Tags Archives: surgical procedures

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Clinical Trials Design, Scientific Rigor, and Higher-Level Evidence in Surgery

Abstract There is a perception held by others in the health sciences that surgeons are not adequately assessing surgical procedures. In an Editorial in the Lancet in 1996, entitled, “Surgical Research or..

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New trend: Surgical correction of Ebstein's anomaly using modified cone repair and a combination of different techniques

Abstract Background Ebstein's anomaly,a rare cardiac disease that accounts for <1% of all congenital heart diseases, is a right ventricular myopathy with varying degrees of delamination in the endocardium under..

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Impact of Methylprednisolone on Postoperative Quality of Recovery and Delirium in the Steroids in Cardiac Surgery Trial: A Randomized, Double-blind,…

Abstract Background Inflammation after cardiopulmonary bypass may contribute to postoperative delirium and cognitive dysfunction. The authors evaluated the effect of high-dose methylprednisolone to suppress inflammation on the incidence of delirium..

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Hyperinsulinemic Normoglycemia Does Not Meaningfully Improve Myocardial Performance during Cardiac Surgery: A Randomized Trial

Abstract Background: Glucose–insulin–potassium (GIK) administration during cardiac surgery inconsistently improves myocardial function, perhaps because hyperglycemia negates the beneficial effects of GIK. The hyperinsulinemic normoglycemic clamp (HNC) technique may better enhance..

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Pharmacokinetics of cefazolin delivery via the cardiopulmonary bypass circuit priming solution in infants and children

Abstract Objectives Our aim was to describe the pharmacokinetics of cefazolin in paediatric patients undergoing cardiac surgery with cardiopulmonary bypass (CPB) who received cefazolin for peri-operative surgical prophylaxis in addition..

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Preventing and managing catastrophic bleeding during extracorporeal circulation

Abstract The use of extracorporeal circulation for cardiac surgery and extracorporeal life support poses tremendous challenges to the hemostatic equilibrium given its diametric tendency to trigger hyper‐ and hypocoagulopathy. The..

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Cognitive Decline after Delirium in Patients Undergoing Cardiac Surgery

Abstract What We Already Know about This Topic Cardiac surgery is associated with cognitive decline and postoperative delirium The relationship between postoperative delirium and cognitive decline after cardiac surgery is..

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Perioperative Management of the Adult Patient on Venovenous Extracorporeal Membrane Oxygenation Requiring Noncardiac Surgery

Abstract The use of venovenous extracorporeal membrane oxygenation is increasing worldwide. These patients often require noncardiac surgery. In the perioperative period, preoperative assessment, patient transport, choice of anesthetic type, drug..

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