Abstract Historically, the surgical literature was defined based on a predominance of case series, case reports, and anecdotal experiences of surgical investigators. But over the past several decades, the methodologic..
Read MoreAbstract Background: Congenital heart disease (CHD) occurs in approximately 1% of all live births, and 3% to 8% of these have until now been considered familial cases, defined as the..
Read MoreAbstract When designing a clinical study, a fundamental aspect is the sample size. In this article, we describe the rationale for sample size calculations, when it should be calculated and..
Read MoreAbstract When designing a clinical study, a fundamental aspect is the sample size. In this article, we describe the rationale for sample size calculations, when it should be calculated and..
Read MoreAbstract Survival analysis incorporates various statistical methods specific to data on time until an event of interest. While the event is often death, giving rise to the phrase ‘survival analysis’,..
Read More





