Tags Archives: transfusion

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Coronary artery bypass surgery without blood transfusion; is it possible?

Abstract Background:  Coronary artery bypass surgery is the most commonly performed cardiac operation and approximately 40-70% of patients require a blood transfusion despite improvements in cardiac surgical techniques. Some preventive..

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Current Evidence and Future Directions of Tranexamic Acid Use, Efficacy, and Dosing for Major Surgical Procedures

Abstract Tranexamic acid reduces blood loss and transfusion requirements with no significant thrombotic adverse effects. Postoperative seizures have been seen in cardiac surgical patients in association with patient (advanced age,..

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Preventing and managing catastrophic bleeding during extracorporeal circulation

Abstract The use of extracorporeal circulation for cardiac surgery and extracorporeal life support poses tremendous challenges to the hemostatic equilibrium given its diametric tendency to trigger hyper‐ and hypocoagulopathy. The..

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Clinical impact of disinvestment in hydroxyethyl starch for patients undergoing coronary artery bypass surgery: a retrospective observational study

Abstract Purpose To examine the effect of discontinuing hydroxyethyl starch (HES) solutions on length of hospital stay, transfusion, risk of death, acute kidney injury (AKI), and dialysis. Methods We conducted..

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Hematocrit and impact of transfusion in patients receiving extracorporeal life support

Abstract Introduction:  Increasing the hematocrit is considered to increase oxygen delivery to the patient, especially when hypoxic conditions exist and the patient may become more stable. The aim of this..

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Preoperative anemia versus blood transfusion: Which is the culprit for worse outcomes in cardiac surgery?

Abstract Background Reducing blood product utilization after cardiac surgery has become a focus of  as studies have suggested improved outcomes. The relative impact of preoperative anemia versus packed red blood cells..

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A red cell preservation strategy reduces postoperative transfusions in pediatric heart surgery patients

Summary Background Blood transfusion has well‐documented adverse effects. As part of a blood conservation initiative at our center, we began routine use of cell saver for all congenital heart surgery..

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Retrograde autologous priming in surgery of thoracic aortic aneurysm

Abstract OBJECTIVES Surgery of thoracic aortic aneurysm (TAA) is associated with blood loss and coagulopathy and a high need for red blood cell (RBC) volume. Retrograde autologous priming (RAP) decreases..

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Shifts of Transfusion Demand in Cardiac Surgery After Implementation of Rotational Thromboelastometry–Guided Transfusion Protocols: Analysis of the HEROES-CS (HEmostasis Registry…

Abstract Objectives Rotational  (ROTEM)-guided transfusion algorithms in cardiac surgery have been proven to be successful in reducing blood loss in randomized controlled trials. Using an institutional  registry of patients in cardiac surgery..

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Comparison of Two Major Perioperative Bleeding Scores for Cardiac Surgery Trials: Universal Definition of Perioperative Bleeding in Cardiac Surgery and…

Abstract Editor’s Perspective What We Already Know about This Topic Major bleeding can occur during cardiac surgery. Although different scoring systems exist, the assessment of bleeding can be variable, and..

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The effect of protamine dosing variation on bleeding and transfusion after heparinisation for cardiopulmonary bypass

Abstract Introduction: Accurate dosing of protamine reversal following on-pump cardiac surgical procedures is challenging, with both excessive and inadequate administration recognised to increase bleeding risk. We aimed to examine the..

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The use of acute normovolemic hemodilution in paediatric cardiac surgery

Abstract Background Acute normovolemic hemodilution (ANH) is considered safe and effective in decreasing perioperative transfusion in paediatric populations undergoing high blood‐loss surgeries. We determined the association between ANH and the..

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Prediction of Postoperative Blood Loss Using Thromboelastometry in Adult Cardiac Surgery: Cohort Study and Systematic Review

Objective The aim was to evaluate the predictive value of  for  in adult cardiac surgery with . Design Retrospective  and systematic review of the literature. Setting A tertiary university hospital. Participants 202 patients undergoing..

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The association between borderline pre‐operative anaemia in women and outcomes after cardiac surgery: a cohort study

Summary Anaemia is common before cardiac surgery and is associated with increased morbidity and mortality. The World Health Organization (WHO) definition of anaemia is lower for women than for men..

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Transfusion and blood stream infections after coronary surgery

Abstract The aim of this study was to evaluate the impact of blood transfusion on bloodstream infections. This study included 2764 patients who underwent isolated coronary artery bypass grafting. Blood..

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Open Cardiac Surgery without Blood and Blood Products Transplantation

ABSTRACT Background: Blood transfusions are the most common type of tissue and organ transplantation. Perioperative and postoperative transfusions may cause morbidity and mortality and transfusion should based on only hematocrit values..

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A Comparison of Prothrombin Complex Concentrate and Recombinant Activated Factor VII for the Management of Bleeding With Cardiac Surgery

Abstract Bleeding following cardiac surgery that warrants transfusion of blood products is associated with significant complications, including increased mortality at 1 year following surgery. Factor concentrates, such as prothrombin complex..

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Determining Optimal Treatment to Correct Preoperative Anemia and Reduce Perioperative Allogeneic Blood Transfusions in Cardiac Surgery: A Retrospective Cohort Study

Abstract Objective Preoperative anemia management reduces red blood cell (RBC) transfusion and adverse outcomes, but how best to optimize the patient’s hemoglobin (Hgb) before cardiac surgery remains unclear. The authors..

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Managing Massive Transfusion Protocol During Cardiopulmonary Bypass in the Setting of Penetrating Traumatic Injury

Abstract A 34-year-old African American man was brought to the trauma resuscitation area with 2 gunshot wounds to his right anterior chest below his clavicle and his left back. On..

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