Tags Archives: oxygenator

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A silicon membrane microfluidic oxygenator for use as an artificial placenta with minimal anticoagulation

Abstract Extreme prematurity carries a high burden of morbidity and mortality. The artificial placenta is an emerging therapy that has the potential to improve outcomes in these patients. However, current..

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A Validated CFD Model for Gas Exchange in Hollow Fiber Membrane Oxygenators: Incorporating the Bohr and Haldane Effects

Abstract Chronic respiratory diseases claim nearly four million lives annually, making them the third leading cause of death worldwide. Extracorporeal membrane oxygenation (ECMO) is often the last line of support..

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Case Report: Oxygenator Burst During Minimally Invasive Coronary Artery Bypass Grafting (CABG) – A Critical Perfusion Incident

Abstract This case report discusses a rare and critical perfusion accident during a minimally invasive coronary artery bypass grafting (CAGB) procedure, where a Eurosets Skipper oxygenator burst 3 minutes after..

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A New Multifunction Oxygenator With a Dual-Chamber Gas Exchanger to Reduce Dependence on Oxygen Supply

Abstract Although extracorporeal membrane oxygenation (ECMO) systems have been used to provide temporary support for patients with severe respiratory or cardiac failure, they are often bedridden, in part because of..

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High pressure excursion in a radial design oxygenator

Abstract Oxygenator high-pressure (HPE) is a phenomenon that can occur during cardiopulmonary bypass (CPB) in which the oxygenator inlet pressure increases rapidly, thereby limiting flow. Most perfusionists globally do not..

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Prediction of Thrombus Formation within an Oxygenator via Bioimpedance Analysis

Abstract Established clinical monitoring techniques lack predictive capabilities, emphasizing the need for refinement in MO monitoring towards an early warning system. In this study, an MO was modified by integrating..

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Comparative analysis of oxygenator dysfunction in polymethylpentene oxygenators: A pilot study

Abstract Introduction Polymethylpentene (PMP) oxygenators serve as the primary oxygenator type utilized for ECMO. With the number of PMP oxygenators available, it has become increasingly important to determine differences among..

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Open-Source Image-Based Tool to Experimentally Evaluate Blood Residence Time in Clinical Devices

Abstract This article introduces an open-source tool to experimentally compare blood residence time in biomedical devices using an image-based method. The experimental setup and the postprocessing workflow are comprehensively elucidated..

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Improving ECMO therapy: Monitoring oxygenator functionality and identifying key indicators, factors, and considerations for changeout

Abstract Introduction: The optimal timing for extracorporeal membrane oxygenation (ECMO) circuit change-out is crucial for the successful management of patients with severe cardiopulmonary failure. This comprehensive review examines the various..

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In vitro evaluation of the performance of an oxygenator depending on the non-standard gas content of the inlet blood with…

Abstract Introduction The performance of an oxygenator, as found in literature, is evaluated according to protocols that define standard values of the gas content in the inlet blood. However, when..

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Refurbishment of Extracorporeal Life Support Oxygenators in the Context of In Vitro Testing

Abstract Refurbishing single use extracorporeal membrane oxygenation (ECMO) oxygenators for in vitro research applications is common. However, the refurbishment protocols that are established in respective laboratories have never been evaluated. In the present study, we aim at proving..

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Evaluation of the effects of three designs of oxygenators with integrated filters on clinical and haematological outcomes at an Australasian…

Abstract Introduction: Cardiopulmonary bypass (CPB) machines have oxygenators with integrated filters and unique biocompatible coatings to combat systemic inflammatory response syndrome (SIRS) and mitigate coagulopathy. Contemporary oxygenators have undergone comparative..

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Clinical evaluation of the novel Capiox NX19 adult oxygenator–a multicenter study

Abstract Introduction The novel Capiox NX19 adult oxygenator is, compared to its predecessors, improved with enhanced air removal technology, a polymer heat exchanger and smaller, innovative hollow fibers resulting in..

