Abstract Introduction: To understand the behavior of platelet volume indices and the von Willebrand factor (VWF), in vitro experiments using whole human blood were performed with extracorporeal circulation (ECC) circuits,..
Lee masAbstract Ex vivo hemocompatibility testing is a vital element of preclinical assessment for blood-contacting medical devices. Current approaches are resource intensive; thus, we investigated the feasibility of accelerating hemocompatibility testing by standardizing..
Lee masAbstract Nonsurgical bleeding occurs in a significant proportion of patients implanted with continuous-flow ventricular assist devices (CF-VADs) and is associated with nonphysiologic flow with diminished pulsatility. An in vitro vascular pulse perfusion model seeded..
Lee masAbstract Objectives The objective was to compare primary between adult ECMO patients and cardiac surgical patients before and . Furthermore, the authors explored whether in vitro treatment of ECMO patient blood samples with (vWF)..
Lee masBackground Recent data suggest that contributes to (LVAD) , but the mechanism is unknown. In a clinical study, we measured plasma free hemoglobin (pfHgb) and the incidence of LVAD thrombosis. In an in..
Lee mas