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Degradation of the Endothelial Glycocalyx Contributes to Metabolic Acidosis in Children Following Cardiopulmonary Bypass Surgery

Abstract Objectives:  Cardiopulmonary bypass surgery is complicated by metabolic acidosis, microvascular dysfunction, and capillary leak. The glycocalyx—a layer of proteins and sugars lining the vascular endothelium—is degraded during cardiopulmonary bypass...

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