Abstract We have read with interest the work by Helms et al., a single-center study with 30 patients (16 on veno-venous and 14 on veno-arterial extracorporeal membrane oxy-genation (ECMO)), with..
Read MoreAbstract Angiogenesis is the formation of new blood vessel from existing vessels and is a critical first step in tissue repair following chronic disturbances in healing and degenerative tissues. Chronic..
Read MoreAbstract Background The aim of this retrospective observational study was to explore the early predictive parameters for maximum amplitude in the kaolin with heparinase (HKH) assay (MAHKH) of TEG6s Platelet Mapping..
Read MoreAbstract Introduction Due to a national policy change in the management of unused platelet units from September 2018, there was a drastic increase in the number of platelet units wasted..
Read MoreAbstract Objective This study aimed to investigate the blood protective effect of autologous platelet-rich plasma in aortic root reconstruction under longtime cardiopulmonary bypass. Method Patients who underwent aortic root reconstruction..
Read MoreAbstract Objective The purpose of this study was to explore the relationship between platelet concentration (PLT) (× 109/L) and clot strength measured by maximum amplitude (TEG-MA) in healthy volunteers without a..
Read MoreAbstract BACKGROUND: Postoperative use of platelet function testing to rule out microvascular bleeding due to platelet dysfunction after cardiac surgery still lacks strong reference data and reliable cutoff values, yielding..
Read MoreAbstract To summarized the technology of autologous platelet-rich plasmapheresis and analyzed the product quality, in order to provide safe and effective product guarantee service for clinical treatment. Technical parameters were..
Read MoreAbstract Objectives To investigate the independent association of with hospital mortality and key relevant clinical outcomes in cardiac surgery. Design A single-center, propensity score-matched, retrospective, cohort study. Setting At an American..
Read MoreAbstract Platelets play a key role in maintaining hemostasis. However, dysregulated platelet activation can lead to pathological thrombosis or bleeding. Once a platelet gets activated, it will either become an..
Read MoreAbstract Background Minimally invasive extracorporeal circulation (MiECC) is employed as a strategy to attenuate the physiologic disturbance caused by cardiopulmonary bypass. The aim of this study was to compare the..
Read MoreAbstract Background Minimally invasive extracorporeal circulation (MiECC) is employed as a strategy to attenuate the physiologic disturbance caused by cardiopulmonary bypass. The aim of this study was to compare the..
Read MoreAbstract Platelets are the smallest of the blood cells and are known to be activated during cardiopulmonary bypass. They play a role in many associated complications. Both quantitative and qualitative..
Read MoreAbstract In vitro circulation (cardiopulmonary bypass, CPB) has been widely used in heart surgery. In the past, it was believed that the reduction of platelet count and impaired platelet function..
Read MoreAbstract Background Recent studies characterizing in vitro hemostatic properties of whole blood (WB) leukoreduced (LR) with a platelet-sparing filter have described subtle, if any, changes to viscoelastic clotting; however, reductions..
Read MoreAbstract Introduction: This study explored the nature of the association between intraoperative usage of red blood cell, fresh frozen plasma, cryoprecipitate or platelet transfusions and acute kidney injury. Methods: A..
Read MoreAbstract BACKGROUND: Declining platelet counts may reveal platelet activation and aggregation in a postoperative prothrombotic state. Therefore, we hypothesized that nadir platelet counts after on-pump coronary artery bypass grafting (CABG)..
Read MoreAbstract Thrombocytopenia and impaired platelet function are known as intrinsic drawbacks of cardiac surgery and extracorporeal life supports (ECLS). A number of different factors influence platelet count and function including..
Read MoreAbstract Objectives The aim of this study is to evaluate the possibility of the autologous platelet-rich plasma (PRP) collection from the cardiopulmonary bypass (CPB) circuit and to evaluate its effect..
Read MoreAbstract Diagnosis of heparin induced thrombocytopenia (HIT) is not always easy, especially when a confirmatory functional test is not available. In most cases the diagnosis relies on the combination of..
Read MoreAbstract Background Bleeding contributes to the high mortality of venovenous membrane oxygenation (vvECMO). The development of acquired von Willebrand syndrome (AVWS) has been identified as relevant pathology during ECMO. This study..
Read MoreAbstract Introduction Paediatric patients are particularly prone to cardiopulmonary bypass (CPB)‐induced coagulopathy mainly due to haemodilution, consumption of coagulation factors and hypothermia. The aim of the present study was to..
Read MoreAbstract Platelet Mapping can measure both the degree of platelet inhibition and fibrinogen activation, was not originally designed to measure fibrinogen concentration. Traditional laboratory fibrinogen concentration testing requires around 60..
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