Tags Archives: myocardial protection

Perfusfind S.L.

Abstract Background Cardioplegia is delivered via antegrade, retrograde, or combined perfusion routes. Antegrade cardioplegia follows the physiological path but may be less effective in patients with severe coronary disease. Retrograde..

Perfusfind S.L.

Abstract Objective: Coronary artery bypass grafting using cardiopulmonary bypass and cardioplegic arrest is an effective treatment for coronary artery disease. Research suggests supplementing the cardioplegia solution with propofol may be..

Perfusfind S.L.

Abstract Background A main concern during cardiac surgery is the protection of the heart. Myocardial ischemia tends to increase the generation of reactive oxygen species. Based on its oxidation–reduction potentials,..

Perfusfind S.L.

Introduction Cardiopulmonary bypass (CPB) is essential for modern cardiac surgery, allowing complex repairs and reconstructions by diverting blood away from the heart and lungs. However, during this process, the heart's..

Perfusfind S.L.

Abstract Background Reliable myocardial protection is essential for a good outcome after arterial switch operation. Patients and Methods We evaluated 56 neonates with arterial switch operation in this retrospective study...

Perfusfind S.L.

Abstract Background/Objectives: The optimal choice of cardioplegia solution in minimally invasive cardiac surgeries (MICS) remains debated, as prolonged myocardial protection is essential to avoid interruptions to the surgical flow, which..

Perfusfind S.L.

Abstract Cardiac surgery with cardiopulmonary bypass results in global myocardial ischemia–reperfusion injury, leading to significant postoperative morbidity and mortality. Although cardioplegia is the cornerstone of intraoperative cardioprotection, a number of..

Perfusfind S.L.

Abstract Objective: The term “myocardial protection” covers many mechanisms that protect myocardial tissue during cardiac surgery. This includes forms of cardioplegic protection. Two different forms of myocardial protection have been combined..

Perfusfind S.L.

Abstract Myocardial protection and specifically cardioplegia have been extensively investigated in the beginnings of cardiac surgery. After cardiopulmonary bypass had become routine, more and more cardiac operations were possible, requiring..

Perfusfind S.L.

Abstract Background and objective: In this clinical trial, we evaluated if a short-acting nucleoside, adenosine, as a high-dose bolus injection with blood cardioplegia induces faster arrest and provides better myocardial..

Perfusfind S.L.

Abstract Objectives The safe ischemic time after a single-dose del Nido cardioplegia (DNC) infusion has not yet been established. This study evaluated the progression of myocardial ischemic injury to establish the safe ischemic time after a single-dose DNC..

Perfusfind S.L.

Abstract Objective The study objective was to assess the benefits of del Nido cardioplegia compared with cold blood cardioplegia solution in terms of myocardial protection during adult cardiac surgery. Methods..

Perfusfind S.L.

Abstract Objective To review studies that assessed systemic hypothermia as an organ protection strategy in adults undergoing cardiac surgery with cardiopulmonary bypass. Design A systematic review and meta-analysis. Setting and..

Perfusfind S.L.

Abstract Several pieces of evidence suggest that volatile anesthetics (VAs), which were originally used as sedatives, have myocardial protective effects against cardiac ischemia–reperfusion injury. In Europe and the United States,..

Perfusfind S.L.

Abstract Purpose: Myocardial injury due to on-pump coronary artery bypass grafting (CABG) in patients with low ejection fraction (EF) is associated with poor outcomes. This study determines whether intravenous glutamine could..

Perfusfind S.L.

Abstract Aim Cardioplegia is one of the most studied fields of myocardial protection during cardiac surgery. However, the most effective cardioplegia for protection in adult cardiac surgery remains unknown. Method PubMed and other..

Perfusfind S.L.

Abstract This review presents an integrated approach to the analysis of myocardial ischemia and reperfusion injury and the modulating influence of myocardial conditioning during the evolution of acute myocardial infarction..

Perfusfind S.L.

Abstract Background We investigated the myocardial protective effect of a moderate-potassium cold blood cardioplegic solution (K+, 10 mmol/L) in pediatric cardiac surgery. Methods Sixty-eight pediatric patients with congenital heart disease..

Perfusfind S.L.

Abstract Background: In this prospective randomized controlled trial, we compared the standard del Nido cardioplegia solution (SDN) with the modified del Nido cardioplegia solution (MDN) in which the base solution was..

Perfusfind S.L.

Abstract Objective: Adenosine pretreatment reduces injury caused by ischemia-reperfusion. To investigate the hypothesis that adenosine pretreatment would modulate injury induced by cardiopulmonary bypass (CPB) and myocardial ischemia/reperfusion, we conducted a randomized..

Perfusfind S.L.

Abstract Background Many studies have reported that dexmedetomidine protects organs from ischemia/reperfusion-induced injury. However, the mechanism of this protective effect remains inconclusive. Methods Rats were randomly divided into 6 groups..

Perfusfind S.L.

Abstract Background Objective: The aim of the present study was to compare the operative and early postoperative results of the use of del Nido  solution (dNCS) with traditional blood cardioplegia..

Perfusfind S.L.

Abstract Background: The aim of this study is to compare the efficacy of the microplegia solution and Del Nido cardioplegia solution in coronary artery bypass surgery with clinical, biochemical, and..

Perfusfind S.L.

Dedicated solutions for all of the different myocardial protection methods.A wide collection of crystalloid, cold and warm blood cardioplegia systems available for delivering your myocardial protection.[pdf-embedder url="https://perfusfind.com/wp-content/uploads/2021/09/Myocardial-CPL-solutions_09294-82B_compressed.pdf" title="Myocardial CPL solutions_09294-82B_compressed"]..

Perfusfind S.L.

Abstract Background del Nido cardioplegia has been adopted for use in adult cardiac surgery, despite a lack of robust randomised evidence supporting equivalence or superiority to conventional hyperkalaemic blood cardioplegia...

Perfusfind S.L.

Abstract  with current methods of  is still incomplete , , . Several studies have shown that hyperkalemic solution may lead to cell injury , . Adenosine-lidocaine-magnesium (ALM) is a new normokalemic, “polarizing” method of cardioplegia that..

Perfusfind S.L.

Mark Mettauer, MD lectures and discusses a novel technique for myocardial protection during minimally invasive mitral valve surgery. Discussions follow about the systemic hyperkalemia technique.  

Perfusfind S.L.

Abstract The protective effects of preprocedural esmolol on myocardial injury and hemodynamics have not, to date, been investigated in patients who were scheduled for cardiac surgeries under a cardiopulmonary bypass..

Perfusfind S.L.

Abstract OBJECTIVES This study investigates the effects of high glucose content on patients undergoing cold crystalloid versus cold blood cardioplegia in terms of early clinical results, functional myocardial recovery and..

Perfusfind S.L.

Abstract OBJECTIVES:  Combined coronary artery bypass grafting and valve surgery requires a prolonged period of cardioplegic arrest (CA) predisposing to myocardial injury and postoperative cardiac-specific complications. The aim of this..