Abstract BACKGROUNDS In patients with cardiac surgery under cardiopulmonary bypass (CPB), postoperative inflammation is a driver of adverse outcomes. Endotoxaemia is one of the factors thought to trigger this inflammatory..
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Abstract Objective To compare mortality and organ injury associated with intraoperative hyperoxia and normoxia in cardiac surgery patients. Design Systematic review and meta-analysis of randomized clinical trials (RCTs). Setting Tertiary..
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Abstract Cardiopulmonary bypass (CPB) is essential for the conduct of open-heart procedures. While lifesaving, CPB can be associated with significant end-organ injuries believed to result from inflammatory responses triggered by..
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Abstract Background Cardiac surgery is known to induce acute endothelial dysfunction, which may be central to the pathophysiology of postoperative complications. Preoperative endothelial dysfunction could also be implicated in the..
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