Tags Archives: Vasoplegic syndrome

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Role of Non-catecholamines Vasopressors in the Management of Vasoplegic Syndrome after Cardiopulmonary Bypass: A Scoping Review

Abstract Vasoplegic syndrome is a life-threatening condition characterized by uncontrolled peripheral vasodilation, leading to profound arterial hypotension. Treatments include catecholamines, vasopressin, methylene blue (MB), hydroxocobalamin, angiotensin II, and ascorbic acid...

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Targeting the contributors to vasorelaxation during vasoplegia from cardiopulmonary bypass

Abstract Vasoplegia, a syndrome of noncardiogenic, non-hypovolaemic vasodilatory hypotension is a common complication of cardiac surgery utilising cardiopulmonary bypass. Vasopressor-sparing strategies have been increasingly used in the management of vasoplegia..

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Vasoplegia Syndrome After Cardiac Surgery: Insights Into Mechanisms and Treatment

Abstract Vasoplegia syndrome is a specific form of vasodilatory shock encountered in patients who undergo cardiac surgery, most commonly with cardiopulmonary bypass, which is characterized by severe hypotension in the..

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Vasoplegic syndrome in cardiac surgery: bridging therapeutic gaps with best practices and future research

Abstract Vasoplegic syndrome (VS) is a common and potentially life-threatening complication of cardiac surgery with cardiopulmonary bypass (CPB). It presents a significant haemodynamic challenge that is often difficult to manage..

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Vasoplegic Syndrome Following Bypass: A Comprehensive Review of Pathophysiology and Proposed Treatments

Abstract Following cardiopulmonary bypass (CPB) surgery, patients may experience vasoplegic or vasogenic shock syndrome. This condition has a variable incidence, reaching up to 44% in high-risk patients, with mortality rates..

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Does methylene blue improve outcomes in patients with post-cardiac surgery vasoplegic syndrome?

Abstract OBJECTIVES A best evidence topic was written according to a structured protocol described in ICVTS. The question addressed was ‘In patients with vasoplegic syndrome following cardiac surgery with cardiopulmonary bypass,..

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Does methylene blue improve outcomes in patients with post-cardiac surgery vasoplegic syndrome?

Abstract OBJECTIVES A best evidence topic was written according to a structured protocol described in ICVTS. The question addressed was ‘In patients with vasoplegic syndrome following cardiac surgery with cardiopulmonary bypass,..

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Vasoplegic syndrome in cardiovascular surgery; evaluating effects of Sevoflurane and Glibenclamide in a porcine model

Abstract Background Vasoplegic syndrome is frequently observed during cardiac surgery and resembles a complication of high mortality and morbidity. There is a clinical need for therapy and prevention of vasoplegic syndrome..

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Effects of methylene blue on microcirculatory alterations following cardiac surgery

Abstract BACKGROUND  Methylene blue is used as rescue therapy to treat catecholamine-refractory vasoplegic syndrome after cardiac surgery. However, its microcirculatory effects remain poorly documented. OBJECTIVE  We aimed to study microcirculatory..

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Vasoplegic Syndrome after Cardiopulmonary Bypass in Cardiovascular Surgery: Pathophysiology and Management in Critical Care

Abstract Vasoplegic syndrome (VS) is a common complication following cardiovascular surgery with cardiopulmonary bypass (CPB), and its incidence varies from 5 to 44%. It is defined as a distributive form..

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Early Use of Methylene Blue in Vasoplegic Syndrome: A 10-Year Propensity Score-Matched Cohort Study

Abstract Background: Vasoplegic syndrome is associated with increased morbidity and mortality in patients undergoing cardiac surgery. This retrospective, single-center study aimed to evaluate the effect of early use of methylene..

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Vasoplegic syndrome after cardiovascular surgery: A review of pathophysiology and outcome-oriented therapeutic management

Abstract Background: Vasoplegic syndrome (VPS) is defined as systemic hypotension due to profound vasodilatation and loss of systemic vascular resistance (SVR), despite normal or increased cardiac index, and characterized by..

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Vasoplegic syndrome following cardiothoracic surgery-review of pathophysiology and update of treatment options.

Abstract Vasoplegic syndrome is a common occurrence following cardiothoracic surgery and is characterized as a high-output shock state with poor systemic vascular resistance. The pathophysiology is complex and includes dysregulation..

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Vasoplegia treatments: the past, the present, and the future

Abstract Vasoplegia is a ubiquitous phenomenon in all advanced shock states, including septic, cardiogenic, hemorrhagic, and anaphylactic shock. Its pathophysiology is complex, involving various mechanisms in vascular smooth muscle cells..

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