Tags Archives: pediatric cardiac surgery

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Goal-Directed Perfusion to Reduce…

Abstract Introduction Cardiac surgery-associated acute kidney injury (CS-AKI) occurs in up to 40%~60% of paediatric patients and increases postoperative morbidity and mortality. A goal-directed perfusion (GDP) strategy aimed at maintaining..

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Trends and Updates on…

Abstract Perfusion strategies for  have direct consequences on pediatric cardiac surgery outcomes. However, inconsistent study results and a lack of uniform evidence-based guidelines for pediatric cardiopulmonary bypass management have led to..

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Effects of modified ultrafiltration…

Abstract Background: This meta-analysis was performed to review the effects of the addition of modified ultrafiltration (MUF) and conventional ultrafiltration (CUF) to CUF alone on postoperative hemoglobin, surgical and ultrafiltration..

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Current status of brain…

Abstract The long-term neurodevelopmental outcome has been a great concern for cardiac surgeons although it is still unclear. There are some risks regarding the neurological and neuropsychological deficits before, during..

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Intraoperative change of lactate…

Abstract Background A change of serum lactate concentrations appeared to be useful for predicting outcomes in various acute ill settings. However, there is little information on intraoperative change of lactate..

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Thromboelastography During Rewarming for…

Abstract Background Thromboelastography (TEG) predicts bleeding in pediatric patients undergoing cardiac surgery. We hypothesize that TEG parameters at rewarming correlate with post-protamine values and that rewarming TEG is associated with..

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Minimally Invasive Extracorporeal Technologies…

Abstract Minimally invasive extracorporeal technologies (MiECT) are in great expansion in the literature and have an impact in adult cardiac surgery, however, a future challenge will be to expand MiECT..

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Cefazolin prophylaxis in children…

Abstract OBJECTIVES To determine the recommended concentrations of cefazolin to be used for antibiotic prophylaxis during paediatric cardiac surgery with extracorporeal circulation (ECC). METHODS Twenty paediatric patients undergoing cardiac surgery..

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Safety and utility of…

Abstract Introduction: Modified ultrafiltration (MUF) is employed at the termination of cardiopulmonary bypass (CPB) in pediatric and neonatal patients undergoing congenital heart surgery to reduce the accumulation of total body..

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Residual Lesion Diagnostics in…

Abstract Background: To assess the impact of diagnostic procedures in identifying residual lesions during extracorporeal membrane oxygenation (ECMO) on survival after pediatric cardiac surgery. Methods: Between January 2012 and December..

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Antifibrinolytic Drugs for the…

Abstract BACKGROUND:  Bleeding is one of the commonest complications affecting children undergoing cardiac surgery on cardiopulmonary bypass. Antifibrinolytic drugs are part of a multifaceted approach aimed at reducing bleeding, though..

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Association Between Exogenous Nitric…

Abstract Objective To compare the incidence and severity of acute kidney injury following open heart surgery with cardiopulmonary bypass in children after administration of exogenous nitric oxide. Design Retrospective cohort..

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Postoperative Hematocrit and Adverse…

Abstract BACKGROUND:  We sought to examine potential associations between pediatric postcardiac surgical hematocrit values and postoperative complications or mortality. METHODS:  A retrospective, cross-sectional study from the Society of Thoracic Surgeons..

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Evaluating the Impact of…

Abstract Objectives Cardiopulmonary bypass (CPB) predisposes young children to coagulopathy. The authors evaluated possible effects of CPB priming fluids on perioperative bleeding in pediatric cardiac surgery. Design Meta-analysis and systematic..

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Blood pressure variability during…

Abstract Background Blood pressure variability (BPV), defined as the degree of variation between discrete blood pressure readings, is associated with poor outcomes in acute care settings. Acute kidney injury (AKI)..

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The Myocardial Protective Effects…

Abstract Background We investigated the myocardial protective effect of a moderate-potassium cold blood cardioplegic solution (K+, 10 mmol/L) in pediatric cardiac surgery. Methods Sixty-eight pediatric patients with congenital heart disease..

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Does the Volume and…

Abstract Pediatric patients, especially neonates and infants, undergoing cardiac surgery, are at particularly high risk for developing surgical bleeding. After separation from cardiopulmonary bypass (CPB), excessive bleeding in children frequently..

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Initial results from an…

Abstract Background Over recent years, a number of enhanced recovery programs have appeared in first, adult colorectal surgery, and subsequently many other adult surgical specialties. Increasing interest in this approach..

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Oxidative Stress and Indicators…

Abstract Pediatric cardiac surgery induces an increased oxidative stress (OS) response. Increased OS is associated with poor neurologic outcomes in neonatal populations with similar patterns of brain injury. We investigated..

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Impact of Heparin- or…

Abstract Background: Extracorporeal circuit coating has been shown to improve coagulation derangements during pediatric cardiopulmonary bypass (CPB). This study compared platelet function and hemostasis activation in pediatric cardiac surgery conducted with..

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Oxygen Delivery in Pediatric…

Abstract Objective Acute kidney injury (AKI) following pediatric cardiac surgery with cardiopulmonary bypass is a frequently reported complication. This study aims to determine the critical oxygen delivery (DO2i) threshold associated..

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Recent advancements in pediatric…

Abstract Background Pediatric cardiac surgery is in itself very enigmatic and individualized. Presently, there has been a slew of new developments aimed primarily toward pediatric cardiopulmonary bypass for safer, patient-centered..

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A prospective randomized study…

Abstract Conventional ultrafiltration (UF) fails to reverse satisfactorily hemodilution and the rise in total body water (TBW) seen after cardiopulmonary bypass (CPB). We have modified the technique, timing, and placement..

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A prospective randomized study…

Abstract Background: Modified ultrafiltration has been touted as superior to conventional ultrafiltration for attenuating the consequences of hemodilution after cardiac surgery with cardiopulmonary bypass in children. We conducted a prospective randomized..

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Development and Validation of…

Abstract BACKGROUND:  Heparin resistance (HR) is a common finding in pediatric cardiac surgery and generally refers to decreased sensitivity to heparin. Antithrombin (AT) deficiency is considered the primary mechanism of..

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Association Between Plasma Fibrinogen…

Abstract Background Intraoperative hypofibrinogenemia is a major factor associated with increased postoperative blood loss in adult cardiac surgery. However, previous pediatric studies on this topic did not sufficiently adjust for..

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Low-Dose Vasopressin and Renal…

Abstract Background:  Congenital heart surgeries are associated with post-bypass renal and cardiac dysfunctions. The use of low-dose vasopressin has been found to be beneficial in adult cardiac surgeries. Objective:  To..

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Ultrasonic Prediction of Weaning…

Abstract Background and Aim:  To assess the utility of ultrasonic markers like B-line score (LUS), diaphragm thickness (DT), thickening fraction (DTF), and excursion (DE) as predictors of weaning outcomes in..

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