECMO therapy. However, data on coagulation trajectories in the post ECMO decannulation period are limited. This study aimed to..

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Marginal Band Collapsing: Structural Insights Into Shear-Induced Platelet Activation Relevant to Circulatory Assist Devices

Abstract Shear-induced platelet activation and receptor shedding in mechanical circulatory support (MCS) paradoxically increase risks of thrombosis and bleeding. Although flow cytometry commonly assesses platelet activation and receptor expression, correlations..

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Comparative Analysis of Pressure Drop (Δp): Hemodynamic Performance of Three Commercial Oxygenators During Cardiopulmonary Bypass

Abstract Background The membrane oxygenator is a critical component of extracorporeal circulation (ECC), whose performance directly depends on its structural architecture. Differences in fiber geometry and winding patterns lead to..

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ECOS-TCS - 23/24 June

The next edition of the International ECOS-TCS Congress is planned on June 23-24, 2026 in Paris, at the Institut du Cerveau, at the Pitié Salpêtrière Hospital. Extracorporeal Organ Support (ECOS)..

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Paris pediatric ecmo course - 15/19 June

Paris pediatric ecmo course June 15-19, 2026 Language will be English. Intensive teaching program: 5 days The program will be interactive, with lectures, case studies and a lot of time devoted to..

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Integrating Continuous Renal Replacement Therapy into Ex-situ Normothermic Liver Machine Perfusion

Abstract Ex situ normothermic machine perfusion (NMP) of the liver has emerged as a dynamic preservation strategy, enabling the maintenance of metabolic activity and assessment of grafts prior to transplantation. Prolonged..

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Outcomes of Abdominal Exploration in ECMO-Supported Patients: A Multicenter ICU Cohort Study

Abstract Objectives Exploratory laparotomy, when required as a treatment for abdominal complications of post–extracorporeal membrane oxygenation (ECMO) initiation, carries a high mortality rate that approaches 80% to 100%. However, studies..

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Temporary mechanical support in fulminant myocarditis: prognostic factors and clinical implications from the FULLMOON study

Abstract Background: Temporary mechanical circulatory support (t‑MCS) is increasingly used in fulminant myocarditis (FM), yet long‑term outcomes and risk factors remain poorly defined.   Methods: From the FULLMOON international cohort..

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Association Between Hospital-Level Volume of Extracorporeal Membrane Oxygenation and Complications: A Clustered, Mixed-Effect Analysis of the Extracorporeal Life Support Organization…

Abstract Objective:  Extracorporeal membrane oxygenation (ECMO) has been used to provide pulmonary and circulatory support in patients with ongoing critical illness. Studies investigating whether an association exists between ECMO center-volume..

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