Etiquetas Archivo: von Willebrand factor

thumbnail
0 comentario

Platelet volume indices and von Willebrand factor levels in blood exposed to polymer- or heparin-coated membrane oxygenators

Abstract Introduction: To understand the behavior of platelet volume indices and the von Willebrand factor (VWF), in vitro experiments using whole human blood were performed with extracorporeal circulation (ECC) circuits,..

Lee mas
thumbnail
0 comentario

Accelerated Hemocompatibility Testing of Rotary Blood Pumps

Abstract Ex vivo hemocompatibility testing is a vital element of preclinical assessment for blood-contacting medical devices. Current approaches are resource intensive; thus, we investigated the feasibility of accelerating hemocompatibility testing by standardizing..

Lee mas
thumbnail
0 comentario

von Willebrand Factor and Angiopoietin-2 are Sensitive Biomarkers of Pulsatility in Continuous-Flow Ventricular Assist Device Patients

Abstract Nonsurgical bleeding occurs in a significant proportion of patients implanted with continuous-flow ventricular assist devices (CF-VADs) and is associated with nonphysiologic flow with diminished pulsatility. An in vitro vascular pulse perfusion model seeded..

Lee mas
thumbnail
0 comentario

In Vitro Treatment of Extracorporeal Membrane Oxygenation Coagulopathy with Recombinant von Willebrand Factor or Lyophilized Platelets

Abstract Objectives The objective was to compare primary  between adult ECMO patients and cardiac surgical patients before  and . Furthermore, the authors explored whether in vitro treatment of ECMO patient blood samples with  (vWF)..

Lee mas
thumbnail
0 comentario

Clinical and In Vitro Evidence That Subclinical Hemolysis Contributes to LVAD Thrombosis

Background Recent data suggest that  contributes to  (LVAD) , but the mechanism is unknown. In a clinical study, we measured plasma free hemoglobin (pfHgb) and the incidence of LVAD thrombosis. In an in..

Lee mas