Tags Archives: priming

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Priming Techniques in Cardiopulmonary Bypass: An Overview.

Introduction Cardiopulmonary bypass (CPB) is a cornerstone of modern cardiac surgery, facilitating complex intracardiac procedures by temporarily assuming the function of the heart and lungs. One of the most critical..

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Customized Priming Strategies for High-Risk Patients: Pediatric, Geriatric, and Renal Compromise Considerations.

Introduction Cardiopulmonary bypass (CPB) is essential in cardiac surgery, but high-risk patients—such as pediatric, geriatric, and renal-compromised individuals—require specialized priming strategies to optimize outcomes. A one-size-fits-all approach can lead to..

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Optimizing Priming Solutions in Cardiopulmonary Bypass: Balancing Hemodynamics, Organ Protection, and Patient Outcomes

Introduction Cardiopulmonary bypass (CPB) is a life-saving technology that temporarily replaces the heart and lungs during cardiac surgery. The choice of priming solution plays a crucial role in maintaining hemodynamic..

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Is it useful to wash stored red blood cells in cardiopulmonary bypass priming fluid for neonatal cardiac surgery? A single-centre…

Abstract Background and Objectives Neonatal cardiac surgery requires careful consideration of cardiopulmonary bypass (CPB) priming fluid composition due to small blood volume and immature physiology. This study investigated the impact..

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Reducing the prime cardiopulmonary bypass volume during paediatric cardiac surgery

Abstract Introduction Despite technological advances, the use of homologous blood to prime the cardiopulmonary bypass (CPB) circuits of infants under 10 kg remains common. However, such rapid massive transfusion may increase..

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A modified low-priming cardiopulmonary bypass system in patients undergoing cardiac surgery with medium risk of transfusion: A randomized controlled trial

Abstract Objectives The FUWAI-SAVE system is a modified low-priming cardiopulmonary bypass (CPB) system. The study aimed to explore whether the FUWAI-SAVE system can reduce the perioperative blood transfusion and its..

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Characterization of Protein Binding on an Extracorporeal Membrane Oxygenation (ECMO) Circuit Following the Priming Procedure

Abstract Extracorporeal membrane oxygenation (ECMO) circuit priming procedures are crucial for removing air bubbles and the albumin in priming solution is thought to create a protective layer against blood exposure..

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Optimization of cardiopulmonary bypass prime fluid to preserve microcirculatory perfusion during on-pump coronary artery bypass graft surgery: PRIME study protocol…

Abstract Background Acute microcirculatory perfusion disturbances and organ edema are important factors leading to organ dysfunction during cardiac surgery with cardiopulmonary bypass (CPB). Priming of the CPB system with crystalloid..

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Fresh Frozen Plasma Versus Solvent Detergent Plasma for Cardiopulmonary Bypass Priming in Neonates and Infants Undergoing Cardiac Surgery: A Retrospective…

Abstract Objective Compared with fresh frozen plasma (FFP), Omniplasma has been attributed to an increased coagulation potential and an increased fibrinolytic potential. This study aimed to compare Omniplasma and FFP..

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Effects of albumin and crystalloid priming strategies on red blood cell transfusions in on-pump cardiac surgery: a network meta-analysis

Abstract Background In on-pump cardiac surgery, the albumin priming strategy could maintain colloid osmotic pressure better than crystalloid solutions and reduce excessive perioperative fluid balance. However, a high-quality meta-analysis is..

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Safety and Efficacy of Albumin for Pump Priming in Cardiac Surgery: A Meta-Analysis

Abstract Objectives To assess the efficacy and safety of albumin as pump priming fluid in cardiac surgery. Design Meta-analysis of randomized controlled trials. Setting Each study was conducted in a..

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Comparison of six percent hydroxyethyl starch 130/0.4 and ringer’s lactate as priming solutions in patients undergoing isolated open heart valve…

Abstract Objectives Colloids are added to the priming solution of the cardiopulmonary bypass (CPB) pump to maintain colloid osmotic pressure and prevent fluid overload. This study aimed to compare the..

