Abstract Background Pulsatile perfusion is a developing technique that attempts to mimic the natural pulsatile flow of blood during cardiopulmonary bypass (CBP). Purpose This systematic review and meta-analysis was conducted..
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Abstract Rotary Blood Pump (RBP) is a commonly used ventricular assist device. However, the constant speed operation of the blood pump leads to a reduction of blood flow pulsatility, which..
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Introduction The heart is nature’s pulsatile pump, delivering rhythmic surges of blood critical not only for oxygen transport but also for maintaining vascular health. Cardiopulmonary bypass, a lifesaving intervention, often..
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Abstract Objective Acute kidney injury (AKI) affects approximately 30% of patients undergoing cardiac surgery with conventional non-pulsatile cardiopulmonary bypass (CPB). Pulsatile flow has long been proposed for mitigating this complication...
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Abstract This study conducts an in-vitro experiment using a mock circulation system that mimics human circulation to assess the veno-arterial extracorporeal membrane oxygenation (ECMO) system. This study aims to compare the hemodynamic..
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Abstract BACKGROUND: A preservation system, the Organ Care System (OCS; TransMedics) uses normothermic pulsatile perfusion during organ transport for heart transplantation. This system has demonstrated favorable outcomes in hearts recovered..
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Introduction Cardiopulmonary bypass (CPB) has been the cornerstone of modern cardiac surgery, allowing for safe cardiac arrest while maintaining systemic perfusion. However, the debate between pulsatile and non-pulsatile flow during..
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Abstract Background Hypertension is the leading risk factor for subclinical target-organ damage (TOD) and cardiovascular disease (CVD). Little is known about the relationship between different pressure measures and subclinical TOD,..
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Abstract Veno-arterial extracorporeal membrane oxygenation (V-A ECMO) is increasingly used to treat refractory cardiogenic shock, despite randomized clinical trials reporting no difference in outcomes., Although traditional ECMO pumps maintain a constant flow..
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Abstract Cardiogenic shock is associated with high mortality. Patients often require temporary mechanical circulatory support. We aimed to develop a percutaneously implantable, assist device that unloads the left ventricle (LV)..
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Abstract Background Pulsatile flow protects vital organ function and improves microcirculatory perfusion during extracorporeal membrane oxygenation (ECMO). Studies revealed that pulsatile shear stress plays a vital role in microcirculatory function..
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Abstract Measurements of transcutaneous carbon dioxide (tcCO2) have been used in multiple venues, such as during procedures utilizing jet ventilation, hyperbaric oxygen therapy, as well as both the adult and..
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