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Comparison of bubble removal performances of five membrane oxygenators with and without a pre-filter

Abstract When employing minimal invasive extracorporeal circulation (MiECC), the removal of bubbles in the circuit is important to prevent air embolism. We investigated the bubble removal performance of the FHP..

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Clinical evaluation of two adult oxygenator systems in terms of mortality and major adverse events

Abstract Purpose The primary aim of this study was to examine the effects of two oxygenator systems on major adverse events and mortality. Methods A total of 181 consecutive patients..

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EOS ECMO

EOS ECMO is part of the LivaNova ECMO oxygenators family. Equipped with the well known Polymethylpentene Hollow Fiber, it guarantees optimal performance for Pediatric and Adult patients undergoing long duration..

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Toward Development of a Higher Flow Rate Hemocompatible Biomimetic Microfluidic Blood Oxygenator

Abstract The recent emergence of microfluidic extracorporeal lung support technologies presents an opportunity to achieve high gas transfer efficiency and improved hemocompatibility relative to the current standard of care in..

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Novel application of indocyanine green fluorescence imaging for real-time detection of thrombus in a membrane oxygenator

Abstract Extracorporeal membrane oxygenation (ECMO) plays an important role in the coronavirus disease 2019 (COVID-19) pandemic. Management of thrombi in ECMO is generally an important issue; especially in ECMO for..

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Utility of gas inlet pressure monitoring in extracorporeal membrane oxygenation

Abstract Purpose: Purpose: Condensation that clogs the hollow fibers of the oxygenation and accumulation of plasma leaks reduces oxygenated lung capacity. In this study, artificial We evaluated whether monitoring changes..

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The Effects of Nitric Oxide in Oxygenator Sweep Gas During Extracorporeal Circulation in a Neonatal Ovine Model

Abstract Extracorporeal membrane oxygenation is a life-saving intervention, but bleeding complications are frequent. Given that the combination of platelet loss and dysfunction is a major contributor to this acquired bleeding..

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Basics of extra corporeal membrane oxygenation: a pediatric intensivist’s perspective

Abstract Extra Corporeal membrane oxygenation (ECMO) is one of the most advanced forms of life support therapy in the Intensive Care Unit. It relies on the principle where an external..

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Fraction of expired oxygen: an additional safety approach to monitor oxygen delivery to the heart lung machine oxygenator.

Abstract Background: Monitoring oxygen delivery to the oxygenator of a heart lung machine (HLM) is typically accomplished with an O2 analyzer connected to the gas inflow line. It is assumed when..

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The Use of Extracorporeal Circulation in Suspected Brain Dead Organ Donors with Cardiopulmonary Collapse

Abstract Background: Monitoring oxygen delivery to the oxygenator of a heart lung machine (HLM) is typically accomplished with an O2 analyzer connected to the gas inflow line. It is assumed when..

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Oxygenator Is the Main Responsible for Leukocyte Activation in Experimental Model of Extracorporeal Circulation: A Cautionary Tale

Abstract In order to assess mechanisms underlying inflammatory activation during extracorporeal circulation (ECC), several small animal models of ECC have been proposed recently. The majority of them are based on..

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Effect of Oxygenator Size on Air Removal Characteristics: A Clinical Evaluation

Abstract During cardiopulmonary bypass (CPB), gaseous microemboli (GME) are released into the patients’ arterial bloodstream. Gaseous microemboli may contribute to the adverse outcome after cardiac surgery. Recently, two oxygenator models..

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Clinical evaluation of contemporary oxygenators

Abstract Advances in cardiopulmonary bypass equipment have played a critical role in improving outcomes for cardiac surgery patients. Recent advancements include reduced priming volumes, biocompatible coatings and gaseous microemboli handling,..

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The depth of anaesthesia associated with the administration of isoflurane 2.5% during cardiopulmonary bypass

Abstract Background: Administering isoflurane 2.5% into the oxygenator during cardiopulmonary bypass results in no patient movement. However, doing so may result in an excessive depth of anaesthesia particularly, when hypothermia..

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