Tags Archives: neonatal cardiac surgery

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Neuromonitoring and neuroprotection during neonatal aortic arch surgery: A United Kingdom and Ireland survey

Abstract Introduction Neonatal aortic arch surgery is associated with neurological morbidity of varying severity which is detected and potentially limited through neuroprotective strategies. We conducted a survey of healthcare professionals..

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Tailored preoperative assessment in neonatal cardiac surgery: a European Congenital Heart Surgeons Association study

Abstract OBJECTIVES Current preoperative counselling in neonatal cardiac surgery is mainly focused on the primary procedure. However, other factors must be considered when evaluating the surgical risk of a neonate...

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Prophylactic corticosteroids in neonatal cardiac surgeries using cardiopulmonary bypass: a systematic review and meta-analysis

Abstract Purpose Neonates undergoing cardiopulmonary bypass (CPB) are at a high risk of a systemic inflammatory response leading to cardiac, respiratory, and renal dysfunction due to their small body size..

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Optimal brain perfusion pressure derived from the continuous monitoring of cerebral autoregulation status during neonatal heart surgery under cardiopulmonary bypass…

Abstract Background Understanding cerebral blood flow regulation and later optimizing brain perfusion is part of neuroprotection during cardiopulmonary bypass (CPB) in neonates. Methods A total of 38 neonates undergoing CPB..

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Outcomes of Neonatal Cardiac Surgery: A European Congenital Heart Surgeons Association Study

Abstract Background We evaluated outcomes of neonatal cardiac surgery at hospitals affiliated with the European Congenital Heart Surgeons Association (ECHSA). Methods All patients ≤30 days of life undergoing a cardiac..

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Urine biomarkers, acute kidney injury, and fluid overload in neonatal cardiac surgery

Abstract Background:Cardiac surgery-associated acute kidney injury (CS-AKI) and fluid overload (FO) are common among neonates who undergo cardiopulmonary bypass, and increase mortality risk. Current diagnostic criteria may delay diagnosis. Thus,..

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Outcomes Following Neonatal Cardiac Surgery in Cape Town, South Africa

Abstract Background Neonatal Cardiac Surgery has developed significantly since its advent, with improved outcomes, survival, and physiological repair. Limited programs offer neonatal cardiac surgery in emerging economies. We report our..

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Is it useful to wash stored red blood cells in cardiopulmonary bypass priming fluid for neonatal cardiac surgery? A single-centre…

Abstract Background and Objectives Neonatal cardiac surgery requires careful consideration of cardiopulmonary bypass (CPB) priming fluid composition due to small blood volume and immature physiology. This study investigated the impact..

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Temperature and Neurologic Outcomes in Neonates Undergoing Cardiac Surgery: A Society of Thoracic Surgeons Study

Abstract Background There is significant variability in postoperative neurological injury rates in patients with , with early injuries impacting long-term neurodevelopmental outcomes; therefore, there is an urgent need for identifying effective..

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Population Pharmacokinetics and Target Attainment of Allopurinol and Oxypurinol Before, During, and After Cardiac Surgery with Cardiopulmonary Bypass in Neonates…

Abstract Background The CRUCIAL trial (NCT04217421) is investigating the effect of postnatal and perioperative administration of allopurinol on postoperative brain injury in neonates with critical congenital heart disease (CCHD) undergoing..

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Cerebral autoregulation monitoring using the cerebral oximetry index after neonatal cardiac surgery: A single-center retrospective cohort study

Abstract Objective To investigate whether  is impaired after neonatal cardiac surgery and whether changes in  metrics are associated with different  or the incidence of postoperative neurologic events. Methods This is a retrospective observational..

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Assessment of fluid balance after neonatal cardiac surgery: a description of intake/output vs. weight-based methods

Abstract Background Fluid overload associates with poor outcomes after neonatal cardiac surgery, but consensus does not exist for the most clinically relevant method of measuring fluid balance (FB). While weight..

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Fluid Accumulation After Neonatal Congenital Cardiac Operation: Clinical Implications and Outcomes

Abstract Background This study was conducted to determine the association between fluid balance metrics and mortality and other postoperative outcomes after neonatal cardiac operation in a contemporary multicenter cohort. Methods..

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Impact of a Multidisciplinary Research Team Approach to Prevent Avoidable Mistakes for Neonatal CPB Population

Abstract Significant progress has been made in neonatal cardiopulmonary bypass (CPB) over the years. At Penn State Health Children’s Hospital, we have established a multidisciplinary research team that brings clinicians,..

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Cerebrum and Cardiac Protection with Allopurinol in Neonates with Critical Congenital Heart Disease Requiring Cardiac Surgery with Cardiopulmonary Bypass (CRUCIAL):…

Abstract Background Neonates with critical congenital heart disease (CCHD) undergoing cardiac surgery with cardiopulmonary bypass (CPB) are at risk of brain injury that may result in adverse neurodevelopment. To date,..

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Use of hemoadsorption therapy in neonatal surgery – A case of extreme tetralogy of Fallot and severe pulmonary stenosis undergoing…

This case reports on a 20-day old newborn (weight 3.1 kg, body surface area 0.20 m2), who was diagnosed with an extreme tetralogy of Fallot presenting in a severe cyanotic..

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Epidemiology of Acute Kidney Injury After Neonatal Cardiac Surgery

Abstract Objectives:  Cardiac surgery–associated acute kidney injury occurs commonly following congenital heart surgery and is associated with adverse outcomes. This study represents the first multicenter study of neonatal cardiac surgery–associated acute..

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