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Management of priming fluids in cardiopulmonary bypass for adult cardiac surgery: network meta-analysis

Abstract Background Cardiopulmonary bypass (CPB) is frequently employed for cardiac surgery, and selecting a suitable priming fluid is a prerequisite for CPB. Currently, the commonly used priming fluids in clinics..

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Plasma-Free Strategy for Cardiac Surgery with Cardiopulmonary Bypass in Infants < 10 kg: A Retrospective, Propensity-Matched Study

Abstract Background: Infants < 10 kg undergoing cardiac surgery with cardiopulmonary bypass (CPB) may receive either fresh frozen plasma (FFP) or other solutions in the CPB priming volume. The existing..

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The impact of using fresh frozen plasma in cardiopulmonary bypass preparation on thromboelastometric parameters and receiving blood products among pediatric…

Abstract Introduction: The aim of this study was to determine the effect of fresh frozen plasma (FFP) for priming of cardiopulmonary bypass (CPB) circuit on rotational thromboelastometry (ROTEM) and transfusion in..

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Utilizing retrograde autologous priming for blood conservation in cardiac surgery

Abstract Background The use of crystalloid priming for extracorporeal circuit in adult cardiac surgery causes inevitable haemodilution. The haemodilution can be reduced by using methods such as retrograde autologous priming..

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Modified cardiopulmonary bypass with low priming volume for blood conservation in cardiac valve replacement surgery

Abstract Background The adverse effects of cardiopulmonary bypass during open cardiac surgery, including hemodilution, seem to be inevitable, especially for patients who generally have a relatively lower BMI with relatively..

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The effect of retrograde autologous priming on intraoperative blood product transfusion in coronary artery bypass grafting

Abstract Introduction: Retrograde autologous priming (RAP) of the cardiopulmonary bypass (CPB) circuit could reduce the degree of haemodilution associated with priming with acellular solutions. However, there is no strong evidence to..

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Virtual reality device training for extracorporeal membrane oxygenation

Abstract Extracorporeal membrane oxygenation (ECMO) is a last resort therapy for patients with terminal respiratory failure. In the current worldwide surge of critically ill patients with novel coronavirus disease (COVID-19),..

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Priming solution for neonatal and pediatric cardiopulmonary bypass

Abstract The Priming volume of the oxygenators has been reduced by 75% during the last two decades and it is now possible to go safely on bypass with a priming..

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Hematic Antegrade Repriming: A Reproducible Method to Decrease the Cardiopulmonary Bypass Insult.

Abstract The current practice of cardiopulmonary bypass (CPB) requires a preoperative priming of the circuit that is frequently performed with crystalloid solutions. Crystalloid priming avoids massive embolism but is unable..

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Priming solutions and volume management on CPB

Joe discusses fluid balance, fluid resuscitation and fluid selection in cardiac surgery and the critically ill.   

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Retrograde Autologous Priming in Cardiac Surgery: Results From a Systematic Review and Meta-analysis

Abstract Background:  Retrograde autologous priming (RAP) before cardiopulmonary bypass (CPB) may minimize allogeneic red cell transfusion. We conducted a systematic review of the literature to examine the impact of RAP..

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Is blood a necessary component of the perfusate during isolated limb perfusion – a randomized controlled trial

Abstract Background: Isolated limb perfusion (ILP) is a treatment option for malignancies localized to an extremity and is performed by surgical isolation of the limb which is connected to an extracorporeal..

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Prospective, Randomized Un-Blinded Three Arm Controlled Study in Coronary Artery Revascularization with Minimal Invasive Extracorporeal Circulation Systems (MiECC): Surrogate Parameter…

Abstract Objectives: Minimal extracorporeal circulation techniques and systems (MiECC) may reduce the negative side effects of conventional extracorporeal circulation (ECC). However, it is still unclear as to what this is caused..

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