Abstract Background Children undergoing cardiopulmonary bypass (CPB) surgery are vulnerable to bleeding and often require transfusions. Pathogen-reduced (PR) platelets may reduce microbial contamination but are associated with decreased platelet count..
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Abstract Importance Platelet transfusion is a frequent procedure with benefits and risks. Objective To provide recommendations in adult and pediatric populations in whom platelet transfusions are commonly performed. Evidence Review Grading of Recommendations..
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Abstract Objectives: Previous studies have demonstrated an association between transfusion and increased organ dysfunction. We sought to determine the association between transfusion of blood components (red blood cell [RBC], plasma, platelet,..
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Abstract BACKGROUND: Platelet transfusion is common in cardiac surgery, but some studies have suggested an association with harm. Accordingly, we investigated the association of perioperative platelet transfusion with morbidity and..
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Abstract Objectives The aim of this study was to evaluate the incidence of transfusions, including red blood cells (RBC), platelets, and fresh frozen plasma (FFP) during and after coronary artery..
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Abstract Purpose Thrombocytopenia (platelet count < 150 × 109/L) is common in intensive care unit (ICU) patients and is likely associated with worse outcomes. In this study we present international contemporary data on thrombocytopenia..
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Abstract Background Thrombocytopenia, hemorrhage and platelet transfusion are common in patients supportedwith venoarterial extracorporeal membrane oxygenation (VA ECMO). However, current literature is limited to smallsingle‑center experiences with high degrees of..
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Abstract Objectives To investigate the independent association of with hospital mortality and key relevant clinical outcomes in cardiac surgery. Design A single-center, propensity score-matched, retrospective, cohort study. Setting At an American..
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Abstract Massive diffuse bleeding is still a problem in cardiovascular surgery. The first line treatment is platelet concentrate transfusion, although there is still insufficient information regarding efficacy, quantity, and timing...
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Abstract Objectives: To present the recommendations and consensus statements with supporting literature for plasma and platelet transfusions in critically ill neonates and children undergoing cardiac surgery with cardiopulmonary bypass or..
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Abstract Objectives: To describe blood component usage in transfused children with congenital heart disease undergoing cardiopulmonary bypass surgery across perioperative settings and diagnostic categories. Design: Datasets from U.S. hospitals participating..
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Abstract The transfusion of platelets for both prophylaxis and treatment of bleeding is relevant to all areas of medicine and surgery. Historically, guidance regarding platelet transfusion has been limited by..
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